All Outputs (40)

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: implications for exercise training and prescription. (2020)
Journal Article
NICHOLS, S., O'DOHERTY, A., CARROLL, S. and INGLE, L. 2020. Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: implications for exercise training and prescription. European journal of preventive cardiology [online], 27(9), pages 1001-1003. Available from: https://doi.org/10.1177/2047487319856432

The metabolic equivalent (MET) is a widely used physiological concept for quantifying levels of habitual physical activity and cardiorespiratory fitness (CRF). The MET conveys the oxygen consumption requirements of physical activities as multiples of... Read More about Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: implications for exercise training and prescription..

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective. (2020)
Journal Article
PYMER, S., NICHOLS, S., PROSSER, J., BIRKETT, S., CARROLL, S. and INGLE, L. 2020. Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective. European journal of preventive cardiology [online], 27(6), pages 579-589. Available from: https://doi.org/10.1177/2047487319852711

In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve (%HRR)) in cardiac rehabilitation programmes. We aimed to determine the accuracy of this approach by comparing it with an objective, thre... Read More about Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? A United Kingdom perspective..

Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study. (2020)
Journal Article
NICHOLS, S., TAYLOR, C., GOODMAN, T., PAGE, R., KALLVIKBACKA-BENNETT, A., NATION, F., CLARK, A.L., BIRKETT, S.T., CARROLL, S. and INGLE, L. 2020. Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study. International journal of cardiology [online], 305, pages 25-34. Available from: https://doi.org/10.1016/j.ijcard.2020.01.044

Recent evidence suggests that routine exercise-based cardiac rehabilitation (CR) may not lead to a substantial increase in estimated peak oxygen uptake (VO2peak). This could reduce the potential benefits of CR and explain why CR no longer improves pa... Read More about Routine exercise-based cardiac rehabilitation does not increase aerobic fitness: a CARE CR study..

Feasibility study of early outpatient review and early cardiac rehabilitation after cardiac surgery: mixed-methods research design: a study protocol. [Protocol] (2019)
Other
NGAAGE, D., MITCHELL, N., DEAN, A., HIRST, C., AKOWUAH, E., DOHERTY, P.J., FAIRHURST, C., FLEMMING, K., HEWITT, C., HINDE, S., MITCHELL, A., NICHOLS, S. and WATSON, J. 2019. Feasibility study of early outpatient review and early cardiac rehabilitation after cardiac surgery: mixed-methods research design: a study protocol. [Protocol]. BMJ open [online], 9(12), article number e035787. Available from: https://doi.org/10.1136/bmjopen-2019-035787

Following cardiac surgery, patients currently attend an outpatient review 6 weeks after hospital discharge, where recovery is assessed and suitability to commence cardiac rehabilitation (CR) is determined. CR is then started from 8 weeks. Following a... Read More about Feasibility study of early outpatient review and early cardiac rehabilitation after cardiac surgery: mixed-methods research design: a study protocol. [Protocol].

The effect of protein and essential amino acid supplementation on muscle strength and performance in patients with chronic heart failure: a systematic review. (2019)
Journal Article
NICHOLS, S., MCGREGOR, G., AL-MOHAMMAD, A., ALI, A.N., TEW, G. and O'DOHERTY, A.F. 2020. The effect of protein and essential amino acid supplementation on muscle strength and performance in patients with chronic heart failure: a systematic review. European journal of nutrition [online], 59(5), pages 1785-1801. Available from: https://doi.org/10.1007/s00394-019-02108-z

Critically low skeletal muscle mass and strength, observed in 20% of people with chronic heart failure (CHF), reduces functional capacity, quality of life (QoL) and survival. Protein and essential amino acid (EAA) supplementation could be a viable tr... Read More about The effect of protein and essential amino acid supplementation on muscle strength and performance in patients with chronic heart failure: a systematic review..

Exercise training as a mediator for enhancing coronary collateral circulation: a review of the evidence. (2019)
Journal Article
NICKOLAY, T., NICHOLS, S., INGLE, L. and HOYE, A. 2020. Exercise training as a mediator for enhancing coronary collateral circulation: a review of the evidence. Current cardiology reviews [online], 16(3), pages 212-220. Available from: http://dx.doi.org/10.2174/1573403X15666190819144336

Coronary collateral vessels supply blood to areas of myocardium at risk after arterial occlusion. Flow through these channels is driven by a pressure gradient between the donor and the occluded artery. Concomitant with increased collateral flow is an... Read More about Exercise training as a mediator for enhancing coronary collateral circulation: a review of the evidence..

Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: a United Kingdom perspective. (2019)
Journal Article
KHUSHHAL, A., NICHOLS, S., CARROLL, S., ABT, G. and INGLE, L. 2019. Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: a United Kingdom perspective. PLoS ONE [online], 14(6), article number e0217654. Available from: https://doi.org/10.1371/journal.pone.0217654

In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified. We were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the variability in the effect... Read More about Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: a United Kingdom perspective..

The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake. (2019)
Journal Article
BIRKETT, S.T., NICHOLS, S., SAWREY, R., GLEADALL-SIDDALL, D., MCGREGOR, G. and INGLE, L. 2019. The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake. Sport sciences for health (online), 15(2), pages 443-451. Available from: https://doi.org/10.1007/s11332-019-00552-2

High-intensity interval training (HIIT) and circuit training (CT) are popular methods of exercise, eliciting improvements in cardiorespiratory fitness (CRF). However, direct comparisons of these two training methods are limited. We investigated the e... Read More about The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake..

Correction to Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. (2019)
Journal Article
NICHOLS, S., TAYLOR, C., PAGE, R., KALLVIKBACKA-BENNETT, A., NATION, F., GOODMAN, T., CLARK, A.L., CARROLL, S. and INGLE, L. 2019. Correction to Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports medicine - open [online], 5, article number 5. Available from: https://doi.org/10.1186/s40798-019-0179-y

This correction addresses an error in Table 4 of the original article.

Exercise rehabilitation programmes for pulmonary hypertension: a systematic review of intervention components and reporting quality. (2018)
Journal Article
MCGREGOR, G., POWELL, R., FINNEGAN, S., NICHOLS, S. and UNDERWOOD, M. 2018. Exercise rehabilitation programmes for pulmonary hypertension: a systematic review of intervention components and reporting quality. BMJ open sport and exercise medicine [online], 4(1), article number e000400. Available from: https://doi.org/10.1136/bmjsem-2018-000400

The aim of this study was to identify the components, and assess the reporting quality, of exercise training interventions for people living with pulmonary hypertension. The study took the form of a systematic review with analysis of intervention rep... Read More about Exercise rehabilitation programmes for pulmonary hypertension: a systematic review of intervention components and reporting quality..

Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease: a CARE CR study. (2018)
Journal Article
NICHOLS, S., O'DOHERTY, A.F., TAYLOR, C., CLARK, A.L., CARROLL, S. and INGLE, L. 2019. Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease: a CARE CR study. Clinical physiology and functional imaging [online], 39(1), pages 93-102. Available from: https://doi.org/10.1111/cpf.12539

In patients with chronic heart failure, there is a positive linear relationship between skeletal muscle mass (SMM) and peak oxygen consumption (VO2peak); an independent predictor of all-cause mortality. We investigated the association between SMM and... Read More about Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease: a CARE CR study..

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. (2018)
Journal Article
NICHOLS, S., TAYLOR, C., PAGE, R., KALLVIKBACKA-BENNETT, A., NATION, F., GOODMAN, T., CLARK, A.L., CARROLL, S. and INGLE, L. 2018. Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports medicine - open [online], 4, article number 22. Available from: https://doi.org/10.1186/s40798-018-0138-z

Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabolic risk factor profile may be resp... Read More about Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study..

CARE CR: cardiovascular and cardiorespiratory adaptations to routine exercise-based cardiac rehabilitation: a study protocol for a community-based controlled study with criterion methods. [Protocol] (2018)
Other
NICHOLS, S., NATION, F., GOODMAN, T., CLARK, A.L., CARROLL, S. and INGLE, L. 2018. CARE CR: cardiovascular and cardiorespiratory adaptations to routine exercise-based cardiac rehabilitation: a study protocol for a community-based controlled study with criterion methods. [Protocol]. BMJ open [online], 8(1), article number e019216. Available from: https://doi.org/10.1136/bmjopen-2017-019216

Cardiac rehabilitation (CR) reduces all-cause and cardiovascular mortality in patients with coronary heart disease (CHD). Much of this improvement has been attributed to the beneficial effects of structured exercise training. However, UK-based studie... Read More about CARE CR: cardiovascular and cardiorespiratory adaptations to routine exercise-based cardiac rehabilitation: a study protocol for a community-based controlled study with criterion methods. [Protocol].

