All Outputs (840)

Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action. (2016)
Journal Article
CUSHNIE, T.P.T., O'DRISCOLL, N.H. and LAMB, A.J. 2016. Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action. Cellular and molecular life sciences [online], 73(23), pages 4471-4492. Available from: https://doi.org/10.1007/s00018-016-2302-2

Efforts to reduce the global burden of bacterial disease and contend with escalating bacterial resistance are spurring innovation in antibacterial drug and biocide development and related technologies such as photodynamic therapy and photochemical di... Read More about Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action..

Synergistic electronic pull of graphene oxide supported Pd nanoparticles on enhancing catalytic activity of electro deposited Pt nanoparticles for methanol oxidation reaction. (2016)
Journal Article
YOUSAF, A.B., KHAN, R., IMRAN, M., FERNANDEZ, C., YUAN, C-Z. and SONG, L. 2016. Synergistic electronic pull of graphene oxide supported Pd nanoparticles on enhancing catalytic activity of electro deposited Pt nanoparticles for methanol oxidation reaction. International journal of electrochemical science [online], 11(8), pages 6735-6746. Available from: https://doi.org/10.20964/2016.08.12

Graphene oxide supported clean Pd nanoparticles were synthesized by using CO as a reducing agent. Pt film was deposited on Pd NPs through electrochemical potential cycling method. The as-developed catalyst, which exhibits higher catalytic performance... Read More about Synergistic electronic pull of graphene oxide supported Pd nanoparticles on enhancing catalytic activity of electro deposited Pt nanoparticles for methanol oxidation reaction..

Enantiomeric profiling of chiral pharmacologically active compounds in the environment with the usage of chiral liquid chromatography coupled with tandem mass spectrometry. (2016)
Journal Article
CAMACHO-MUNOZ, D., PETRIE, B., CASTRIGNANÒ, E. and KASPRZYK-HORDERN, B. 2016. Enantiomeric profiling of chiral pharmacologically active compounds in the environment with the usage of chiral liquid chromatography coupled with tandem mass spectrometry. Current analytical chemistry [online], 12(4), pages 303-314. Available from: https://doi.org/10.2174/1573411012666151009195039

The issue of drug chirality is attracting increasing attention among the scientific community. The phenomenon of chirality has been overlooked in environmental research (environmental occurrence, fate and toxicity) despite the great impact that chira... Read More about Enantiomeric profiling of chiral pharmacologically active compounds in the environment with the usage of chiral liquid chromatography coupled with tandem mass spectrometry..

Effect of deflocculation on the efficiency of sludge reduction by Fenton process. (2016)
Journal Article
AMUDHA, V., KAVITHA, S., FERNANDEZ, C., ADISHKUMAR, S. and RAJESH BANU, J. 2016. Effect of deflocculation on the efficiency of sludge reduction by Fenton process. Environmental science and pollution research [online], 23(19), pages 19281-19291. Available from: https://doi.org/10.1007/s11356-016-7118-y

A novel approach to improve the efficiency of Fenton treatment for sludge reduction through the implication of a deflocculating agent citric acid, for the exclusion of extracellular polymeric substances (EPS) from waste-activated sludge (WAS), was in... Read More about Effect of deflocculation on the efficiency of sludge reduction by Fenton process..

In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut. (2016)
Journal Article
EDMUNDS, J.L., WORGAN, H.J., DOUGAL, K., GIRDWOOD, S.E., DOUGLAS, J.-L. and MCEWAN, N.R. 2016. In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut. Journal of equine science [online], 27(2), pages 49-55. Available from: https://doi.org/10.1294/jes.27.49

The present study uses in vitro analytical techniques to investigate the effect of activated charcoal on the microbial community of the equine hindgut and the metabolites they produce. Incubations were performed in Wheaton bottles using a 50 ml incub... Read More about In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut..

Novel dysprosium and terbium doped taggants for hydrocarbon identification. (2016)
Journal Article
NKWOADA, A.U. and OFFICER, S. 2016. Novel dysprosium and terbium doped taggants for hydrocarbon indentification. Journal of advanced chemical sciences [online], 2(3), pages 296-298. Available from: https://www.jacsdirectory.com/journal-of-advanced-chemical-sciences/articleview.php?id=102

Taggants are synthesized fluorescent materials that have longer lifetime and are able to discriminate against background interference arising from hydrocarbons. Doped taggants were prepared with dysprosium and terbium rare earths in a stable borosili... Read More about Novel dysprosium and terbium doped taggants for hydrocarbon identification..

Synthesis and characterization of high-quality PbI2 nanopowders from depleted SLA accumulator anode and cathode. (2016)
Journal Article
MALEVU, T.D., OCAYA, R.O., TSHABALALA, K.G. and FERNANDEZ, C. 2016. Synthesis and characterization of high-quality PbI2 nanopowders from depleted SLA accumulator anode and cathode. Applied physics A: materials science and processing [online], 122(7), article 630. Available from: https://doi.org/10.1007/s00339-016-0158-9

High-quality lead iodide (PbI2) nanoparticles were synthesized from both anode and cathode of a discarded sealed lead-acid accumulator as starting materials. The structure, morphology, chemical composition and optical properties of washed PbI2 were i... Read More about Synthesis and characterization of high-quality PbI2 nanopowders from depleted SLA accumulator anode and cathode..

Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors. (2016)
Journal Article
LANCE, E., DESPRAT, J., HOLBECH, B.F., GERARD, C., BORMANS, M., LAWTON, L.A., EDWARDS, C. and WIEGAND, C. 2016. Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors. Aquatic toxicology [online], 177, pages 116-124. Available from: https://doi.org/10.1016/j.aquatox.2016.05.024

Freshwater gastropods are increasingly exposed to multiple stressors in the field such as the herbicide glyphosate in Roundup formulations and cyanobacterial blooms either producing or not producing microcystins (MCs), potentially leading to interact... Read More about Accumulation and detoxication responses of the gastropod Lymnaea stagnalis to single and combined exposures to natural (cyanobacteria) and anthropogenic (the herbicide RoundUp® Flash) stressors..

A case study investigation into the use of multi-compartment compliance aids in older people resident in very sheltered housing. (2016)
Journal Article
MACLURE, K., MACLEOD, J., FORBES-MCKAY, K., PAUDYAL, V., CUNNINGHAM, S., STRATH, A., LYNCH, R. and STEWART, D. 2016. A case study investigation into the use of multi-compartment compliance aids in older people resident in very sheltered housing. Patient: patient-centered outcomes research [online] 9(6), pages 583-590. Available from: https://doi.org/10.1007/s40271-016-0178-8

Background: Multi-compartment compliance aids (MCAs) are repackaging systems for solid dosage form medicines, heralded by some as a solution to non-adherence but with little evidence of benefit. Objective: The aim was to use a theoretical approach to... Read More about A case study investigation into the use of multi-compartment compliance aids in older people resident in very sheltered housing..

Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. (2016)
Journal Article
DELGADO-BAQUERIZO, M., GIARAMIDA, L., REICH, P.B., KHACHANE, A.N., HAMONTS, K., EDWARDS, C., LAWTON, L.A. and SINGH, B.K. 2016. Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning. Journal of ecology [online], 104(4), pages 936-946. Available from: https://doi.org/10.1111/1365-2745.12585

1. Biodiversity is declining worldwide with detrimental effects on ecosystems. However, we lack a quantitative understanding of the shape of the relationship between microbial biodiversity and ecosystem function (BEF). This limits our understanding o... Read More about Lack of functional redundancy in the relationship between microbial diversity and ecosystem functioning..

Nutritional and methodological perspectives of zinc ions and complexes: physiological and pathological states. (2016)
Journal Article
MOLINA-LOPEZ, J., PLANELLS DEL POZO, E., FLOREA, D.L., FERNANDEZ, C., OSSO, B.Q., ZALEWSKA, M., KRIZKOVA, S., HEGER, Z., KIZEK, R. and ADAM, V. 2016. Nutritional and methodological perspectives of zinc ions and complexes: physiological and pathological states. International journal of electrochemical science [online], 11(6), pages 4470-4496. Available from: https://doi.org/10.20964/2016.06.38

Zinc, an essential element playing crucial roles in numerous physiological, but also pathological processes, is still one of the most studied elements. The main importance of this metal is especially based on the structural role of zinc ions in many... Read More about Nutritional and methodological perspectives of zinc ions and complexes: physiological and pathological states..

Terminalia ivorensis A. Chev. ethanolic stem bark extract protects against gentamicin-induced renal and hepatic damage in rats. (2016)
Journal Article
ANSAH, C., MOOMIN, A. and BOADU, K.M. 2016. Terminalia ivorensis A. Chev. ethanolic stem bark extract protects against gentamicin-induced renal and hepatic damage in rats. Journal of applied pharmaceutical science [online], 6(4), pages 175-182. Available from: https://doi.org/10.7324/japs.2016.60425

The aim of present study was to investigate the possible protective effects of an ethanolic stem bark extract of Terminalia ivorensis on gentamicin – induced nephrotoxicity and hepatotoxicity in male Sprague-Dawley rats. Groups of animals received ei... Read More about Terminalia ivorensis A. Chev. ethanolic stem bark extract protects against gentamicin-induced renal and hepatic damage in rats..

