A novel method of producing microbubbles for targeted drug delivery.
Peter K.J. Robertson
Microbubbles, currently employed in diagnostic ultrasound as a contrast agent, have a potential new application as vehicles for targeted drug delivery, which could revolutionise medicine by eliminating side-effects. A new device is developed which outperforms all existing devices in terms of minimum microbubble size:channel diameter ratio. A numerical model is established to describe the flow behaviour and it is determined that the flow regime and resulting microbubble size are dependent on the ratio of inner- to outer Weber number.
|Publication Date||Jan 1, 2016|
|Institution Citation||FIABANE, J. 2016. A novel method of producing microbubbles for targeted drug delivery. Robert Gordon University, PhD thesis.|
|Keywords||Microfluidics; Microbubbles; Drug delivery; Jet breakup; Turbulence; Weber number; CFD; Fluent|
FIABANE 2016 A novel method of producing microbubbles
Copyright: the author and Robert Gordon University