Theoretical treatment of diffusion and kinetics of osmium redox polymer mediated glucose oxidase enzyme electrodes: analytical expression of current density for varying potential.

Kirthiga, M.; Rajendran, L.; Fernandez, C.

Abstract

We present for the first time a mathematical model of osmium redox polymer mediated glucose oxidase enzyme electrodes. This model is based on a system of three coupled nonlinear reaction-diffusion equations under steady-state conditions for biochemical reactions occurring in the biofuel cells that describes the oxidized mediator, oxygen and substrate (Glucose) concentration within the biofuel cell. Simple analytical expressions for the concentration of oxidized mediator, oxygen and substrate and the corresponding current-potential response have been derived for all the values of reaction diffusion parameters using the new homotopy perturbation method (NHPM).The current-potential response in osmium redox polymer mediated glucose oxidase enzyme electrodes is discussed. The analytical results for the concentrations are also compared with numerical results and a satisfactory agreement is noted. The influence of diffusion coefficient of mediator, thickens of the film, turnover rate of Gluocose Oxidase and Michaelis-Menten constant on current-potential curve is also analyzed.

Citation

KIRTHIGA, M., RAJENDRAN, L. and FERNANDEZ, C. 2017. Theoretical treatment of diffusion and kinetics of osmium redox polymer mediated glucose oxidase enzyme electrodes: analytical expression of current density for varying potential. Electrochimica acta [online], 230, pages 89-97. Available from: https://doi.org/10.1016/j.electacta.2017.01.149

• Journal Article Type: Article
• Acceptance Date: Jan 23, 2017
• Online Publication Date: Jan 24, 2017
• Publication Date: Mar 10, 2017
• Deposit Date: Feb 22, 2018
• Publicly Available Date: Feb 22, 2018
• Journal: Electrochimica acta
• Print ISSN: 0013-4686
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 230
• Pages: 89-97
• DOI: https://doi.org/10.1016/j.electacta.2017.01.149
• Keywords: Mathematical modeling; Biofuel; Osmium redox polymer; Nonlinear reaction diffusion equation; Glucose oxidase enzyme electrodes
• Public URL: http://hdl.handle.net/10059/2776