Anti-colon cancer activity of endophytic fungal strains from Terminalia chebula Rezt

Shoeb, Mohammad; Kong Thoo Lin, Paul; Nahar, Nilufar

Abstract

Endophytic microorganisms are fungi or bacteria that live inside the healthy tissues of the host plants causing no apparent symptoms of diseases. Five endophytic fungal strains labeled as IR-1, IR-2, IR-4, IR-6 and IR-7 (identified as Penicillium thiomii) were isolated from the medicinal plant of Terminalia chebula Retz by culture and sub-culture. The ethyl acetate extract of fungal strains, IR-4, IR-6 and IR-7 inhibited the growth of CaCo-2 colon cancer cell lines in MTT assay with IC 50 values of 55, 44 and 67 μg/mL, respectively.

Citation

SHOEB, M., KONG THOO LIN, P. and NAHAR, N. 2012. Anti-colon cancer activity of endophytic fungal strains from Terminalia chebula rezt. Bangladesh journal of pharmacology [online], 12(1), pages 47-49. Available from: https://doi.org/10.3329/bjp.v7i1.10507

• Journal Article Type: Article
• Acceptance Date: May 5, 2012
• Online Publication Date: May 9, 2012
• Publication Date: Mar 31, 2012
• Deposit Date: Aug 19, 2022
• Publicly Available Date: Aug 19, 2022
• Journal: Bangladesh Journal of Pharmacology
• Print ISSN: 1991-007X
• Electronic ISSN: 1991-0088
• Publisher: Bangladesh Pharmacological Society
• Peer Reviewed: Peer Reviewed
• Volume: 7
• Issue: 1
• Pages: 47-49
• DOI: https://doi.org/10.3329/bjp.v7i1.10507
• Keywords: Colon cancer; Cytotoxicity; Endophytic fungus
• Public URL: https://rgu-repository.worktribe.com/output/1739941