Validity and reliability of the Apple Watch for measuring heart rate during exercise. (2017)
Journal Article
KHUSHHAL, A., NICHOLS, S., EVANS, W., GLEADALL-SIDDALL, D.O., PAGE, R., O'DOHERTY, A.F., CARROLL, S., INGLE, L. and ABT, G. 2017. Validity and reliability of the Apple Watch for measuring heart rate during exercise. Sports medicine international open [online], 1(06), pages E206-E211. Available from: https://doi.org/10.1055/s-0043-120195

We examined the validity and reliability of the Apple Watch heart rate sensor during and in recovery from exercise. Twenty-one males completed treadmill exercise while wearing two Apple Watches (left and right wrists) and a Polar S810i monitor (crite... Read More about Validity and reliability of the Apple Watch for measuring heart rate during exercise..

Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? (2017)
Journal Article
NICHOLS, S., GLEADALL-SIDDALL, D.O., ANTONY, R., CLARK, A.L., CLELAND, J.G.F., CARROLL, S. and INGLE, L. 2018. Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? Clinical physiology and functional imaging [online], 38(4), pages 681-688. Available from: https://doi.org/10.1111/cpf.12468

Cardiopulmonary exercise testing (CPET) is the 'gold standard' method of determining VO2peak. When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equivalents (METs). Card... Read More about Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?.

High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. [Protocol] (2016)
Other
MCGREGOR, G., NICHOLS, S., HAMBORG, T. et al. 2016. High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. [Protocol]. BMJ open [online], 6(11), article number e012843. Available from: https://doi.org/10.1136/bmjopen-2016-012843

Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for coronary heart disease (C... Read More about High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. [Protocol].

National certification programme for cardiovascular rehabilitation: aiming to improve practice. (2016)
Journal Article
FURZE, G., NICHOLS, S., DOHERTY, P., HINTON, S., ILIFF, A. and MILLS, J. 2016. National certification programme for cardiovascular rehabilitation: aiming to improve practice. Perspectives in public health [online], 136(6), pages 318-320. Available from: https://doi.org/10.1177/1757913916668291

Cardiovascular disease (CVD) continues to be a leading cause of mortality and morbidity in the United Kingdom. It is also a leading contributor to health inequalities; reducing excess deaths from coronary heart disease in the most deprived fifth of a... Read More about National certification programme for cardiovascular rehabilitation: aiming to improve practice..

A clinician's guide to cardiopulmonary exercise testing 2: test interpretation. (2015)
Journal Article
NICHOLS, S., TAYLOR, C. and INGLE, L. 2015. A clinician's guide to cardiopulmonary exercise testing 2: test interpretation. British journal of hospital medicine [online], 76(5), pages 281-289. Available from: https://doi.org/10.12968/hmed.2015.76.5.281

Data obtained from cardiopulmonary exercise testing offer additional interpretive power over conventional exercise tolerance testing. When used correctly, these data allow improved clinical decision making in patients with cardiometabolic and respira... Read More about A clinician's guide to cardiopulmonary exercise testing 2: test interpretation..

A clinician's guide to cardiopulmonary exercise testing 1: an introduction. (2015)
Journal Article
TAYLOR, C., NICHOLS, S. and INGLE, L. 2015. A clinician's guide to cardiopulmonary exercise testing 1: an introduction. British journal of hospital medicine [online], 76(4), pages 192-195. Available from: https://doi.org/10.12968/hmed.2015.76.4.192

Compared to standard exercise tolerance testing, cardiopulmonary exercise testing is a reliable and powerful tool that can be used for risk stratification, exercise prescription and clinical diagnosis.

Variability of automated carotid intima-media thickness measurements by novice operators. (2014)
Journal Article
NICHOLS, S., MILNER, M., MEIJER, R., CARROLL, S. and INGLE, L. 2016. Variability of automated carotid intima-media thickness measurements by novice operators. Clinical physiology and functional imaging [online], 36(1), pages 25-32. Available from: https://doi.org/10.1111/cpf.12189

Carotid intima-media thickness (C-IMT) measurements provide a non-invasive assessment of subclinical atherosclerosis. The aim of the study was to assess the inter- and intra-observer variability of automated C-IMT measurements undertaken by two novic... Read More about Variability of automated carotid intima-media thickness measurements by novice operators..