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Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. (2017)
Journal Article
TURNER, A.D., WAACK, J., LEWIS, A., EDWARDS, C. and LAWTON, L. 2018. Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders. Journal of chromatography B [online], 1074-1075, pages 111-123. Available from: https://doi.org/10.1016/j.jchromb.2017.12.032

A simple, rapid UHPLC-MS/MS method has been developed and optimised for the quantitation of microcystins and nodularin in wide variety of sample matrices. Microcystin analogues targeted were MC-LR, MC-RR, MC-LA, MC-LY, MC-LF, LC-LW, MC-YR, MC-WR, [As... Read More about Development and single-laboratory validation of a UHPLC-MS/MS method for quantitation of microcystins and nodularin in natural water, cyanobacteria, shellfish and algal supplement tablet powders..

A photocatalytic impeller reactor for gas phase heterogeneous photocatalysis. (2017)
Journal Article
TOKODE, O., PRABHU, R., LAWTON, L.A. and ROBERTSON, P.K.J. 2017. A photocatalytic impeller reactor for gas phase heterogeneous photocatalysis. Journal of environmental chemical engineering [online], 5(4), pages 3942-3948. Available from: https://doi.org/10.1016/j.jece.2017.07.068

A novel photocatalytic reactor based on a stirred tank configuration has been described. This reactor employs the use of photocatalytic impellers to aid the mass transport of gaseous organic compounds during photocatalytic reactions. Experiments invo... Read More about A photocatalytic impeller reactor for gas phase heterogeneous photocatalysis..

Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. (2017)
Thesis
WAACK, J. 2017. Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis. Robert Gordon University, PhD thesis.

Cyanobacteria produce a variety of secondary metabolites that possess - amongst other things - antifungal, antibacterial and antiviral properties. Being primary producers, they are also a vital component within the food web. However, certain strains... Read More about Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis..

Energy efficient operation of photocatalytic reactors based on UV LEDs for pollution remediation in water. (2017)
Presentation / Conference Contribution
PRABHU, R., HEWITT, F., GEORGIEVA, G., MEENAKSHI, H.N., LAWTON, L.A. and ROBERTSON, P.K.J. 2017. Energy efficient operation of photocatalytic reactors based on UV LEDs for pollution remediation in water. In Proceedings of OCEANS 2017, 19-22 June 2017, Aberdeen, UK. New York: IEEE [online], article number 8085011, pages 2623-2627. Available from: https://doi.org/10.1109/OCEANSE.2017.8085011

Photocatalytic technology using TiO2 is one of the emerging approaches for water treatment, especially as a final step to remove complex organics such as pesticides, hormones or humic acids. Titanium dioxide (TiO2) is a semiconductor material with st... Read More about Energy efficient operation of photocatalytic reactors based on UV LEDs for pollution remediation in water..

Cellulose II as bioethanol feedstock and its advantages over native cellulose. (2017)
Journal Article
NAGARAJAN, S., SKILLEN, N.C., IRVINE, J.T.S, LAWTON, L.A. and ROBERTSON, P.K. 2017. Cellulose II as bioethanol feedstock and its advantages over native cellulose. Renewable and sustainable energy reviews [online], 77, pages 182-192. Available from: https://doi.org/10.1016/j.rser.2017.03.118

Alternative renewable energy must emerge to sustainably meet the energy demands of the present and future. Current alternatives to fossil fuels are electricity from solar, wind and tidal energies and biofuels. Biofuels, especially bioethanol could be... Read More about Cellulose II as bioethanol feedstock and its advantages over native cellulose..

Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66. (2017)
Journal Article
HAMEED, S., LAWTON, L.A., EDWARDS, C., KHAN, A., FAROOQ, U. and KHAN, F.A. 2017. Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66. Journal of applied phycology [online], 29(4), pages 1801-1810. Available from: https://doi.org/10.1007/s10811-017-1115-5

Nodularia spumigena is one of the dominant toxic cyanobacteria which produce blooms in the Baltic Sea, a brackish water body, particularly in late summer. Nodularia spp. are known to produce hepatotoxic nodularins (NODs) and other bioactive peptides... Read More about Effects of temperature and salinity on the production of cell biomass, chlorophyll-a and intra- and extracellular nodularins (NOD) and nodulopeptin 901 produced by Nodularia spumigena KAC 66..

Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana. (2017)
Journal Article
ADDICO, G.N.D., LAWTON, L. and EDWARDS, C. 2017. Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana. Toxicology and forensic medicine [online], 2(1), pages 1-11. Available from: https://doi.org/10.17140/TFMOJ-2-111

Background: Microcystins are cyclic peptides containing seven amino acids with the condensation of two terminal amino acids of the linear peptide to form a cyclic compound. The cyclic nature of microcystins suggests that they are highly stable in wat... Read More about Hepatotoxic-microcystins in two drinking water reservoirs in the central region of Ghana..

Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides. (2017)
Journal Article
PHOTOS-JONES, E., EDWARDS, C., HANER, F., LAWTON, L., KEAN, C., LEANORD, A. and PERDIKATSIS, V. 2017. Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides. Geological society: special publications. Geology and medicine: historical connections [online], 452, pages 141-153. Available from: https://doi.org/10.1144/SP452.6

This paper presents the scientific investigation of three Lemnian sphragides (terra sigillata), a famed medicinal clay (earth) of antiquity, dated to the 16th-17th century, and presently in the collection of the Museum for the History of Pharmacy of... Read More about Archaeological medicinal earths as antibacterial agents: the case of the Basel Lemnian sphragides..

Mixing regime simulation and cellulose particle tracing in a stacked frame photocatalytic reactor. (2016)
Journal Article
NAGARAJAN, S., STELLA, L., LAWTON, L.A., IRVINE, J.T.S. and ROBERTSON, P.K.J. 2017. Mixing regime simulation and cellulose particle tracing in a stacked frame photocatalytic reactor. Chemical engineering journal [online], 313, pages 301-308. Available from: https://doi.org/10.1016/j.cej.2016.12.016

To sustainably meet the global energy demand, unconventional methods to produce renewable energy must emerge. Biofuels from cellulose (via fermentable sugar production) mediated via photocatalysis provides an alternative to conventional fossil fuels.... Read More about Mixing regime simulation and cellulose particle tracing in a stacked frame photocatalytic reactor..

Comparative assessment of visible light and UV active photocatalysts by hydroxyl radical quantification. (2016)
Journal Article
NAGARAJAN, S., SKILLEN, N.C., FINA, F., ZHANG, G., RANDORN, C., LAWTON, L.A., IRVINE, J.T.S. and ROBERTSON, P.K.J. 2016. Comparative assessment of visible light and UV active photocatalysts by hydroxyl radical quantification. Journal of photochemistry and photobiology A: chemistry [online], 334, pages 13-19. Available from: https://doi.org/10.1016/j.jphotochem.2016.10.034

A simple method for determining hydroxyl radical yields on semiconductor photocatalysts is highly desirable, especially when comparing different photocatalyst materials. This paper reports the screening of a selection of visible light active photocat... Read More about Comparative assessment of visible light and UV active photocatalysts by hydroxyl radical quantification..

Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans. (2016)
Thesis
KREITZ, J. 2016. Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans. Robert Gordon University, MPhil thesis.

Bacterial bioremediation has been proposed as an efficient, low cost and ecologically safe method to clean vital water reservoirs from cyanobacterial peptide toxins microcystins (MCs). In previous work carried out in 2008 several bacteria were isolat... Read More about Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans..

Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors. (2016)
Journal Article
LANCE, E., DESPRAT, J., HOLBECH, B.F., GERARD, C., BORMANS, M., LAWTON, L.A., EDWARDS, C. and WIEGAND, C. 2016. Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors. Aquatic toxicology [online], 177, pages 116-124. Available from: https://doi.org/10.1016/j.aquatox.2016.05.024

Freshwater gastropods are increasingly exposed to multiple stressors in the field such as the herbicide glyphosate in Roundup formulations and cyanobacterial blooms either producing or not producing microcystins (MCs), potentially leading to interact... Read More about Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors..

Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. (2016)
Journal Article
DELGADO-BAQUERIZO, M., GIARAMIDA, L., REICH, P.B., KHACHANE, A.N., HAMONTS, K., EDWARDS, C., LAWTON, L.A. and SINGH, B.K. 2016. Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. Journal of ecology [online], 104(4), pages 936-946. Available from: https://doi.org/10.1111/1365-2745.12585

1. Biodiversity is declining worldwide with detrimental effects on ecosystems. However, we lack a quantitative understanding of the shape of the relationship between microbial biodiversity and ecosystem function (BEF). This limits our understanding o... Read More about Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning..

