Joe Fiabane
A novel method of producing microbubbles for targeted drug delivery.
Fiabane, Joe
Authors
Contributors
Dr Ketan Pancholi k.pancholi2@rgu.ac.uk
Supervisor
Paul Prentice
Supervisor
Iain Steel
Supervisor
Peter K.J. Robertson
Supervisor
Abstract
Microbubbles, currently employed in diagnostic ultrasound as a contrast agent, have a potential new application as vehicles for targeted drug delivery, which could revolutionise medicine by eliminating side-effects. A new device is developed which outperforms all existing devices in terms of minimum microbubble size:channel diameter ratio. A numerical model is established to describe the flow behaviour and it is determined that the flow regime and resulting microbubble size are dependent on the ratio of inner- to outer Weber number.
Citation
FIABANE, J. 2016. A novel method of producing microbubbles for targeted drug delivery. Robert Gordon University, PhD thesis.
| Thesis Type | Thesis |
|---|---|
| Publication Date | Jan 1, 2016 |
| Deposit Date | Aug 17, 2016 |
| Publicly Available Date | Aug 17, 2016 |
| Keywords | Microfluidics; Microbubbles; Drug delivery; Jet breakup; Turbulence; Weber number; CFD; Fluent |
| Public URL | http://hdl.handle.net/10059/1579 |
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FIABANE 2016 A novel method of producing microbubbles
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Publisher Licence URL
https://creativecommons.org/licenses/by-nc-nd/4.0/
Copyright Statement
Copyright: the author and Robert Gordon University