The date rape drug, Flunitrazepam: electroanalytical sensing using electrogenerated chemiluminescence.

Lledo-Fernandez, Carlos; Pollard, Pat; Romerosa, Antonio

Abstract

The electro-analytical sensing of Flunitrazepam is reported for the first time utilising [Ru(bpy)3]2+ as a Electrochemiluminescent reagent probe without any sample pre-treatment. The methodology is shown to be useful for quantifying low ng/mL Flunitrazepam in buffer. We have successfully demonstrated the detection of Flunitrazepam over a range of Flunitrazepam concentrations 2000 ng/mL to 50 ng/mL into a pH 4 buffer. A linear response is observed (ECL emission/mV = 0.0094x+6.3204, R2 = 0.9937 and N = 5) with a detection limit of 39 ng/mL (based on 3-sigma).

Citation

LLEDO-FERNANDEZ, C., POLLARD, P. and ROMEROSA, A. 2014. The date rape drug, Flunitrazepam: electroanalytical sensing using electrogenerated chemiluminescence. International journal of electrochemical science [online], 9(1), pages 227-237. Available from: https://doi.org/10.1016/s1452-3981(23)07711-8

• Journal Article Type: Article
• Acceptance Date: Oct 23, 2013
• Online Publication Date: Nov 15, 2013
• Publication Date: Jan 31, 2014
• Deposit Date: Jun 30, 2023
• Publicly Available Date: Jun 30, 2023
• Journal: International Journal of Electrochemical Science
• Print ISSN: 1452-3981
• Electronic ISSN: 1452-3981
• Publisher: Electrochemical Science Group
• Peer Reviewed: Peer Reviewed
• Volume: 9
• Issue: 1
• Pages: 227-237
• DOI: https://doi.org/10.1016/s1452-3981%2823%2907711-8
• Keywords: Flunitrazepam; Electrochemiluminescence and electroanalytical sensing.
• Public URL: https://rgu-repository.worktribe.com/output/1998104
• Publisher URL: http://www.electrochemsci.org/papers/vol9/90100227.pdf