Outputs (17)

Season, storage and extraction method impact on the phytochemical profile of Terminalia ivorensis. (2023)
Journal Article
MOOMIN, A., RUSSELL, W.R., KNOTT, R.M., SCOBBIE, L., MENSAH, K.B., ADU-GYAMFI, P.K.T. and DUTHIE, S.J. 2023. Season, storage and extraction method impact on the phytochemical profile of Terminalia ivorensis. BMC plant biology [online], 23, article number 162. Available from: https://doi.org/10.1186/s12870-023-04144-8

Terminalia ivorensis (TI) is used in West African ethnomedicine for the treatment of conditions including ulcers, malaria and wounds. Despite its widespread use, the phytochemical profile of TI remains largely undetermined. This research investigated... Read More about Season, storage and extraction method impact on the phytochemical profile of Terminalia ivorensis..

Measuring DNA modifications with the comet assay: a compendium of protocols. (2023)
Journal Article
COLLINS, A., MØLLER, P., GAJSKI, G., DUTHIE, S.J. et al. 2023. Measuring DNA modifications with the comet assay: a compendium of protocols. Nature protocols [online], 18, pages 929-989. Available from: https://doi.org/10.1038/s41596-022-00754-y

The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. The types of damage detected encompass DNA strand breaks and alkali-labile sites (e.g., apurinic/apyrimidinic sites), alkylated an... Read More about Measuring DNA modifications with the comet assay: a compendium of protocols..

Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank. [Dataset] (2023)
Dataset
WANG, L., LI, X., MONTAZERI, A., MACFARLANE, A.J., MOMOLI, F., DUTHIE, S., SENEKAL, M., EGUIAGARAY, I.M., MUNGER, R., BENNETT, D., CAMPBELL, H., RUBINI, M., MCNULTY, H., LITTLE, J. and THEODORATOU, E. 2023. Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank. [Dataset]. American journal of clinical nutrition [online], 117(3), pages 564-575. Available from: https://doi.org/10.1016/j.ajcnut.2023.01.005

The aim of this study was to explore the effects of B vitamins and homocysteine on a wide range of health outcomes based on a large biorepository linking biological samples and electronic medical records. Significant nonlinear dose-response relations... Read More about Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank. [Dataset].

Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank. (2023)
Journal Article
WANG, L., LI, X., MONTAZERI, A., MACFARLANE, A.J., MOMOLI, F., DUTHIE, S., SENEKAL, M., EGUIAGARAY, I.M., MUNGER, R., BENNETT, D., CAMPBELL, H., RUBINI, M., MCNULTY, H., LITTLE, J. and THEODORATOU, E. 2023. Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank. American journal of clinical nutrition [online], 117(3), pages 564-575. Available from: https://doi.org/10.1016/j.ajcnut.2023.01.005

Although a number of health outcomes such as cardiovascular diseases, metabolic-related outcomes, neurological disorders, pregnancy outcomes and cancers have been identified in relation to B vitamins, evidence is of uneven quality and volume, and the... Read More about Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes: analysis of the UK Biobank..

Consumption of a recommended serving of wheat bran cereals significantly increases human faecal butyrate levels in healthy volunteers and reduces markers of inflammation ex vivo. (2021)
Journal Article
NEACSU, M., ANDERSON, S.E., VERSCHOOR, P., VAUGHAN, N.J., HORGAN, G.W., HULSHOF, T., DUNCAN, S.H., DUTHIE, S. and RUSSELL, W.R. 2021. Consumption of a recommended serving of wheat bran cereals significantly increases human faecal butyrate levels in healthy volunteers and reduces markers of inflammation ex vivo. Recent progress in nutrition [online], 1(4), article number 2104002. Available from: https://doi.org/10.21926/rpn.2104002

Wheat bran cereals are an important source of dietary fibre. The aim of the study was to investigate if a high intake (120 g) of fibre rich breakfast cereal (which delivers the UK Government guidelines for fibre intake in one serving but is three-fol... Read More about Consumption of a recommended serving of wheat bran cereals significantly increases human faecal butyrate levels in healthy volunteers and reduces markers of inflammation ex vivo..