An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806. (2016)
Thesis
ARIF ABDUL RAHMAN, T. 2016. An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806. Robert Gordon University, PhD thesis.

Cyanobacteria are one of the oldest forms of photosynthetic life and may have contributed significantly to the evolution of oxygen into the then anoxic environment. Cyanobacteria are also one of the best sources of natural secondary metabolites (cyan... Read More about An investigation on the effects of cyanopeptides on the growth and secondary metabolite production of Microcystis aeruginosa PCC7806..

Controlled periodic illumination in semiconductor photocatalysis. (2015)
Journal Article
TOKODE, O., PRABHU, R., LAWTON, L.A. and ROBERTSON, P.K.J. 2015. Controlled periodic illumination in semiconductor photocatalysis. Journal of photochemistry and photobiology A: chemistry [online], 319-320, pages 96-106. Available from: https://doi.org/10.1016/j.jphotochem.2015.12.002

Controlled periodic illumination is a hypothesis postulated in the early 1990s for enhancing the efficiency of semiconductor photocatalytic reactions. This technique has been proposed to improve photocatalytic efficiency by the nature of photon intro... Read More about Controlled periodic illumination in semiconductor photocatalysis..

Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photcatalysis. (2015)
Journal Article
ZHANG, G., NI, C., HUANG, X., WELGARMAGE, A., LAWTON, L.A., ROBERTSON, P.K.J. and IRVINE, J.T.S. 2016. Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photcatalysis. Chemical communications [online], 52, pages 1673-1676. Available from: https://doi.org/10.1039/c5cc09075j

Photocatalytic conversion of cellulose to sugars and carbon dioxide with simultaneous production of hydrogen assisted by cellulose decomposition under UV or solar light irradiation was achieved upon immobilization of cellulose onto a TiO2 photocataly... Read More about Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photcatalysis..

Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq. (2015)
Journal Article
KHURRAM, M., LAWTON, L.A., EDWARDS, C., IRITI, M., HAMEED, A., KHAN, M.A., KHAN, F.A. and RAHMAN, S.U. 2015. Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq. International journal of molecular science [online], 16(9), pages 20290-20307. Available from: https://doi.org/10.3390/ijms160920290

Plant extracts are complex matrices and, although crude extracts are widely in use, purified compounds are pivotal in drug discovery. This study describes the application of automated preparative-HPLC combined with a rapid off-line bacterial bioassay... Read More about Rapid bioassay-guided isolation of antibacterial clerodane type diterpenoid from Dodonaea viscosa (L.) Jaeq..

Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres. (2015)
Journal Article
PESTANA, C.J., EDWARDS, C., PRABHU, R., ROBERTSON, P.K.J. and LAWTON, L.A. 2015. Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres. Journal of hazardous materials [online], 300, pages 347-353. Available from: https://doi.org/10.1016/j.jhazmat.2015.07.016

Microcystins and nodularin are toxic cyanobacterial secondary metabolites produced by cyanobacteria that pose a threat to human health in drinking water. Conventional water treatment methods often fail to remove these toxins. Advanced oxidation proce... Read More about Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres..

Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. (2014)
Thesis
MCGEE, D. 2014. Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. Robert Gordon University, MRes thesis.

The marine amphipod Corophium volutator is an important source of food for many fish and wading birds, making it an important species in an estuarine environment and a relevant toxicological test species. Historical data has indicated that seasonal v... Read More about Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens..

Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria. (2014)
Presentation / Conference Contribution
MINAS, K., KARUNAKARAN, E., BOND, T., GANDY, C., HONSBEIN, A., MADSEN, M., AMEZAGA, J., AMTMANN, A., TEMPLETON, M.R., BIGGS, C.A. and LAWTON, L. 2015. Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria. Desalination and water treatment [online], 55(10): selected papers presented at 2015 Desalination for the environment conference: clean water and energy, 11-15 May 2014, Limassol, Cyprus, pages 2647-2668. Available from: https://doi.org/10.1080/19443994.2014.940647

Although desalination by membrane processes is a possible solution to the problem of freshwater supply, related cost and energy demands prohibit its use on a global scale. Hence, there is an emerging necessity for alternative, energy and cost-efficie... Read More about Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria..