Pharmaceutical electrochemistry: the electrochemical detection of aspirin utilising screen printed graphene electrodes as sensors platforms.
Kruanetr, Senee; Prabhu, Radhakrishna; Pollard, Pat; Fernandez, Carlos
Professor Radhakrishna Prabhu email@example.com
Dr Carlos Fernandez firstname.lastname@example.org
A sensitive electrochemical sensor was designed for acetyl salicylic acid detection using graphene modified Screen Printed Electrodes. The electrochemical response of the sensor with graphene was improved compared to Screen Printed Electrodes without graphene and displayed an excellent analytical performance for the detection of acetyl salicylic acid. The high acetyl salicylic acid loading capacity on the electrode surface and the outstanding electric conductivity of graphene were also discussed in this manuscript. When a range of different concentrations of acetyl salicylic acid from 0.1 to 100 ?M into a pH 4 buffer solution (N defined as the sample size N = 9) were plotted against the oxidation peak a linear response was observed. The detection limit was found to be 0.09 ?M based on (3-?/slope). Screen Printed Graphene electrodes sensors methodology is shown to be useful for quantifying low levels of acetyl salicylic acid in a buffer solution as well as in biological matrixes such as human oral fluid. A linear response was obtained over a range of concentrations from 10 to 150 ?M into a human oral fluid solution (N = 10) giving a detection limit of 8.7 ?M.
KRUANETR, S., PRABHU, R., POLLARD, P. and FERNANDEZ, C. 2015. Pharmaceutical electrochemistry: the electrochemical detection of aspirin utilising screen printed graphene electrodes as sensors platforms. Surface engineering and applied electrochemistry [online], 51(3), pages 283-289. Available from: https://doi.org/10.3103/S1068375515030114
|Journal Article Type||Article|
|Acceptance Date||Sep 22, 2014|
|Online Publication Date||Jul 15, 2015|
|Publication Date||May 31, 2015|
|Deposit Date||Sep 16, 2016|
|Publicly Available Date||Sep 16, 2016|
|Journal||Elektronnaya Obrabotka Materialov / Surface Engineering and Applied Electrochemistry|
|Peer Reviewed||Peer Reviewed|
|Keywords||Acetyl salicylic acid; Electrochemical; Sensor; Modified screen printed electrode|
KRUANETR 2015 Pharmaceutical electrochemistry
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