Terminalia ivorensis and human health: the impact of Terminalia ivorensis on biomarkers of cyto- and genotoxicity in human cells in vitro. (2021)
Thesis
MOOMIN, A. 2021. Terminalia ivorensis and human health: the impact of Terminalia ivorensis on biomarkers of cyto- and genotoxicity in human cells in vitro. Robert Gordon University, PhD thesis. Hosted on OpenAIR [online]. Available from: https://doi.org/10.48526/rgu-wt-1603185

Terminalia ivorensis (TI) is a tree found in the tropical and sub-tropical zones of the world. It is used in ethnomedicine for the treatment of diuresis, body pains, malaria and wound healing. There are no data investigating the impact of TI on human... Read More about Terminalia ivorensis and human health: the impact of Terminalia ivorensis on biomarkers of cyto- and genotoxicity in human cells in vitro..

The nutritional and cardiovascular health benefits of rapeseed oil-fed farmed salmon in humans are not decreased compared with those of traditionally farmed salmon: a randomized controlled trial. (2020)
Journal Article
DE ROOS, B., WOOD, S., BREMNER, D., BASHIR, S., BETANCOR, M.B., FRASER, W.D., DUTHIE, S.J., HORGAN, G.W. and SNEDDON, A.A. 2021. The nutritional and cardiovascular health benefits of rapeseed oil-fed farmed salmon in humans are not decreased compared with those of traditionally farmed salmon: a randomized controlled trial. European journal of nutrition [online], 60(4), pages 2063-2075. Available from: https://doi.org/10.1007/s00394-020-02396-w

Purpose: Farmed fish are increasingly raised on feeds containing vegetable oils, which affects their composition and possibly health properties. We investigated the effects of consuming farmed salmon, raised on different feeding regimes, on nutrient... Read More about The nutritional and cardiovascular health benefits of rapeseed oil-fed farmed salmon in humans are not decreased compared with those of traditionally farmed salmon: a randomized controlled trial..

Application of the comet assay in human biomonitoring: an hCOMET perspective. (2019)
Journal Article
AZQUETA, A., LADEIRA, C., GIOVANNELLI, L., BOUTET-ROBINET, E., BONASSI, S., NERI, M., GAJSKI, G., DUTHIE, S., DEL BO', C., RISO, P., KOPPEN, G., BASARAN, N., COLLINS, A. and MØLLER, P. 2020. Application of the comet assay in human biomonitoring: an hCOMET perspective. Mutation research/reviews in mutation research [online], 783, article ID 108288. Available from: https://doi.org/10.1016/j.mrrev.2019.108288

The comet assay is a well-accepted biomonitoring tool to examine the effect of dietary, lifestyle, environmental and occupational exposure on levels of DNA damage in human cells. With such a wide range of determinants for DNA damage levels, it become... Read More about Application of the comet assay in human biomonitoring: an hCOMET perspective..

Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes. (2019)
Journal Article
KOLB, A.F., PETRIE, L., MAYER, C.D., PIRIE, L. and DUTHIE, S.J. 2019. Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes. Biochemical journal [online], 476(19), pages 2769-2795. Available from: https://doi.org/10.1042/BCJ20190275

Elevated serum homocysteine, an intermediate of cellular one-carbon metabolism, is an independent risk factor for cardiovascular disease (CVD). Folate deficiency increases serum homocysteine and may contribute to CVD progression. Vascular smooth musc... Read More about Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes..

DNA repair as a human biomonitoring tool: comet assay approaches. (2019)
Journal Article
AZQUETA, A., LANGIE, S.A.S., BOUTET-ROBINET, E., DUTHIE, S., LADEIRA, C, MØLLER, P., COLLINS, A.R. and GODSCHALK, R.W.L. 2019. DNA repair as a human biomonitoring tool: comet assay approaches. Mutation research/reviews in mutation research [online], 781, pages 71-87. Available from: https://doi.org/10.1016/j.mrrev.2019.03.002

The comet assay offers the opportunity to measure both DNA damage and repair. Various comet assay based methods are available to measure DNA repair activity, but some requirements should be met for their effective use in human biomonitoring studies.... Read More about DNA repair as a human biomonitoring tool: comet assay approaches..