Using the theoretical domains framework to explore behavioural determinants for medication taking in patients following percutaneous coronary intervention.

Cunningham, Scott; Jebara, Tesnime; Stewart, Derek; Smith, Jamie; Leslie, Stephen J.; Rushworth, Gordon F.

Abstract

The aim of this study was to investigate relationships between factors influencing medication taking and behavioural determinants in patients who have undergone percutaneous coronary intervention (PCI). A cross-sectional survey was undertaken, using a postal questionnaire distributed to PCI patients. The questionnaire was iteratively developed by the research team, with reference to the Theoretical Domains Framework (TDF) of behavioural determinants, reviewed for face and content validity, and piloted. Data were analysed using descriptive and Principal Component Analysis (PCA). Inferential analysis explored relationships between PCA component scores and factors influencing medicating taking behaviour. The adjusted response rate was 62.4% (325/521). PCA gave 3 components: (C1) Self-perceptions of knowledge and abilities in relation to medication taking; (C2) Aspects relating to activities and support in medication taking; (C3) Emotional aspects in taking medication. Generally, respondents held very positive views. Statistically significant relationships between all three components and self-reported chest pain/discomfort indicated patients with ongoing chest pain/discomfort post-PCI are more likely to have behavioural determinants and beliefs which make medication-taking challenging. Respondents who were on 10 or more medications had lower levels of agreement to the C2 and C3 statements indicating challenges associated with their activities / support and anxieties in medication taking. The study concluded that PCI patients show links between TDF behavioural determinants and factors influencing medication taking for those reporting chest pain or polypharmacy. Further research needs to explore the effective design and implementation of behavioural change interventions to reduce the challenge of medication-taking.

Citation

CUNNINGHAM, S., JEBARA, T., STEWART, D., SMITH, J., LESLIE, S.J. and RUSHWORTH, G.F. 2023. Using the theoretical domains framework to explore behavioural determinants for medication taking in patients following percutaneous coronary intervention. International journal of pharmacy practice [online], 31(2), pages 190-197. Available from: https://doi.org/10.1093/ijpp/riac039

• Journal Article Type: Article
• Acceptance Date: Apr 27, 2022
• Online Publication Date: May 26, 2022
• Publication Date: Apr 30, 2023
• Deposit Date: Apr 8, 2022
• Publicly Available Date: May 27, 2023
• Journal: International journal of pharmacy practice
• Print ISSN: 0961-7671
• Electronic ISSN: 2042-7174
• Publisher: Oxford University Press
• Peer Reviewed: Peer Reviewed
• Volume: 31
• Issue: 2
• Pages: 190-197
• DOI: https://doi.org/10.1093/ijpp/riac039
• Keywords: Medication behaviour; Medicine-taking behaviour; Patient behaviour; Coronary heart disease; Adherence
• Public URL: https://rgu-repository.worktribe.com/output/1635461