The effects of multimodal prehabilitation interventions in men affected by prostate cancer on physical, clinical and patient reported outcome measures: a systematic review.

Paterson, Catherine; Roberts, Cara; Kozlovskaia, Maria; Nahon, Irmina; Schubach, Kathryn; Sara, Sally; Sayner, Alesha M. ; De Abreu Lourenco, Richard; Turner, Murray; Chan, Raymond J.; Lam, Thomas; Woo, Henry; Toohey, Kellie

Abstract

To synthesize existing evidence on the effects of multimodal prehabilitation interventions in men affected by prostate cancer on physical, clinical, and patient-reported outcome measures. A systematic review was conducted according to the PRISMA 2020 Statement Guidelines. Electronic databases (ie, Medline, Embase, CINAHL and Cochrane CENTRAL, and clinicaltrials.gov) were searched using key search terms. Articles were assessed according to prespecified eligibility criteria. Data extraction and quality appraisal was conducted. The findings were integrated in a narrative synthesis. Of the 5863 publications screened, 118 articles were assessed in full text and 17 studies met the prescreening eligibility criteria. There were a range of study designs that included randomized controlled clinical trials (n=11), quasi experimental (n=4), cohort (n=1), and case series (n=1), covering a total of 1739 participants. The prehabilitation interventions included physical activity, peer support, pelvic floor muscle training, diet, nurse-led prehabilitation, psychological, and prehabilitation administration of phosphodiesterase-5 inhibitors. Significant heterogeneity existed in the prehabilitation intervention programs for men affected by prostate cancer in terms of the composition, duration, method of administration, and the outcomes measured to quantify their impact. This systematic review has identified that multimodal prehabilitation interventions are an emerging area for practice and research among men affected by prostate cancer. Importantly, there has been a lack of focus on the inclusion of partners as critical companions during this distressing phase of the cancer care continuum. For the moment, all members of the multidisciplinary team caring for people affected by prostate cancer are encouraged to use the findings in this review to inform holistic models of care.

Citation

PATERSON, C., ROBERTS, C., KOZLOVSKAIA, M., NAHON, I., SCHUBACH, K., SARA, S., SAYNER, A.M., DE ABREU LOURENCO, R., TURNER, M., CHAN, R.J., LAM, T., WOO, H. and TOOHEY, K. 2022. The effects of multimodal prehabilitation interventions in men affected by prostate cancer on physical, clinical and patient reported outcome measures: a systematic review. Seminars in oncology nursing [online], 38(5), article 151333. Available from: https://doi.org/10.1016/j.soncn.2022.151333

• Journal Article Type: Article
• Acceptance Date: Aug 20, 2022
• Online Publication Date: Aug 20, 2022
• Publication Date: Oct 31, 2022
• Deposit Date: Aug 29, 2022
• Publicly Available Date: Aug 21, 2023
• Journal: Seminars in oncology nursing
• Print ISSN: 0749-2081
• Electronic ISSN: 1878-3449
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 38
• Issue: 5
• Article Number: 151333
• DOI: https://doi.org/10.1016/j.soncn.2022.151333
• Keywords: Prehabilitation; Prostate cancer; Systematic review; Multimodal; Physical; Clinical; Patient report outcome measures
• Public URL: https://rgu-repository.worktribe.com/output/1740911
• Additional Information: This article has been published with separate supporting information. This supporting information has been incorporated into a single file on this repository and can be found at the end of the document.