Clinical evaluation of painful diabetes peripheral neuropathy in type 2 diabetes patients: lessons from expatriates in the United Arab Emirates.

Hazari, Animesh; Mishra, Vinaytosh; Agouris, Ioannis

Abstract

The high prevalence of Type 2 Diabetes (T2D) in the United Arab Emirates makes it imperative to screen and manage diabetes peripheral neuropathy (DPN) as a priority. Considering the high number of expats from different ethnicity a more thorough approach is necessary. Unfortunately, there are very few studies addressing this issue. The study uses the chi-square test to investigate the dependence of the progression of DNP on ethnic origin. The study uses Pearson Correlation to find the association between three prevalent scales used for the measurement of painful diabetes peripheral neuropathy. Student t-test was used further to investigate the significance of the association. With a p-value (0.004) and p-value (0.015), the study concludes that DPN risk is dependent on the ethnic origin of the residents. The study further found that there is a significant association between three scales for measuring painful diabetes peripheral neuropathy (pDNP), Douleur Neuropathique en 4 questions (DN4), Neurological Symptoms Score (NSS), and Leeds Assessment of Neuropathic Symptoms and Signs (LANNS). The p-value for all pairwise comparisons for the strength of association between scales was found significant at the level of significance 0.05. The study concludes that the risk of DNP is high in Arab-origin residents in UAE and the reasons behind the finding need to be empirically tested to customize its management. The study further finds a significant association between the score of the three scales used for measuring pDNP.

Citation

HAZARI, A., MISHRA, V. and AGOURIS, I. 2023. Clinical evaluation of painful diabetes peripheral neuropathy in type 2 diabetes patients: lessons from expatriates in the United Arab Emirates. Diabetes and metabolic syndrome: clinical research and reviews [online], 17(9), article 102832. Available from: https://doi.org/10.1016/j.dsx.2023.102832

• Journal Article Type: Article
• Acceptance Date: Jul 19, 2023
• Online Publication Date: Jul 23, 2023
• Publication Date: Sep 30, 2023
• Deposit Date: Aug 3, 2023
• Publicly Available Date: Jul 24, 2024
• Journal: Diabetes and metabolic syndrome: clinical research and reviews
• Print ISSN: 1871-4021
• Electronic ISSN: 1878-0334
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 17
• Issue: 9
• Article Number: 102832
• DOI: https://doi.org/10.1016/j.dsx.2023.102832
• Keywords: T2D; Neuropathy; pDNP; Screening; Screening framework; UAE
• Public URL: https://rgu-repository.worktribe.com/output/2026732