All Outputs (833)

Characterisation of illicit ecstasy and diazepam tablets by colorant identification. (2018)
Journal Article
SHARRENBROCH, L., TOUGH, A. and MATTHEWS, K.H. 2018. Characterisation of illicit ecstasy and diazepam tablets by colorant identification. Analytical methods [online], 10(17), pages 2048-2055. Available from: https://doi.org/10.1039/c7ay02921g

Ecstasy and diazepam are two commonly abused drugs with a high potential for dependence. They are typically available as oral tablets that contain both the drug and other bulk components (excipients). Compositional knowledge of individual tablets off... Read More about Characterisation of illicit ecstasy and diazepam tablets by colorant identification..

A case study of polypharmacy management in nine European countries: implications for change management and implementation. (2018)
Journal Article
MCINTOSH, J., ALONSO, A., MACLURE, K., STEWART, D., KEMPEN, T., MAIR, A., CASTEL-BRANCO, M., CODINA, C., FERNANDEZ-LLIMOS, F., FLEMING, G., GENNIMATA, D., GILLESPIE, U., HARRISON, C., ILLARIO, M., JUNIUS-WALKER, U., KAMPOLIS, C.F., KARDAS, P., LEWEK, P., MALVA, J., MENDITTO, E., SCULLIN, C., WIESE, B. 2018. A case study of polypharmacy management in nine European countries: implications for change management and implementation. PLoS ONE [online], 13(4), article number e0195232. Available from: https://doi.org/10.1371/journal.pone.0195232

Background: - Multimorbidity and its associated polypharmacy contribute to an increase in adverse drug events, hospitalizations, and healthcare spending. This study aimed to address: what exists regarding polypharmacy management in the European Union... Read More about A case study of polypharmacy management in nine European countries: implications for change management and implementation..

A UK perspective on human factors and patient safety education in pharmacy curricula. (2018)
Journal Article
VOSPER, H. and HIGNETT, S. 2018. A UK perspective on human factors and patient safety education in pharmacy curricula. American journal of pharmaceutical education [online], 82(3), article number 6184. Available from: https://doi.org/10.5688/ajpe6184

Objective: - To take a systematic approach to exploring patient safety teaching in health care curricula, particularly in relation to how educators ensure students achieve patient safety competencies. Findings: - There is a lack of formally articulat... Read More about A UK perspective on human factors and patient safety education in pharmacy curricula..

Temperature effects explain continental scale distribution of cyanobacterial toxins. (2018)
Journal Article
MANTZOUKI, E., LÜRLING, M., FASTNER, J., DE SENERPONT DOMIS, L., IBELINGS, B.W., TEURLINCX, S. and CHMURA, D. 2018. Temperature effects explain continental scale distribution of cyanobacterial toxins. Toxins [online], 10(4), article number 156. Available from: https://doi.org/10.3390/toxins10040156

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other c... Read More about Temperature effects explain continental scale distribution of cyanobacterial toxins..

Nano-selenium and its nanomedicine applications: a critical review. (2018)
Journal Article
HOSNEDLOVA, B., KEPINSKA, M., SKALICKOVA, S., FERNANDEZ, C., RUTTKAY-NEDECKY, B., PENG, Q., BARON, M., MELCOVA, M., OPATRILOVA, R., ZIDKOVA, J., BJORKLUND, G., SOCHOR, J. and KIZEK, R. 2018. Nano-selenium and its nanomedicine applications: a critical review. International journal of nanomedicine [online], 13, pages 2107-2128. Available from: https://doi.org/10.2147/IJN.S157541

Traditional supplements of selenium generally have a low degree of absorption and increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of selenium compounds, which would raise the bioavailability of this eleme... Read More about Nano-selenium and its nanomedicine applications: a critical review..

Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. (2018)
Journal Article
PANDHAL, J., SISWANTO, A., KUVSHINOV, D., ZIMMERMAN, W.B., LAWTON, L. and EDWARDS, C. 2018. Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. Frontiers in microbiology [online], 9, article number 678. Available from: https://doi.org/10.3389/fmicb.2018.00678

There has been a steady rise in the global incidences of algal blooms and, worryingly, there is increasing evidence that changes in the global climate are leading to a shift toward cyanobacterial blooms. Many cyanobacterial genera are harmful, produc... Read More about Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation..

Overview of pharmacovigilance practices at the largest academic healthcare system in the State of Qatar. (2018)
Journal Article
AL HAIL, M., ELKASSEM, W., HAMAD, A., PALLIVALAPPILA, A., THOMAS, B. and STEWART, D. 2018. Overview of pharmacovigilance practices at the largest academic healthcare system in the State of Qatar. International journal of clinical pharmacy [online], 40(4), pages 769-774. Available from: https://doi.org/10.1007/s11096-018-0629-5

Adverse Drug Reactions (ADRs) are major global concern, adversely impacting patient safety and health outcomes. ADRs cause significant morbidity and mortality among hospitalised patients, causing greater length of hospital stay, increased healthcare... Read More about Overview of pharmacovigilance practices at the largest academic healthcare system in the State of Qatar..

Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages. (2018)
Journal Article
ALMPANIS, A., SWAIN, M., GATHERER, D. and MCEWAN, N. 2018. Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages. Microbial genomics [online], 4(4), article number 168. Available from: https://doi.org/10.1099/mgen.0.000168

Based on complete bacterial genome sequence data, we demonstrate a correlation between bacterial chromosome length and G+C content of the genome, with longer genomes having higher G+C contents. The correlation value decreases at shorter genome sizes... Read More about Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages..

Safety in healthcare: the pharmacy legislative framework and patient safety. (2018)
Journal Article
VOSPER, H. and HIGNETT, S.M. 2018. Safety in healthcare: the pharmacy legislative framework and patient safety. Journal of personal injury law [online], 1, pages 16-22. Available from: http://westlaw.co.uk

Considers how the legislative framework governing pharmaceuticals can have an impact on patient safety. Discusses key aspects of the healthcare system, the characteristics of a high reliability organisation (HRO), and the role of just culture. Examin... Read More about Safety in healthcare: the pharmacy legislative framework and patient safety..

Sophisticated construction of binary PdPb alloy nanocubes as robust electrocatalysts toward ethylene glycol and glycerol oxidation. (2018)
Journal Article
XU, H., SONG, P., FERNANDEZ, C., WANG, J., ZHU, M., SHIRAISHI, Y. and DU, Y. 2018. Sophisticated construction of binary PdPb alloy nanocubes as robust electrocatalysts toward ethylene glycol and glycerol oxidation. ACS applied materials and interfaces [online], 10(15), pages 12659-12665. Available from: https://doi.org/10.1021/acsami.8b00532

The design of nanocatalysts by controlling pore size and particle characteristics is crucial to enhance the selectivity and activity of the catalysts. Thus, we have successfully demonstrated the synthesis of binary PdPb alloy nanocubes (PdPb NCs) by... Read More about Sophisticated construction of binary PdPb alloy nanocubes as robust electrocatalysts toward ethylene glycol and glycerol oxidation..

Coronary vessel supersensitivity to noradrenaline in the presence of chronic sympathetic denervation. (2018)
Journal Article
DRAKE-HOLLAND, A.J. and NOBLE, M.I.M. 2018. Coronary vessel supersensitivity to noradrenaline in the presence of chronic sympathetic denervation. Journal of cardiac disorders and therapy [online], 1(1), article number 103. Available from: http://fulltext.scholarena.co/Coronary-Vessel-Supersensitivity-to-Noradrenaline-in-the-Presence-of-Chronic-Sympathetic-Denervation.php

It is well known that there is usually super-sensitivity to the normal neurotransmitter in chronically denervated organs. The present consensus of opinion is that there is no super-sensitivity of response of myocardial arteriolar resistance vessels t... Read More about Coronary vessel supersensitivity to noradrenaline in the presence of chronic sympathetic denervation..

Parasitized natural killer cells do not facilitate the spread of toxoplasma gondii to the brain. (2018)
Journal Article
PETIT-JENTREAU, L., GLOVER, C. and COOMBES, J.L. 2018. Parasitized natural killer cells do not facilitate the spread of toxoplasma gondiito the brain. Parasite immunology [online], 40(4), article e12522. Available from: https://doi.org/10.1111/pim.12522

Toxoplasmagondii is a protozoan parasite capable of invading immune cells and co-opting their migratory pathways to disseminate through the host. Natural Killer (NK) cells can be directly invaded by the parasite and this invasion alters NK cell migra... Read More about Parasitized natural killer cells do not facilitate the spread of toxoplasma gondii to the brain..

Usefulness of hair analysis and psychological tests for identification of alcohol and drugs of abuse consumption in driving license regranting. (2018)
Journal Article
LENDOIRO, E., DE CASTRO, A., JIMENEZ-MORIGOSA, C., GOMEZ-FRAGUELA, X.A., LOPEZ-RIVADULLA, M. and CRUZ, A. 2018. Usefulness of hair analysis and psychological tests for identification of alcohol and drugs of abuse consumption in driving license regranting. Forensic science international [online], 286, pages 239-244. Available from: https://doi.org/10.1016/j.forsciint.2018.03.023

Implementation of the points-based driving license has helped to change driver behavior, and can be linked to to a reduction of traffic accidents and fatalities. In Spain, a driving licence is revoked when all points are lost, and the driver must enr... Read More about Usefulness of hair analysis and psychological tests for identification of alcohol and drugs of abuse consumption in driving license regranting..

A nurse researcher's guide to reflexive interviewing. (2018)
Journal Article
LEAR, H., EBOH, W. and DIACK, L. 2018. A nurse researcher's guide to reflexive interviewing. Nurse researcher [online], 25(4), pages 35-42. Available from: https://doi.org/10.7748/nr.2018.e1550

Background: In a wider doctoral study related to unfavourable experiences of nursing students studying abroad, the researcher undertook a reflexive interview to reduce the potential for bias. Aim: To discuss a method for conducting reflexive intervie... Read More about A nurse researcher's guide to reflexive interviewing..

