Investigations on sensitivity enhancement of SPR biosensor using tunable wavelength and graphene layers.

Bhavsar, K.; Prabhu, R.

Abstract

Surface plasmon resonance (SPR) is a well-known, rapid and sensitive technique used for probing the biomolecular interactions in real time. Several new approaches have been suggested to improve the sensitivity of SPR sensors over the last two decades. Recently, there have been few reports on using graphene on a metal film based SPR sensor in order to improve the sensitivity. The role of incident light wavelength and graphene layers in sensitivity enhancement is unclear. This paper reports computational investigations on sensitivity enhancement of SPR biosensor using tunable wavelength and graphene layers. The reflectivity of p-polarized incident light has been calculated using the N-layer model for the most common Kretschmann configuration. Sensitivity enhancements over a conventional angular interrogated SPR sensor have been calculated within the wavelength range 600 -1600 nm and up to ten graphene layers. Results indicate that the sensitivity can be enhanced by the increasing the graphene layers on conventional gold coating based SPR biosensor. Sensitivity enhancement is highly dominated by the wavelength of interrogation used in this design. By tuning the wavelength and graphene layers sensitivity of the graphene-based SPR biosensor can be increased.

Citation

BHAVSAR, K. and PRABHU, R. 2019. Investigations on sensitivity enhancement of SPR biosensor using tunable wavelength and graphene layers. IOP conference series: materials science and engineering [online], 499: proceedings of the 4th International conference on structural nano composites (NANOSTRUC 2018), 23-24 May 2018, Berlin, Germany, article number 012008. Available from: https://doi.org/10.1088/1757-899x/499/1/012008

• Journal Article Type: Conference Paper
• Conference Name: 4th International conference on structural nanocomposites (NANOSTRUC 2018)
• Conference Location: Berlin, Germany
• Acceptance Date: Feb 6, 2018
• Online Publication Date: Apr 3, 2019
• Publication Date: Apr 3, 2019
• Deposit Date: May 9, 2019
• Publicly Available Date: May 10, 2019
• Journal: IOP Conference Series: Materials Science and Engineering
• Print ISSN: 1757-8981
• Electronic ISSN: 1757-899X
• Publisher: IOP Publishing
• Peer Reviewed: Peer Reviewed
• Volume: 499
• Article Number: 012008
• DOI: https://doi.org/10.1088/1757-899X/499/1/012008
• Keywords: Surface plasmon resonance; Biomolecular interactions; Real time; Wavelength; Graphene layers
• Public URL: https://rgu-repository.worktribe.com/output/242067