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Anti-colon cancer activity of endophytic fungal strains from Terminalia chebula Rezt

Shoeb, Mohammad; Kong Thoo Lin, Paul; Nahar, Nilufar

Authors

Mohammad Shoeb

Nilufar Nahar



Abstract

Endophytic microorganisms are fungi or bacteria that live inside the healthy tissues of the host plants causing no apparent symptoms of diseases. Five endophytic fungal strains labeled as IR-1, IR-2, IR-4, IR-6 and IR-7 (identified as Penicillium thiomii) were isolated from the medicinal plant of Terminalia chebula Retz by culture and sub-culture. The ethyl acetate extract of fungal strains, IR-4, IR-6 and IR-7 inhibited the growth of CaCo-2 colon cancer cell lines in MTT assay with IC 50 values of 55, 44 and 67 μg/mL, respectively.

Citation

SHOEB, M., KONG THOO LIN, P. and NAHAR, N. 2012. Anti-colon cancer activity of endophytic fungal strains from Terminalia chebula rezt. Bangladesh journal of pharmacology [online], 12(1), pages 47-49. Available from: https://doi.org/10.3329/bjp.v7i1.10507

Journal Article Type Article
Acceptance Date May 5, 2012
Online Publication Date May 9, 2012
Publication Date Mar 31, 2012
Deposit Date Aug 19, 2022
Publicly Available Date Mar 28, 2024
Journal Bangladesh Journal of Pharmacology
Print ISSN 1991-007X
Electronic ISSN 1991-0088
Publisher Bangladesh Pharmacological Society
Peer Reviewed Peer Reviewed
Volume 7
Issue 1
Pages 47-49
DOI https://doi.org/10.3329/bjp.v7i1.10507
Keywords Colon cancer; Cytotoxicity; Endophytic fungus
Public URL https://rgu-repository.worktribe.com/output/1739941

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