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Associations between IGF1, IGFBP2 and TGFß3 genes polymorphisms and growth performance of broiler chicken lines.

Hosnedlova, Bozena; Vernerova, Katerina; Kizek, Rene; Bozzi, Riccardo; Kadlec, Jaromir; Curn, Vladislav; Kouba, Frantisek; Fernandez, Carlos; Machander, Vlastislav; Horna, Hana

Authors

Bozena Hosnedlova

Katerina Vernerova

Rene Kizek

Riccardo Bozzi

Jaromir Kadlec

Vladislav Curn

Frantisek Kouba

Carlos Fernandez

Vlastislav Machander

Hana Horna



Abstract

The main goal of breeding programs for broiler chickens is to increase growth rate and breast and thigh muscles weight. The candidate gene approach is a powerful technique for genetically improving performance traits in chickens. We studied the associations of the single nucleotide polymorphisms of three genes involved in protein synthesis, glucose metabolism and cell proliferation (IGF1, IGFBP2, TGFβ3) with performance traits in the Hubbard F15 and Cobb E chicken lines. Based on our results, it can be concluded that the TGFβ3 gene could be used as a candidate gene marker for chicken growth traits.

Journal Article Type Article
Publication Date May 31, 2020
Journal Animals
Publisher MDPI
Peer Reviewed Peer Reviewed
Volume 10
Issue 5
Article Number 800
Institution Citation HOSNEDLOVA, B., VERNEROVA, K., KIZEK, R., BOZZI, R., KADLEC, J., CURN, V., KOUBA, F., FERNANDEZ, C., MACHANDER, V. and HORNA, H. 2020. Associations between IGF1, IGFBP2 and TGFß3 genes polymorphisms and growth performance of broiler chicken lines. Animals [online], 10(5), article ID 800. Available from: https://doi.org/10.3390/ani10050800
DOI https://doi.org/10.3390/ani10050800
Keywords Chicken; SNP; IGF1; IGFBP2; TGFß3; Hubbard F15; Cobb E; Growth; Meat

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