Differential regulation of CYP4Z1 mRNA in human breast cancer cell lines.

Warasiha, Benjamart; Knott, Rachel; McFadyen, Morag

Abstract

CYP4Z1 is a novel cytochrome P450 enzyme that is preferentially expressed in normal breast and neoplastic breast tissue. This poster reported on the results of a study in which an in vitro cell model was used to define the mechanisms regulating CYP4Z1 mRNA expression, by exposing oestrogen receptor positive cell lines to agonists of three independent nuclear receptor pathways: the progesterone receptor (PGR); peroxisome proliferator activated receptor (PPARα); and the glucocorticoid receptor (GCR).

Citation

WARASIHA, B., KNOTT, R. and MCFADYEN, M. 2008. Differential regulation of CYP4Z1 mRNA in human breast cancer cell lines. Presented at the 2008 National Cancer Research Institute cancer conference (NCRI 2008), 5-8 October 2008, Birmingham, UK.

• Presentation Conference Type: Poster
• Conference Name: 2008 National Cancer Research Institute cancer conference (NCRI 2008)
• Start Date: Oct 5, 2008
• End Date: Oct 8, 2008
• Deposit Date: Mar 17, 2023
• Publicly Available Date: May 1, 2023
• Peer Reviewed: Peer Reviewed
• Keywords: Cytochrome P450 enzymes; Breast cancer; mRNA expression
• Public URL: https://rgu-repository.worktribe.com/output/1905613
• Additional Information: The extended abstract for this poster is also held on the NCRI website: https://abstracts.ncri.org.uk/abstract/differential-regulation-of-cyp4z1-mrna-in-human-breast-cancer-cell-lines-2/