Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa.

O'Driscoll, No�lle H.; Cushnie, T.P. Tim; Matthews, Kerr H.; Lamb, Andrew J.

doi:10.1007/s00203-018-1485-3

Temperature effects explain continental scale distribution of cyanobacterial toxins. (2018)
Journal Article
MANTZOUKI, E., LÜRLING, M., FASTNER, J., DE SENERPONT DOMIS, L., IBELINGS, B.W., TEURLINCX, S. and CHMURA, D. 2018. Temperature effects explain continental scale distribution of cyanobacterial toxins. Toxins [online], 10(4), article number 156. Available from: https://doi.org/10.3390/toxins10040156

Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other c... Read More about Temperature effects explain continental scale distribution of cyanobacterial toxins..

Nano-selenium and its nanomedicine applications: a critical review. (2018)
Journal Article
HOSNEDLOVA, B., KEPINSKA, M., SKALICKOVA, S., FERNANDEZ, C., RUTTKAY-NEDECKY, B., PENG, Q., BARON, M., MELCOVA, M., OPATRILOVA, R., ZIDKOVA, J., BJORKLUND, G., SOCHOR, J. and KIZEK, R. 2018. Nano-selenium and its nanomedicine applications: a critical review. International journal of nanomedicine [online], 13, pages 2107-2128. Available from: https://doi.org/10.2147/IJN.S157541

Traditional supplements of selenium generally have a low degree of absorption and increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of selenium compounds, which would raise the bioavailability of this eleme... Read More about Nano-selenium and its nanomedicine applications: a critical review..

Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. (2018)
Journal Article
PANDHAL, J., SISWANTO, A., KUVSHINOV, D., ZIMMERMAN, W.B., LAWTON, L. and EDWARDS, C. 2018. Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation. Frontiers in microbiology [online], 9, article number 678. Available from: https://doi.org/10.3389/fmicb.2018.00678

There has been a steady rise in the global incidences of algal blooms and, worryingly, there is increasing evidence that changes in the global climate are leading to a shift toward cyanobacterial blooms. Many cyanobacterial genera are harmful, produc... Read More about Cell lysis and detoxification of cyanotoxins using a novel combination of microbubble generation and plasma microreactor technology for ozonation..

Overview of pharmacovigilance practices at the largest academic healthcare system in the State of Qatar. (2018)
Journal Article
AL HAIL, M., ELKASSEM, W., HAMAD, A., PALLIVALAPPILA, A., THOMAS, B. and STEWART, D. 2018. Overview of pharmacovigilance practices at the largest academic healthcare system in the State of Qatar. International journal of clinical pharmacy [online], 40(4), pages 769-774. Available from: https://doi.org/10.1007/s11096-018-0629-5

Adverse Drug Reactions (ADRs) are major global concern, adversely impacting patient safety and health outcomes. ADRs cause significant morbidity and mortality among hospitalised patients, causing greater length of hospital stay, increased healthcare... Read More about Overview of pharmacovigilance practices at the largest academic healthcare system in the State of Qatar..

Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages. (2018)
Journal Article
ALMPANIS, A., SWAIN, M., GATHERER, D. and MCEWAN, N. 2018. Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages. Microbial genomics [online], 4(4), article number 168. Available from: https://doi.org/10.1099/mgen.0.000168

Based on complete bacterial genome sequence data, we demonstrate a correlation between bacterial chromosome length and G+C content of the genome, with longer genomes having higher G+C contents. The correlation value decreases at shorter genome sizes... Read More about Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages..

Safety in healthcare: the pharmacy legislative framework and patient safety. (2018)
Journal Article
VOSPER, H. and HIGNETT, S.M. 2018. Safety in healthcare: the pharmacy legislative framework and patient safety. Journal of personal injury law [online], 1, pages 16-22. Available from: http://westlaw.co.uk

Considers how the legislative framework governing pharmaceuticals can have an impact on patient safety. Discusses key aspects of the healthcare system, the characteristics of a high reliability organisation (HRO), and the role of just culture. Examin... Read More about Safety in healthcare: the pharmacy legislative framework and patient safety..

Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences. (2018)
Thesis
HAIR, S.C. 2018. Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences. Robert Gordon University, PhD thesis.

Obesity has reached worldwide epidemic proportions and with this increased incidence of obesity, comes an increase in incidence of the comorbidities associated with obesity such as diabetes and cardiovascular disease (CVD). The underlying mechanisms... Read More about Determining the role of the LPI/GPR55 system in the development of obesity and associated cardiovascular consequences..

Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies. (2018)
Thesis
KOPSIDA, M. 2018. Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies. Robert Gordon University, PhD thesis.

Breast cancer is the most commonly occurring cancer in women, with incidence rates approaching 1.38 million cases per year worldwide. Over the last few decades, there have been numerous attempts to develop, synthesise and advance into the clinic nove... Read More about Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies..

