Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR.

Rooney, P.H.; Boonsong, A.; McFadyen, M.; McLeod, H.L.; Cassidy, J.; Murray, G.I.

Abstract

Detection of gene amplification is a process that is recognised as a means of identifying oncogenes. This presentation discusses a study in which the gene copy number of a putative oncogene (ZNF217) was assessed in 80 colon carcinomas by multiplex quantitative real-time PCR. The study found that ZNF217 amplification is a frequent event in colon cancer and that the extent of its amplification can vary greatly between tumours.

Citation

ROONEY, P.H., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. Presented at the 184th Meeting of the Pathological Society of Great Britain and Ireland, 2-5 July 2002, Dublin, Ireland.

• Presentation Conference Type: Conference Paper (unpublished)
• Conference Name: 184th Meeting of the Pathological Society of Great Britain and Ireland
• Conference Location: Dublin, Ireland
• Start Date: Jul 2, 2002
• End Date: Jul 5, 2002
• Deposit Date: Mar 15, 2023
• Publicly Available Date: Mar 15, 2023
• Keywords: Gene amplification; Oncogenes; ZNF217; Colon cancer
• Public URL: https://rgu-repository.worktribe.com/output/1912265
• Additional Information: The extended abstract for this paper has been published with the following citation: ROONEY, P.H., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. Journal of pathology [online], 198(1): synopses of papers from the 184th Meeting of the Pathological Society of Great Britain and Ireland, 2-5 July 2002, Dublin, Ireland, page A33. Available from: https://doi.org/10.1002/path.1711980102 . The extended abstract is also in the book of abstracts (page 64, abstract number 135), which is available on the Internet Archive: https://bit.ly/3ZNA25H