Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling.

Kelly, D.; King, T.P.; Brown, D.S.; McFadyen, M.

Abstract

Previous studies have suggested that luminal polyamines can directly influence intestinal differentiation of neonatal rats. The present investigation has demonstrated the presence of high levels of polyamines in porcine milk and in the intestinal tissues of suckling pigs. The quantities of polyamines in sow's milk sampled between weeks 1 and 8 of lactation were determined using high performance liquid chromatography (HPLC). The concentration of milk spermidine (SPD) remained constant over the first three to four weeks of lactation but increased four-fold between weeks 4 and 7. Neither putrescine nor spermine (SPN) were detected in any of the milk samples. During intestinal development the mucosal SPD/SPN ratio was elevated between weeks 1 and 3, and weeks 5 and 7. The latter period of increase corresponded with the surge in milk SPD concentration. It is suggested that milk SPD is taken up from the intestinal lumen and is involved in potentiating intestinal differentiation during the latter part of the suckling period.

Citation

KELLY, D., KING, T.P., BROWN, D.S. and MCFADYEN, M. 1991. Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling. Reproduction nutrition development [online], 31(1), pages 73-80. Available from: https://doi.org/10.1051/rnd:19910107

• Journal Article Type: Article
• Acceptance Date: Nov 23, 1990
• Online Publication Date: Apr 30, 1991
• Publication Date: Feb 28, 1991
• Deposit Date: Sep 7, 2020
• Publicly Available Date: Sep 7, 2020
• Journal: Reproduction nutrition development
• Print ISSN: 0926-5287
• Electronic ISSN: 1297-9708
• Publisher: EDP Sciences
• Peer Reviewed: Peer Reviewed
• Volume: 31
• Issue: 1
• Pages: 73-80
• DOI: https://doi.org/10.1051/rnd%3A19910107
• Keywords: Intestine; Polyamines; Milk; Disaccharidase; Pigs
• Public URL: https://rgu-repository.worktribe.com/output/820160