An investigation and examination of the levels and types of bacterial contamination on the surface of clean room operators' garments. (2018)
Thesis
SMITH, L.M. 2018. An investigation and examination of the levels and types of bacterial contamination on the surface of clean room operators' garments. Robert Gordon University, PhD thesis.

The contamination of sterile pharmaceutical products is a serious event which has in the worst case scenario led to patient death. Operators are the primary source of clean room contamination, with the majority of their detritus being identified as s... Read More about An investigation and examination of the levels and types of bacterial contamination on the surface of clean room operators' garments..

Sophisticated construction of binary PdPb alloy nanocubes as robust electrocatalysts toward ethylene glycol and glycerol oxidation. (2018)
Journal Article
XU, H., SONG, P., FERNANDEZ, C., WANG, J., ZHU, M., SHIRAISHI, Y. and DU, Y. 2018. Sophisticated construction of binary PdPb alloy nanocubes as robust electrocatalysts toward ethylene glycol and glycerol oxidation. ACS applied materials and interfaces [online], 10(15), pages 12659-12665. Available from: https://doi.org/10.1021/acsami.8b00532

The design of nanocatalysts by controlling pore size and particle characteristics is crucial to enhance the selectivity and activity of the catalysts. Thus, we have successfully demonstrated the synthesis of binary PdPb alloy nanocubes (PdPb NCs) by... Read More about Sophisticated construction of binary PdPb alloy nanocubes as robust electrocatalysts toward ethylene glycol and glycerol oxidation..

Coronary vessel supersensitivity to noradrenaline in the presence of chronic sympathetic denervation. (2018)
Journal Article
DRAKE-HOLLAND, A.J. and NOBLE, M.I.M. 2018. Coronary vessel supersensitivity to noradrenaline in the presence of chronic sympathetic denervation. Journal of cardiac disorders and therapy [online], 1(1), article number 103. Available from: http://fulltext.scholarena.co/Coronary-Vessel-Supersensitivity-to-Noradrenaline-in-the-Presence-of-Chronic-Sympathetic-Denervation.php

It is well known that there is usually super-sensitivity to the normal neurotransmitter in chronically denervated organs. The present consensus of opinion is that there is no super-sensitivity of response of myocardial arteriolar resistance vessels t... Read More about Coronary vessel supersensitivity to noradrenaline in the presence of chronic sympathetic denervation..

Has the contribution of selected foods to intakes of energy, fat, saturated fat and sugar changed over time? (2018)
Presentation / Conference
BARTON, K.L., MASSON, L.F., WRIEDEN, W.L., ANDERSON, A.S., SHERRIFF, A. and ARMSTRONG, J.A. 2018. Has the contribution of selected foods to intakes of energy, fat, saturated fat and sugar changed over time? Presented at the 2018 Nutrition Society spring conference: nutrient-nutrient interaction, 26-27 March 2018, Glasgow, UK.

Progress towards the Scottish Dietary goals has been monitored since 2001, principally using Scottish food purchase data collected annually by the Office for National Statistics. Since national and global food supplies are constantly evolving, it is... Read More about Has the contribution of selected foods to intakes of energy, fat, saturated fat and sugar changed over time?.

Parasitized natural killer cells do not facilitate the spread of toxoplasma gondii to the brain. (2018)
Journal Article
PETIT-JENTREAU, L., GLOVER, C. and COOMBES, J.L. 2018. Parasitized natural killer cells do not facilitate the spread of toxoplasma gondiito the brain. Parasite immunology [online], 40(4), article e12522. Available from: https://doi.org/10.1111/pim.12522

Toxoplasmagondii is a protozoan parasite capable of invading immune cells and co-opting their migratory pathways to disseminate through the host. Natural Killer (NK) cells can be directly invaded by the parasite and this invasion alters NK cell migra... Read More about Parasitized natural killer cells do not facilitate the spread of toxoplasma gondii to the brain..

The structures, processes and related outcomes of clinical pharmacy practice as part of the multidisciplinary care of patients with chronic kidney disease: a systematic review. (2018)
Presentation / Conference
AL RAIISI, F., STEWART, D., SALGADO, T., FERNANDEZ-LLIMOS, F., FAHMY, M. and CUNNINGHAM, S. 2018. The structures, processes and related outcomes of clinical pharmacy practice as part of the multidisciplinary care of patients with chronic kidney disease: a systematic review. European journal of hospital pharmacy [online], 25(Supplement 1): proceedings of the 23rd European Association of Hospital Pharmacists (EAHP) congress 2018: hospital pharmacists: show us what you can do!, 21-23 March 2018, Gothenburg, Sweden, article number 4CPS-192. Available from: https://doi.org/10.1136/ejhpharm-2018-eahpconf.282

The aim of this systematic review was to critically appraise, synthesize and present the available evidence for the structures, processes and related outcomes of clinical pharmacy practice in caring from patients with chronic kidney disease. The key... Read More about The structures, processes and related outcomes of clinical pharmacy practice as part of the multidisciplinary care of patients with chronic kidney disease: a systematic review..

