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Sequence variation in multidrug-resistant plasmid pLUH01, isolated from human nasopharyngeal swabs.

Atkinson, Kate V.; Bishop, Lisa A.; Rhodes, Glenn; Salez, Nicolas; McEwan, Neil R.; Hegarty, Matthew J.; Robey, Julie; Harding, Nicola; Wetherell, Simon; Lauder, Robert M.; Pickup, Roger W.; Wilkinson, Mark; Gatherer, Derek

Authors

Kate V. Atkinson

Lisa A. Bishop

Glenn Rhodes

Nicolas Salez

Neil R. McEwan

Matthew J. Hegarty

Julie Robey

Nicola Harding

Simon Wetherell

Robert M. Lauder

Roger W. Pickup

Mark Wilkinson

Derek Gatherer



Abstract

Three variants of the multidrug-resistant plasmid pLUH01 were assembled by deep sequencing from nasopharyngeal swabs. All have a 21-bp deletion in the RS14515 hypothetical gene. Variants 1 through 3 have 2, 6, and 3 nucleotide substitutions, respectively, compared to the pLUH01 reference genome. We named the new plasmid variants pLUH01/Lancaster/2015/1 to pLUH01/Lancaster/2015/3.

Journal Article Type Article
Publication Date Jul 31, 2018
Journal Microbiology resource announcements
Electronic ISSN 2576-098X
Publisher American Society for Microbiology
Peer Reviewed Peer Reviewed
Volume 7
Issue 1
Article Number 00835-18
Institution Citation ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2018. Sequence variation in multidrug-resistant plasmid pLUH01, isolated from human nasopharyngeal swabs. Microbiology resource announcements [online], 7(1), article number 00835-18. Available from: https://doi.org/10.1128/MRA.00835-18
DOI https://doi.org/10.1128/MRA.00835-18
Keywords Variants; Multi drug resistant plasmid pLUH01; Deep sequencing; Lancaster

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