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Psychotherapeutic interventions for burns patients and the potential use with Stevens-Johnson syndrome and toxic epidermal necrolysis patients: a systematic integrative review. [Dataset]


Pauline O�Reilly
Data Collector

Pauline Meskell
Data Collector

Barbara Whelan
Data Collector

Bart Ramsay
Data Collector

Alice Coffey
Data Collector

Donal G. Fortune
Data Collector

Saskia Ingen-Housz-Oro
Data Collector

Christopher B. Bunker
Data Collector

Donna M. Wilson
Data Collector

Isabelle Delaunois
Data Collector

Liz Dore
Data Collector

Siobhan Howard
Data Collector

Sheila Ryan
Data Collector


The aim of this systematic integrative review was to synthesize the evidence relating to psychotherapeutic interventions used with adult burns patients and patients with SJS/TEN. The systematic review was guided by Whittemore and Knafl's integrative review process and the PRISMA guidelines. Nine databases were searched for English and French language papers published January 2008 to January 2021. The protocol for the review was registered with PROSPERO. Following a screening process, 17 studies were included in the review. Two themes were identified using content analysis, (i) Empirically supported psychotherapeutic treatments, (ii) Alternative psychotherapeutic treatments. This review revealed no evidence on specific psychotherapeutic interventions for patients with SJS/TEN. Some of the interventions used with burns patients, viz. relaxation therapy, hypnosis and cognitive behavioral therapy showed some significant benefits. However, the evidence for burns patients is mainly focused on pain and pain anxiety as outcomes.


O'REILLY, P., MESKELL, P., WHELAN, B., KENNEDY, C., RAMSAY, B., COFFEY, A., FORTUNE, D.G., WALSH, S., INGEN-HOUSZ-ORO, S., BUNKER, C.B., WILSON, D.M., DELAUNOIS, I., DORE, L., HOWARD, S. and RYAN, S. 2022. Psychotherapeutic interventions for burns patients and the potential use with Stevens-Johnson syndrome and toxic epidermal necrolysis patients: a systematic integrative review. [Dataset] PLoS ONE [online], 17(6), article e0270424. Available from:

Acceptance Date Jun 9, 2022
Online Publication Date Jun 27, 2022
Publication Date Jun 30, 2022
Deposit Date Aug 23, 2022
Publicly Available Date Aug 23, 2022
Publisher Public Library of Science
Keywords Stevens-Johnson syndrome (SJS); Toxic epidermal necrolysis (TEN); Psychological effects; Burns patients; Stress reduction techniques
Public URL
Related Public URLs
Type of Data DOCX, XLSX files and accompanying text file.
Collection Date Jan 31, 2022
Collection Method The aim of the integrative review was to explore and synthesize the evidence relating to psychotherapeutic interventions used with both adult patients with burns and those with SJS/TEN, during the acute stage of the illness. Examples of interventions that were considered for the review included cognitive behavioural therapy, hypnosis, meditation, psychotherapy, and patient centered care. The review did not focus on interventions which involved body massage or the use of oils and aromatherapy as the use of these may be contraindicated with SJS/TEN patients. This review was guided by the integrative review process developed by Whittemore and Knafl [30] and the PRISMA guidelines [31]. (S1 Checklist). This process allows for the inclusion of disparate methodology studies. It is envisaged these findings elicited from the review may in part inform clinical practice. The PICO framework was used to develop and refine the review question. Two populations were included: firstly, adults over 18 years of age presenting with burns (Population. 1), and secondly adults with SJS/TEN (Population. 2). The search terms included synonyms and Medical Sub-Headings (MeSH) describing burns, SJS, TEN and psychotherapeutic interventions. Psychotherapeutic interventions used to manage symptoms of PTS, anxiety, depression, self-esteem, body image, quality of life or pain, within an acute care setting, were the focus (Table 1). The review question was 'What is the evidence on the psychotherapeutic interventions which have been used with either adult burns patients or patients with SJS/TEN, during the acute stage of the illness, to reduce symptoms aligned to PTS and improve quality of life?'. Both quantitative and qualitative studies were included in the review so as to capture the objective and subjective nature of the review question. The protocol for the review was published with the International Prospective Register of Systematic Reviews (CRD42020159134) [32]. A systematic search following PRISMA guidelines [31] was conducted for both populations. Two members of the review team were information specialists and they led the search process. The search included both French and English language papers. French papers were included as there is a national reference center for Toxic Bullous Dermatoses in France. To test for accuracy and sensitivity of the search terms a preliminary search was conducted on MEDLINE (S1 Table). Nine electronic international databases for publications were searched including CINAHL Complete, Medline (Ovid), Embase, Scopus, Web of Science, Cochrane Library, Medline (EBSCO) PsychINFO and Medline (Pubmed). In addition, grey literature was searched using Cogprints, Grey literature reports, LENUS, Mednar, Olaster, OpenGrey, PROSPERO, Science. Gov, WHO Global Index Medicus, HAL-OAR for French research community and DUMAS. The search timeline was January 2008 to January 2021. Records were exported to EndNote and all duplicates and studies outside of the date range were removed. The search yields and exclusions are outlined, for both populations in Figs 1 and 2.