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Using artificial intelligence methods for systematic review in health sciences: a systematic review.

Blaizot, Aymeric; Veettil, Sajesh K.; Saidoung, Pantakarn; Moreno‐Garcia, Carlos Francisco; Wiratunga, Nirmalie; Aceves‐Martins, Magaly; Lai, Nai Ming; Chaiyakunapruk, Nathorn


Aymeric Blaizot

Sajesh K. Veettil

Pantakarn Saidoung

Magaly Aceves‐Martins

Nai Ming Lai

Nathorn Chaiyakunapruk


The exponential increase in published articles makes a thorough and expedient review of literature increasingly challenging. This review delineated automated tools and platforms that employ artificial intelligence (AI) approaches and evaluated the reported benefits and challenges in using such methods. A search was conducted in 4 databases (Medline, Embase, CDSR, and Epistemonikos) up to April 2021 for systematic reviews and other related reviews implementing AI methods. To be included, the review must use any form of AI method, including machine learning, deep learning, neural network, or any other applications used to enable the full or semi-autonomous performance of one or more stages in the development of evidence synthesis. Twelve reviews were included, using nine different tools to implement 15 different AI methods. Eleven methods were used in the screening stages of the review (73%). The rest were divided: two in data extraction (13%) and two in risk of bias assessment (13%). The ambiguous benefits of the data extractions, combined with the reported advantages from 10 reviews, indicating that AI platforms have taken hold with varying success in evidence synthesis. However, the results are qualified by the reliance on the self-reporting of the review authors. Extensive human validation still appears required at this stage in implementing AI methods, though further evaluation is required to define the overall contribution of such platforms in enhancing efficiency and quality in evidence synthesis.


BLAIZOT, A., VEETTIL, S.K., SAIDOUNG, P., MORENO-GARCIA, C.F., WIRATUNGA, N., ACEVES-MARTINS, M., LAI, N.M. and CHAIYAKUNAPRUK, N. 2022. Using artificial intelligence methods for systematic review in health sciences: a systematic review. Research synthesis methods [online], 13(3), pages 353-362. Available from:

Journal Article Type Article
Acceptance Date Feb 7, 2022
Online Publication Date Feb 28, 2022
Publication Date May 31, 2022
Deposit Date Feb 18, 2022
Publicly Available Date Mar 1, 2023
Journal Research Synthesis Methods
Print ISSN 1759-2879
Electronic ISSN 1759-2887
Publisher Wiley Open Access
Peer Reviewed Peer Reviewed
Volume 13
Issue 3
Pages 353-362
Keywords Systematic reviews; Artificial intelligence; Machine learning; Evidence synthesis
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