Usefulness of hair analysis and psychological tests for identification of alcohol and drugs of abuse consumption in driving license regranting. (2018)
Journal Article
LENDOIRO, E., DE CASTRO, A., JIMENEZ-MORIGOSA, C., GOMEZ-FRAGUELA, X.A., LOPEZ-RIVADULLA, M. and CRUZ, A. 2018. Usefulness of hair analysis and psychological tests for identification of alcohol and drugs of abuse consumption in driving license regranting. Forensic science international [online], 286, pages 239-244. Available from: https://doi.org/10.1016/j.forsciint.2018.03.023

Implementation of the points-based driving license has helped to change driver behavior, and can be linked to to a reduction of traffic accidents and fatalities. In Spain, a driving licence is revoked when all points are lost, and the driver must enr... Read More about Usefulness of hair analysis and psychological tests for identification of alcohol and drugs of abuse consumption in driving license regranting..

A nurse researcher's guide to reflexive interviewing. (2018)
Journal Article
LEAR, H., EBOH, W. and DIACK, L. 2018. A nurse researcher's guide to reflexive interviewing. Nurse researcher [online], 25(4), pages 35-42. Available from: https://doi.org/10.7748/nr.2018.e1550

Background: In a wider doctoral study related to unfavourable experiences of nursing students studying abroad, the researcher undertook a reflexive interview to reduce the potential for bias. Aim: To discuss a method for conducting reflexive intervie... Read More about A nurse researcher's guide to reflexive interviewing..

The impact of pharmacists’ input on the screening, management and prevention of metabolic syndrome. [Protocol] (2018)
Other
AL ADAWI, R., TONNA, A., STEWERT, D., RAYAN, C., ELEDRISI, M., and ABDELAZIZ, H. [2018]. The impact of pharmacists’ input on the screening, management and prevention of metabolic syndrome. [Protocol]. PROSPERO [online], item number CRD42018089862. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42018089862

The aim of this research was to critically appraise, synthesise, and present the available evidence on the impact of pharmacists' input on the screening, prevention and management of metabolic syndrome (MetS). The specific aims were: 1) To determine... Read More about The impact of pharmacists’ input on the screening, management and prevention of metabolic syndrome. [Protocol].

Knowledge and practice characteristics of pharmacists in Qatar towards medication use in pregnancy: a cross-sectional survey. (2018)
Journal Article
ABDUL ROUF, P., THOMAS, B., ELKASSEM, W., TARANNUM, A., AL SAAD, D., GASIM, M.M. and AL HAIL, M. 2018. Knowledge and practice characteristics of pharmacists in Qatar towards medication use in pregnancy: a cross-sectional survey. Eastern Mediterranean health journal [online], 24(2), pages 137-145. Available from: https://doi.org/10.26719/2018.24.2.137

Background: Medication use during pregnancy is common. Pharmacists have an important role in improving medication use during pregnancy. There is a lack of empirical evidence on pharmacists’ knowledge and practice characteristics towards medication us... Read More about Knowledge and practice characteristics of pharmacists in Qatar towards medication use in pregnancy: a cross-sectional survey..

Biotic phase micropollutant distribution in horizontal sub-surface flow constructed wetlands. (2018)
Journal Article
PETRIE, B., ROOD, S., SMITH, B.D., PROCTOR, K., YOUDAN, J., BARDEN, R., KASPRZYK-HORDERN, B. 2018. Biotic phase micropollutant distribution in horizontal sub-surface flow constructed wetlands. Science of the total environment [online], 630, pages 648-657. Available from: https://doi.org/10.1016/j.scitotenv.2018.02.242

The distribution of micropollutants in biotic phases of horizontal sub-surface flow (HSSF) constructed wetlands was investigated. 88 diverse micropollutants (personal care products, pharmaceuticals and illicit drugs) were monitored for in full-scale... Read More about Biotic phase micropollutant distribution in horizontal sub-surface flow constructed wetlands..

Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa. (2018)
Journal Article
O'DRISCOLL, N.H., CUSHNIE, T.P.T., MATTHEWS, K.H. and LAMB, A.J. 2018. Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of escherichia coli and pseudomonas aeruginosa. Archives of microbiology [online], 200(5), pages 793-802. Available from: https://doi.org/10.1007/s00203-018-1485-3

Whilst colistin (polymyxin E) represents the last mainstream treatment option for multi-drug resistant Gram-negative pathogens, details of its mechanism of action remain to be fully resolved. In this study, the effects of sub-inhibitory, inhibitory-b... Read More about Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa..

All Outputs (125)