Use of CYP1B1 inhibitors for treating cancer.

Murray, Graeme Ian; Melvin, William Thomas; McFadyen, Morag

Abstract

CYP1B1 proteins and their role in metabolising or inactivating anti-cancer drugs are disclosed, together with compositions for treating cancer comprising a substance capable of inhibiting CYP1B1 protein and an anti-cancer drug (e.g. docetaxel, paclitaxel, flutamide, tamoxifen, mitoxantrone, doxorubicin or daunomycin).

Citation

MURRAY, G.I., MELVIN, W.T. and MCFADYEN, M. 2001. Use of CYP1B1 inhibitors for treating cancer. International patent application PCT/GB2001/000548. International publication number WO/2001/058444 (WO 01/58444 A1), published 16.08.2001. Available from: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2001058444

• Publication Date: Aug 16, 2001
• Deposit Date: Sep 8, 2020
• Publicly Available Date: Sep 8, 2020
• Keywords: Cytochrome P450; CYP1B1; Cancer treatments
• Public URL: https://rgu-repository.worktribe.com/output/966541
• Additional Information: Publication number WO/2001/058444 (WO 01/58444 A1). Also published as Australian Patent Office AU2001232060; Canadian Patent Office CA2399402; European Patent Office EP1261332; Japanese Patent Office JP2003522143; US Patent and Trademarks Office US20030162727.