All Outputs (24)

Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: a comparison of subjective and novel objective methodology. (2024)
Journal Article
NICKOLAY, T., MCGREGOR, G., POWELL, R., BEGG, B., BIRKETT, S., NICHOLS, S., ENNIS, S., BANERJEE, P., SHAVE, R., METCALFE, J., HOYE, A. and INGLE, L. 2024. Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: a comparison of subjective and novel objective methodology. PLoS one [online], 19(3), article number e0299486. Available from: https://doi.org/10.1371/journal.pone.0299486

Cardiopulmonary exercise testing (CPET) is the 'gold standard' method for evaluating functional capacity, with oxygen pulse (O2Pulse) inflections serving as a potential indicator of myocardial ischaemia. However, the reliability and agreement of iden... Read More about Inter- and intra-observer reliability and agreement of O2Pulse inflection during cardiopulmonary exercise testing: a comparison of subjective and novel objective methodology..

Living with myocardial ischaemia and no obstructive coronary arteries: a qualitative study. (2024)
Journal Article
HUMPHREYS, H., PADDOCK, D., BROWN, S., BERRY, C., COWIE, A., DAWKES, S. and NICHOLS, S. 2024. Living with myocardial ischaemia and no obstructive coronary arteries: a qualitative study. Open heart [online], 11(1), article number e002569. Available from: https://doi.org/10.1136/openhrt-2023-002569

This study aims to explore the lived experience of people with myocardial ischaemia with no obstructive arteries. Qualitative study using semistructured interviews using telephone interviews with 17 participants living in the UK. 17 people (2 males,... Read More about Living with myocardial ischaemia and no obstructive coronary arteries: a qualitative study..

Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation. (2023)
Journal Article
JAMES, E., BUTLER, T., NICHOLS, S., GOODALL, S. and O'DOHERTY, A.F. 2023. Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation. British journal of nutrition [online], First View. Available from: https://doi.org/10.1017/S0007114523002374

Dietary education is a core component of cardiac rehabilitation (CR). It is unknown how or what dietary education is delivered across the United Kingdom (UK). We aimed to characterise practitioners who deliver dietary education in UK CR and determine... Read More about Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation..

Remote ischaemic conditioning for fatigue after stroke (RICFAST): a pilot randomised controlled trial. (2023)
Journal Article
MOYLE, B., KUDIERSKY, N., TOTTON, N., SASSANI, M., NICHOLS, S., JENKINS, T., REDGRAVE, J., BAIG, S., NAIR, K.P.S., MAJID, A. and ALI, A.N. 2023. Remote ischaemic conditioning for fatigue after stroke (RICFAST): a pilot randomised controlled trial. Journal of stroke and cerebrovascular diseases [online], 32(12), article number 107420. Available from: https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107420

Post stroke fatigue (PSF) affects 50 % of stroke survivors and can be disabling. Remote ischaemic conditioning (RIC) can preserve mitochondrial function, improve tissue perfusion and may mitigate PSF. This pilot randomised controlled trial evaluates... Read More about Remote ischaemic conditioning for fatigue after stroke (RICFAST): a pilot randomised controlled trial..

Cost-effectiveness of high-intensity interval training (HIIT) vs moderate intensity steady-state (MISS) training in UK cardiac rehabilitation. (2023)
Journal Article
ALBUSTAMI, M., HARTFIEL, N., CHARLES, J.M., POWELL, R., BEGG, B., BIRKETT, S.T., NICHOLS, S., ENNIS, S., HEE, S.W., BANERJEE, P., INGLE, L., SHAVE, R., MCGREGOR, G. and EDWARDS, R.T. [2023]. Cost-effectiveness of high-intensity interval training (HIIT) vs moderate intensity steady-state (MISS) training in UK cardiac rehabilitation. Archives of physical medicine and rehabilitation [online], Articles In Press. Available from: https://doi.org/10.1016/j.apmr.2023.09.005

The objective of this study was to perform a cost-effectiveness analysis of high-intensity interval training (HIIT) compared with moderate intensity steady-state (MISS) training in people with coronary artery disease (CAD) attending cardiac rehabilit... Read More about Cost-effectiveness of high-intensity interval training (HIIT) vs moderate intensity steady-state (MISS) training in UK cardiac rehabilitation..

