Semaglutide for weight loss.

Ojeniran, Mo; Dube, Betty; Paige, Allison; Ton, Joey; Lindblad, Adrienne J.

Abstract

Is semaglutide (SGT) effective for weight loss? Used with lifestyle changes, 2.4 mg of subcutaneous SGT weekly resulted in a mean 10% to 15% weight loss (10 to 15 kg) over 68 weeks versus 2% to 3% (3 to 4 kg) with placebo (PC). Most (70% to 80%) lost 5% or more of their body weight. About 75% had gastro-intestinal side effects, but few discontinued treatment. Weight was regained on medication discontinuation.

Citation

OJENIRAN, M., DUBE, B., PAIGE, A., TON, J. and LINDBLAD, A.J. 2021. Semaglutide for weight loss. Canadian family physician [online], 67(11), page 842. Available from: https://doi.org/10.46747/cfp.6711842

• Journal Article Type: Article
• Acceptance Date: Nov 12, 2021
• Online Publication Date: Nov 12, 2021
• Publication Date: Nov 30, 2021
• Deposit Date: Mar 31, 2025
• Publicly Available Date: Apr 15, 2025
• Journal: Canadian family physician
• Print ISSN: 0008-350X
• Electronic ISSN: 1715-5258
• Publisher: College of Family Physicians of Canada (CFPC)
• Peer Reviewed: Peer Reviewed
• Volume: 67
• Issue: 11
• Pages: 842
• DOI: https://doi.org/10.46747/cfp.6711842
• Keywords: Lifestyle changes; Weight loss; Semaglutide (SGT)
• Public URL: https://rgu-repository.worktribe.com/output/2767907