All Outputs (7)

A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate. (2015)
Thesis
SARTAWI, Z. 2015. A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate. Robert Gordon University, MRes Thesis.

Polyelectrolytes are charge-carrying polymers. When two oppositely-charged polyelectrolytes are combined in a solution favouring charge expression, a polyelectrolyte complex can result. These complexes have been shown to be useful in the field of dru... Read More about A novel polyelectrolyte complex between amphiphilic poly (allyl amine) and sodium alginate..

Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B. (2013)
Thesis
MEDU, E.O. 2013. Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B. Robert Gordon University, PhD thesis.

Bacterial resistance is an increasing challenge across the world, which means that there is an urgent need for the rational development of antibacterial compounds that have either novel or multiple mechanisms of action. This study demonstrated that t... Read More about Examination of the antibacterial activities of some semi-synthetic chalcone-derivatives alone and in combination with polymyxin B..

Antimicrobial wafers as a novel technology for infection control in chronic wounds. (2011)
Thesis
LABOVITIADI, O. 2011. Antimicrobial wafers as a novel technology for infection control in chronic wounds. Robert Gordon University, PhD thesis.

Bacterial contamination and persistent infection is a common cause of impaired wound healing. Generally, non-healing wounds display similar physiological features with regards to mixed bacterial flora, ischemia and production of exudate. The applicat... Read More about Antimicrobial wafers as a novel technology for infection control in chronic wounds..

Formulation studies on cysteamine for the treatment of nephropathic cystinosis. (2011)
Thesis
BUCHAN, B.E. 2011. Formulation studies on cysteamine for the treatment of nephropathic cystinosis. Robert Gordon University, PhD thesis.

Nephropathic cystinosis is a rare autosomal recessive disease characterised by raised lysosomal levels of cystine in the cells of almost all organs. It is treated by regular oral and topical administration of the aminothiol, cysteamine (Cystagon TM),... Read More about Formulation studies on cysteamine for the treatment of nephropathic cystinosis..

Investigation into the antimicrobial activity of cationic antibacterials. (2011)
Thesis
O'DRISCOLL, N.H. 2011. Investigation into the antimicrobial activity of cationic antibacterials. Robert Gordon University, PhD thesis.

The topic addressed by the 2011 WHOs World Health Day was antibacterial resistance. This action served to highlight the serious problem bacterial resistance now presents to healthcare professionals globally. This investigation focussed on the action... Read More about Investigation into the antimicrobial activity of cationic antibacterials..

The molecular mechanisms of diabetes mediated impaired wound healing and the development of therapeutic strategies. (2011)
Thesis
GADAD, P.C. 2011. The molecular mechanisms of diabetes mediated impaired wound healing and the development of therapeutic strategies. Robert Gordon University, PhD thesis.

Increased levels of blood glucose are associated with the vascular complications of diabetes. Microvascular complications lead to delayed wound healing in patients suffering from diabetes. Hypoxia and hyperglycaemia characterise a wound environment o... Read More about The molecular mechanisms of diabetes mediated impaired wound healing and the development of therapeutic strategies..

Development and evaluation of oral solid dosage forms for colonic delivery of drugs for the treatment of cystinosis. (2010)
Thesis
IBIE, C.O. 2010. Development and evaluation of oral solid dosage forms for colonic delivery of drugs for the treatment of cystinosis. Robert Gordon University, MRes thesis.

Modified-release multiparticulate pellets have been produced by the process of extrusion and spheronisation for colon-targeted delivery of cystamine, a cysteamine derivative. Orally-ingested cysteamine formulations, used in the treatment of cystinosi... Read More about Development and evaluation of oral solid dosage forms for colonic delivery of drugs for the treatment of cystinosis..