A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). (2023)
Journal Article
NGAAGE, D.L., MITCHELL, N., DEAN, A., MITCHELL, A., HINDE, S., AKOWUAH, E., DOHERTY, P., NICHOLS, S., FAIRHURST, C., FLEMMING, K., HEWITT, C., INGLE, L. and WATSON, J. 2023. A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). Pilot and feasibility studies [online], 9, article number 79. Available from: https://doi.org/10.1186/s40814-023-01304-3

The aim of this study was to determine the acceptability and feasibility of delivering early outpatient review following cardiac surgery and early cardiac rehabilitation (CR), compared to standard practice to establish if a future large-scale trial i... Read More about A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER)..

Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process. (2023)
Journal Article
MCHALE, S., COWIE, A., BROWN, S., BUTLER, T., CARVER, K., DALAL, H.M., DAWKES, S., DEIGHAN, C., DOHERTY, P., EVANS, J., HINTON, S., JONES, J., MILLS, J., NICHOLS, S. and TAYLOR, R.S. 2023. Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process. Open heart [online], 10(1), article e002248. Available from: https://doi.org/10.1136/openhrt-2022-002248

The purpose of this British Association for Cardiovascular Prevention and Rehabilitation (BACPR) research priority setting project (PSP) was to identify a top 10 list of priority research questions for cardiovascular prevention and rehabilitation (CV... Read More about Research priorities relating to the delivery of cardiovascular prevention and rehabilitation programmes: results of a modified Delphi process..

Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: further insights from the CARE-CR study. (2023)
Journal Article
JAMES, E., GOODALL, S., NICHOLS, S., WALKER, K., CARROLL, S., O'DOHERTY, A.F. and INGLE, L. 2023. Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: further insights from the CARE-CR study. Frontiers in medicine [online], 10, article number 1094733. Available from: https://doi.org/10.3389/fmed.2023.1094733

Low muscle mass disproportionately affects people with coronary heart disease compared to healthy controls but is under-researched and insufficiently treated. Inflammation, poor nutrition and neural decline might contribute to low muscle mass. This s... Read More about Serum transthyretin and aminotransferases are associated with lean mass in people with coronary heart disease: further insights from the CARE-CR study..

High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. (2023)
Journal Article
MCGREGOR, G., POWELL, R., BEGG, B. et al. 2023. High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial. European journal of preventive cardiology [online], 30(9), pages 745-755. Available from: https://doi.org/10.1093/eurjpc/zwad039

There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). The aim of this study was therefore to assess the cl... Read More about High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial..

The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation. (2022)
Journal Article
JAMES, E., OMAN, P., ALI, M., COURT, P., GOODALL, S., NICHOLS, S.J. and O'DOHERTY, A.F. 2022. The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation. BMC public health [online], 22, article number 1457. Available from: https://doi.org/10.1186/s12889-022-13832-3

Falls prevention exercise programmes are evidence-based and recommended for improving physical function in older adults. However, few service evaluations exist to assess the effectiveness of community-delivered interventions in practice. We conducted... Read More about The effectiveness of the Healthworks Staying Steady community-based falls prevention exercise programme to improve physical function in older adults: a 6-year service evaluation..

Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation. (2021)
Journal Article
FRITH, G., CARVER, K., CURRY, S., DARBY, A., SYDES, A., SYMONDS, S., WILSON, K., MCGREGOR, G., AUTON, K. and NICHOLS, S. 2021. Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation. BMC health services research [online], 21, article number 1363. Available from: https://doi.org/10.1186/s12913-021-07363-7

Restrictions on face-to-face contact, due to COVID-19, led to a rapid adoption of technology to remotely deliver cardiac rehabilitation (CR). Some technologies, including Active+me, were used without knowing their benefits. We assessed changes in pat... Read More about Changes in patient activation following cardiac rehabilitation using the Active+me digital healthcare platform during the COVID-19 pandemic: a cohort evaluation..

Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: a CARE CR study. (2021)
Journal Article
NICHOLS, S., ENGIN, B., CARROLL, S., BUCKLEY, J. and INGLE, L. 2021. Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: a CARE CR study. Annals of physical and rehabilitation medicine [online], 64(6), article number 101462. Available from: https://doi.org/10.1016/j.rehab.2020.101462

Exercise prescription guidelines for individuals undergoing cardiovascular rehabilitation (CR) are often based on heart rate training zones and rating of perceived exertion (RPE). United Kingdom guidelines indicate that patients should exercise at an... Read More about Ratings of perceived exertion at the ventilatory anaerobic threshold in people with coronary heart disease: a CARE CR study..

