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Silver nanomaterials for wound dressing applications.

Krishnan, Priya Dharshini; Banas, Dominik; Durai, Ramya Devi; Kabanov, Daniil; Hosnedlova, Bozena; Kepinska, Marta; Fernandez, Carlos; Ruttkay-Nedecky, Branislav; Nguyen, Hoai Viet; Farid, Awais; Sochor, Jiri; Narayanan, Vedha Hari B.; Kizek, Rene

Authors

Priya Dharshini Krishnan

Dominik Banas

Ramya Devi Durai

Daniil Kabanov

Bozena Hosnedlova

Marta Kepinska

Carlos Fernandez

Branislav Ruttkay-Nedecky

Hoai Viet Nguyen

Awais Farid

Jiri Sochor

Vedha Hari B. Narayanan

Rene Kizek



Abstract

Silver nanoparticles (AgNPs) have recently become very attractive for the scientific community due to their broad spectrum of applications in the biomedical field. The main advantages of AgNPs include a simple method of synthesis, a simple way to change their morphology and high surface area to volume ratio. Much research has been carried out over the years to evaluate their possible effectivity against microbial organisms. The most important factors which influence the effectivity of AgNPs against microorganisms are the method of their preparation and the type of application. When incorporated into fabric wound dressings and other textiles, AgNPs have shown significant antibacterial activity against both Gram-positive and Gram-negative bacteria and inhibited biofilm formation. In this review, the different routes of synthesizing AgNPs with controlled size and geometry including chemical, green, irradiation and thermal synthesis, as well as the different types of application of AgNPs for wound dressings such as membrane immobilization, topical application, preparation of nanofibers and hydrogels, and the mechanism behind their antimicrobial activity, have been discussed elaborately.

Journal Article Type Article
Publication Date Sep 30, 2020
Journal Pharmaceutics
Publisher MDPI
Peer Reviewed Peer Reviewed
Volume 12
Issue 9
Article Number 821
Institution Citation KRISHNAN, P.D., BANAS, D., DURAI, R.D., KABANOV, D., HOSNEDLOVA, B., KEPINSKA, M., FERNANDEZ, C., RUTTKAY-NEDECKY, B., NGUYEN, H.V., FARID, A., SOCHOR, J., NARAYANAN, V.H. and KIZEK, R. 2020. Silver nanomaterials for wound dressing applications. Pharmaceutics [online], 12(9), article ID 821. Available from; https://doi.org/10.3390/pharmaceutics12090821
DOI https://doi.org/10.3390/pharmaceutics12090821
Keywords Nanosilver; Therapeutic activity; Antibacterial effect; Synthesis route

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