Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR.

Rooney, P.H.; Boonsong, A.; McFadyen, M.; McLeod, H.L.; Cassidy, J.; Murray, G.I.

Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR.

Rooney, P.H.; Boonsong, A.; McFadyen, M.; McLeod, H.L.; Cassidy, J.; Murray, G.I.

Authors

P.H. Rooney

A. Boonsong

M. McFadyen

H.L. McLeod

J. Cassidy

G.I. Murray

Abstract

Detection of gene amplification is a process that is recognised as a means of identifying oncogenes. This presentation discusses a study in which the gene copy number of a putative oncogene (ZNF217) was assessed in 80 colon carcinomas by multiplex quantitative real-time PCR. The study found that ZNF217 amplification is a frequent event in colon cancer and that the extent of its amplification can vary greatly between tumours.

Citation

ROONEY, P.H., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. Presented at the 184th Meeting of the Pathological Society of Great Britain and Ireland, 2-5 July 2002, Dublin, Ireland.

Presentation Conference Type	Conference Paper (unpublished)
Conference Name	184th Meeting of the Pathological Society of Great Britain and Ireland
Start Date	Jul 2, 2002
End Date	Jul 5, 2002
Deposit Date	Mar 15, 2023
Publicly Available Date	Mar 15, 2023
Peer Reviewed	Peer Reviewed
Keywords	Gene amplification; Oncogenes; ZNF217; Colon cancer
Public URL	https://rgu-repository.worktribe.com/output/1912265
Additional Information	The extended abstract for this paper has been published with the following citation: ROONEY, P.H., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. Journal of pathology [online], 198(1): synopses of papers from the 184th Meeting of the Pathological Society of Great Britain and Ireland, 2-5 July 2002, Dublin, Ireland, page A33. Available from: https://doi.org/10.1002/path.1711980102 . The extended abstract is also in the book of abstracts (page 64, abstract number 135), which is available on the Internet Archive: https://bit.ly/3ZNA25H