How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR. (2021)
Journal Article
O'DOHERTY, A.F., HUMPHREYS, H., DAWKES, S., COWIE, A., HINTON, S., BRUBAKER, P.H., BUTLER, T. and NICHOLS, S. 2021. How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR. BMJ open [online], 11(4), article e046051. Available from: https://doi.org/10.1136/bmjopen-2020-046051

Objective: To investigate whether exercise-based cardiac rehabilitation services continued during the COVID-19 pandemic and how technology has been used to deliver home-based cardiac rehabilitation. Design: A mixed methods survey including questions... Read More about How has technology been used to deliver cardiac rehabilitation during the COVID-19 pandemic? An international cross-sectional survey of healthcare professionals conducted by the BACPR..

Characterising the application of the "progressive overload" principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. (2020)
Journal Article
KHUSHHAL, A., NICHOLS, S., CARROLL, S., ABT, G. and INGLE, L. 2020. Characterising the application of the "progressive overload" principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme. PLoS ONE (online), 15(8), article number e0237197. Available from: https://doi.org/10.1371/journal.pone.0237197

Recent concerns have cast doubt over the effectiveness of cardiac rehabilitation (CR) programmes for improving cardiorespiratory fitness (CRF) in patients with a history of cardiac disease in the United Kingdom (UK). Through an observational study, w... Read More about Characterising the application of the "progressive overload" principle of exercise training within cardiac rehabilitation: a United Kingdom-based community programme..

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective. (2020)
Journal Article
PYMER, S., NICHOLS, S., PROSSER, J., BIRKETT, S., CARROLL, S. and INGLE, L. 2020. Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective. European journal of preventive cardiology [online], 27(6), pages 579-589. Available from: https://doi.org/10.1177/2047487319852711

In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve (%HRR)) in cardiac rehabilitation programmes. We aimed to determine the accuracy of this approach by comparing it with an objective, thre... Read More about Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective..

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study. (2020)
Journal Article
NICHOLS, S., TAYLOR, C., GOODMAN, T., PAGE, R., KALLVIKBACKA-BENNETT, A., NATION, F., CLARK, A.L., BIRKETT, S.T., CARROLL, S. and INGLE, L. 2020. Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study. International journal of cardiology [online], 305, pages 25-34. Available from: https://doi.org/10.1016/j.ijcard.2020.01.044

Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (VO2peak). This could reduce the potential benefits of CR and explain why CR no longer improves pa... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study..

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: a United Kingdom perspective. (2019)
Journal Article
KHUSHHAL, A., NICHOLS, S., CARROLL, S., ABT, G. and INGLE, L. 2019. Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: a United Kingdom perspective. PLoS ONE [online], 14(6), article number e0217654. Available from: https://doi.org/10.1371/journal.pone.0217654

In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified. We were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the variability in the effect... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: a United Kingdom perspective..

The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake. (2019)
Journal Article
BIRKETT, S.T., NICHOLS, S., SAWREY, R., GLEADALL-SIDDALL, D., MCGREGOR, G. and INGLE, L. 2019. The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake. Sport sciences for health (online), 15(2), pages 443-451. Available from: https://doi.org/10.1007/s11332-019-00552-2

High-intensity interval training (HIIT) and circuit training (CT) are popular methods of exercise, eliciting improvements in cardiorespiratory fitness (CRF). However, direct comparisons of these two training methods are limited. We investigated the e... Read More about The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake..

Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease: a CARE CR study. (2018)
Journal Article
NICHOLS, S., O'DOHERTY, A.F., TAYLOR, C., CLARK, A.L., CARROLL, S. and INGLE, L. 2019. Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease: a CARE CR study. Clinical physiology and functional imaging [online], 39(1), pages 93-102. Available from: https://doi.org/10.1111/cpf.12539

In patients with chronic heart failure, there is a positive linear relationship between skeletal muscle mass (SMM) and peak oxygen consumption (VO2peak); an independent predictor of all-cause mortality. We investigated the association between SMM and... Read More about Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease: a CARE CR study..

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. (2018)
Journal Article
NICHOLS, S., TAYLOR, C., PAGE, R., KALLVIKBACKA-BENNETT, A., NATION, F., GOODMAN, T., CLARK, A.L., CARROLL, S. and INGLE, L. 2018. Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports medicine - open [online], 4, article number 22. Available from: https://doi.org/10.1186/s40798-018-0138-z

Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabolic risk factor profile may be resp... Read More about Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study..