Knowledge and practice characteristics of pharmacists in Qatar towards medication use in pregnancy: a cross-sectional survey. (2018)
Journal Article
ABDUL ROUF, P., THOMAS, B., ELKASSEM, W., TARANNUM, A., AL SAAD, D., GASIM, M.M. and AL HAIL, M. 2018. Knowledge and practice characteristics of pharmacists in Qatar towards medication use in pregnancy: a cross-sectional survey. Eastern Mediterranean health journal [online], 24(2), pages 137-145. Available from: https://doi.org/10.26719/2018.24.2.137

Background: Medication use during pregnancy is common. Pharmacists have an important role in improving medication use during pregnancy. There is a lack of empirical evidence on pharmacists’ knowledge and practice characteristics towards medication us... Read More about Knowledge and practice characteristics of pharmacists in Qatar towards medication use in pregnancy: a cross-sectional survey..

Biotic phase micropollutant distribution in horizontal sub-surface flow constructed wetlands. (2018)
Journal Article
PETRIE, B., ROOD, S., SMITH, B.D., PROCTOR, K., YOUDAN, J., BARDEN, R., KASPRZYK-HORDERN, B. 2018. Biotic phase micropollutant distribution in horizontal sub-surface flow constructed wetlands. Science of the total environment [online], 630, pages 648-657. Available from: https://doi.org/10.1016/j.scitotenv.2018.02.242

The distribution of micropollutants in biotic phases of horizontal sub-surface flow (HSSF) constructed wetlands was investigated. 88 diverse micropollutants (personal care products, pharmaceuticals and illicit drugs) were monitored for in full-scale... Read More about Biotic phase micropollutant distribution in horizontal sub-surface flow constructed wetlands..

Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa. (2018)
Journal Article
O'DRISCOLL, N.H., CUSHNIE, T.P.T., MATTHEWS, K.H. and LAMB, A.J. 2018. Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of escherichia coli and pseudomonas aeruginosa. Archives of microbiology [online], 200(5), pages 793-802. Available from: https://doi.org/10.1007/s00203-018-1485-3

Whilst colistin (polymyxin E) represents the last mainstream treatment option for multi-drug resistant Gram-negative pathogens, details of its mechanism of action remain to be fully resolved. In this study, the effects of sub-inhibitory, inhibitory-b... Read More about Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa..

A novel safety anticipation estimation method for the aerial lithium-ion battery pack based on the real-time detection and filtering. (2018)
Journal Article
WANG, S., FERNANDEZ, C., CHEN, M., WANG, L. and SU, J. 2018. A novel safety anticipation estimation method for the aerial lithium-ion battery pack based on the real-time detection and filtering. Journal of cleaner production [online], 185, pages 187-197. Available from: https://doi.org/10.1016/j.jclepro.2018.01.236

Lithium-ion battery packs have become increasingly important for power supply applications, in which the state of charge estimation and output voltage tracking should be very critical for the safety protection. A novel real-time estimation method is... Read More about A novel safety anticipation estimation method for the aerial lithium-ion battery pack based on the real-time detection and filtering..

Relocating patients from a specialist homeless healthcare centre to general practices: a multi-perspective study. (2018)
Journal Article
GIBSON SMITH, K., PAUDYAL, V., MACLURE, K., FORBES-MCKAY, K., BUCHANAN, C., WILSON, L., MACLEOD, J., SMITH, A. and STEWART, D. 2018. Relocating patients from a specialist homeless healthcare centre to general practices: a multi-perspective study. British journal of general practice [online], 68(667), pages e105-e113. Available from: https://doi.org/10.3399/bjgp18X694577

Background: - The relocation of formerly homeless patients eligible to transfer from a specialist homeless healthcare centre (SHHC) to mainstream general practices is key to patient integration in the local community. Failure to transition patients c... Read More about Relocating patients from a specialist homeless healthcare centre to general practices: a multi-perspective study..

Inhibitors of trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease. (2018)
Journal Article
GASPAR, L., CORON, R.P., KONG THOO LIN, P., COSTA, D.M., PERES-CABEZAS, B., TAVARES, J., ROURA-FERRER, M., RAMOS, I., RONIN, C., MAJOR, L.L., CIESIELSKI, F., PEMBERTON, I.K., MACDOUGALL, J., CIAPETTI, P., SMITH, T.K. and CORDEIRO-DA-SILVA, A. 2018. Inhibitors of trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease. PLoS neglected tropical diseases [online], 12(1), article number e0006180. Available from: https://doi.org/10.1371/journal.pntd.0006180

Chagas disease remains one of the most neglected diseases in the world despite being the most important parasitic disease in Latin America. The characteristic chronic manifestation of chagasic cardiomyopathy is the region's leading cause of heart-rel... Read More about Inhibitors of trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease..