Knee flexion range of motion does not influence muscle hypertrophy of the quadriceps femoris during leg press training in resistance-trained individuals.

Larsen, Stian; Wolf, Milo; Schoenfeld, Brad J.; Sandberg, Nordis Ø.; Fredriksen, Andrea B.; Kristiansen, Benjamin S.; van den Tillaar, Roland; Swinton, Paul A.; Falch, Hallvard N.

Abstract

This study investigated the effect of knee flexion range of motion (ROM) during the leg press exercise on quadriceps femoris muscle hypertrophy in resistance-trained individuals. Twenty-three participants (training age: 7.2 ± 3.5 years) completed a within-participant design, performing four sets of unilateral leg presses to momentary failure twice weekly for eight weeks. In one leg, knee flexion range of motion (ROM) was fixed at approximately 5–100°, while for the other leg, participants used their maximum individualized ROM (5–154 ± 7.8°). Quadriceps muscle thickness was assessed via B-mode ultrasonography at the proximal, central, and distal regions of the mid- and lateral thigh. Bayesian analyses were conducted to quantify treatment effects and provide inferential estimates using credible intervals and Bayes Factors (BF). Univariate and multivariate analyses indicated "moderate" (BF = 0.14 to 0.22) and "extreme" (BF<0.01) evidence in support of the null hypothesis, respectively. Within-condition analyses revealed small-to-medium hypertrophic adaptations in both conditions, with absolute increases ranging from 1.08 mm to 1.91 mm. These findings suggest that both knee flexion ROMs are similarly effective for promoting quadriceps femoris muscle hypertrophy over a relatively short training-period in resistance-trained individuals.

Citation

LARSEN, S., WOLF, M., SCHOENFELD, B.J., SANDBERG, N.Ø., FREDRIKSEN, A.B., KRISTIANSEN, B.S., VAN DEN TILLAAR, R., SWINTON, P.A. and FALCH, H.N. [2025]. Knee flexion range of motion does not influence muscle hypertrophy of the quadriceps femoris during leg press training in resistance-trained individuals. Journal of sports sciences [online], Latest Articles. Available from: https://doi.org/10.1080/02640414.2025.2481534

• Journal Article Type: Article
• Acceptance Date: Mar 12, 2025
• Online Publication Date: Mar 20, 2025
• Deposit Date: Mar 13, 2025
• Publicly Available Date: Mar 21, 2026
• Journal: Journal of sports sciences
• Print ISSN: 0264-0414
• Electronic ISSN: 1466-447X
• Publisher: Taylor and Francis
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1080/02640414.2025.2481534
• Keywords: Muscle length; Knee extensors; Resistance training; Ultrasonography; Regional hypertrophy
• Public URL: https://rgu-repository.worktribe.com/output/2748835
• Related Public URLs: https://rgu-repository.worktribe.com/output/2782611 (Supplementary material associated with this output)