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Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling.

Kelly, D.; King, T.P.; Brown, D.S.; McFadyen, M.


D. Kelly

T.P. King

D.S. Brown

M. McFadyen


Previous studies have suggested that luminal polyamines can directly influence intestinal differentiation of neonatal rats. The present investigation has demonstrated the presence of high levels of polyamines in porcine milk and in the intestinal tissues of suckling pigs. The quantities of polyamines in sow's milk sampled between weeks 1 and 8 of lactation were determined using high performance liquid chromatography (HPLC). The concentration of milk spermidine (SPD) remained constant over the first three to four weeks of lactation but increased four-fold between weeks 4 and 7. Neither putrescine nor spermine (SPN) were detected in any of the milk samples. During intestinal development the mucosal SPD/SPN ratio was elevated between weeks 1 and 3, and weeks 5 and 7. The latter period of increase corresponded with the surge in milk SPD concentration. It is suggested that milk SPD is taken up from the intestinal lumen and is involved in potentiating intestinal differentiation during the latter part of the suckling period.


KELLY, D., KING, T.P., BROWN, D.S. and MCFADYEN, M. 1991. Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling. Reproduction nutrition development [online], 31(1), pages 73-80. Available from:

Journal Article Type Article
Acceptance Date Nov 23, 1990
Online Publication Date Apr 30, 1991
Publication Date Feb 28, 1991
Deposit Date Sep 7, 2020
Publicly Available Date Sep 7, 2020
Journal Reproduction nutrition development
Print ISSN 0926-5287
Electronic ISSN 1297-9708
Publisher EDP Sciences
Peer Reviewed Peer Reviewed
Volume 31
Issue 1
Pages 73-80
Keywords Intestine; Polyamines; Milk; Disaccharidase; Pigs
Public URL


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