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A novel method of producing microbubbles for targeted drug delivery.

Fiabane, Joe

Authors

Joe Fiabane



Contributors

Ketan Pancholi
Supervisor

Paul Prentice
Supervisor

Iain Steel
Supervisor

Peter K.J. Robertson
Supervisor

Abstract

Microbubbles, currently employed in diagnostic ultrasound as a contrast agent, have a potential new application as vehicles for targeted drug delivery, which could revolutionise medicine by eliminating side-effects. A new device is developed which outperforms all existing devices in terms of minimum microbubble size:channel diameter ratio. A numerical model is established to describe the flow behaviour and it is determined that the flow regime and resulting microbubble size are dependent on the ratio of inner- to outer Weber number.

Thesis Type Thesis
Publication Date Jan 1, 2016
Institution Citation FIABANE, J. 2016. A novel method of producing microbubbles for targeted drug delivery. Robert Gordon University, PhD thesis.
Keywords Microfluidics; Microbubbles; Drug delivery; Jet breakup; Turbulence; Weber number; CFD; Fluent

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FIABANE 2016 A novel method of producing microbubbles (12.6 Mb)
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Copyright Statement
Copyright: the author and Robert Gordon University





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