Exploring behavioural determinants relating to health professional reporting of medication errors: a qualitative study using the theoretical domains framework. (2016)
Journal Article
ALQUBAISI, M., TONNA, A., STRATH, A. and STEWART, D. 2016. Exploring behavioural determinants relating to health professional reporting of medication errors: a qualitative study using the theoretical domains framework. European journal of clinical pharmacology [online], 72(7), pages 887-895. Available from: https://doi.org/10.1007/s00228-016-2054-9

Purpose: Effective and efficient medication reporting processes are essential in promoting patient safety. Few qualitative studies have explored reporting of medication errors by health professionals, and none have made reference to behavioural theor... Read More about Exploring behavioural determinants relating to health professional reporting of medication errors: a qualitative study using the theoretical domains framework..

A modified Delphi study of structures and processes related to medicines management for elderly hospitalised patients in the United Arab Emirates. (2016)
Journal Article
AL SHEMEILI, S., KLEIN, S., STRATH, A., FARES, S. and STEWART, D. 2016. A modified Delphi study of structures and processes related to medicines management for elderly hospitalised patients in the United Arab Emirates. Journal of evaluation in clinical practice [online], 22(5), pages 781-791. Available from: https://doi.org/10.1111/jep.12542

Rationale and aim: The structures and processes around the management of medicines for elderly, hospitalized patients are ill defined. This study aimed to determine consensus related to strategic and operational approaches in the United Arab Emirates... Read More about A modified Delphi study of structures and processes related to medicines management for elderly hospitalised patients in the United Arab Emirates..

Reviewing the literature, how systematic is systematic? (2016)
Journal Article
MACLURE, K., PAUDYAL, V. and STEWART, D. 2016. Reviewing the literature, how systematic is systematic? International journal of clinical pharmacy [online], 38(3), pages 685-694. Available from: https://doi.org/10.1007/s11096-016-0288-3

Introduction Professor Archibald Cochrane, after whom the Cochrane Collaboration is named, was influential in promoting evidence-based clinical practice. He called for 'relevant, valid research' to underpin all aspects of healthcare. Systematic revie... Read More about Reviewing the literature, how systematic is systematic?.

Activity of bisnaphthalimidopropyl derivatives against trypanosoma brucei. (2016)
Journal Article
GRACA, N.A.G., GASPAR, L, COSTA, D.M., LOUREIRO, I., KONG THOO LIN, P., RAMOS, I., ROURA, M., PRUVOST, A., PEMBERTON, I.K., LOUKIL, H., MACDOUGALL, J., TAVARES, J. and CORDEIRO-DA-SILVA, A. 2016. Activity of bisnaphthalimidopropyl derivatives against trypanosoma brucei. Antimicrobial agents and chemotherapy [online], 60(4), pages 2532-2536. Available from: https://doi.org/10.1128/AAC.02490-15

Current treatments for African trypanosomiasis are either toxic, costly, difficult to administer, or prone to elicit resistance. This study evaluated the activity of bisnaphthalimidopropyl (BNIP) derivatives against Trypanosoma brucei. BNIPDiaminobut... Read More about Activity of bisnaphthalimidopropyl derivatives against trypanosoma brucei..

New framework to diagnose the direct disposal of prescribed drugs in wastewater: a case study of the antidepressant fluoxetine. (2016)
Journal Article
PETRIE, B., YOUDAN, J., BARDEN, R., KASPRZYK-HORDERN, B. 2016. New framework to diagnose the direct disposal of prescribed drugs in wastewater: a case study of the antidepressant fluoxetine. Environmental science and technology [online], 50(7), pages 3781-3789. Available from: https://doi.org/10.1021/acs.est.6b00291

Intentional or accidental release (direct disposal) of high loads of unused pharmaceuticals into wastewater can go unnoticed. Here, direct disposal of a pharmaceutical drug via the sewer network was identified for the first time using wastewater anal... Read More about New framework to diagnose the direct disposal of prescribed drugs in wastewater: a case study of the antidepressant fluoxetine..

New insights into the yin and yang of the endocannabinoid system in health and disease. (2016)
Journal Article
WAINWRIGHT, C. 2016. New insights into the yin and yang of the endocannabinoid system in health and disease. British journal of pharmacology [online], 173(7), pages 1113-1115. Available from: https://doi.org/10.1111/bph.13451

This article is part of a themed section on Endocannabionoids, of which the author is guest editor. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v173.7/issuetoc.

A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: soluble bound BMAA found to be an important fraction. (2016)
Journal Article
FAASSEN, E.J., ANTONIOU, M.G., BEEKMAN-LUKASSEN, W., BLAHOVA, L., CHERNOVA, E., CHRISTOPHORIDIS, C., COMBES, A., EDWARDS, C., FASTNER, J., HARMSEN, J., HISKIA, A., ILAG, L.L., KALOUDIS, T., LOPICIC, S., LURLING, M., MAZUR-MARZEC, H., MERILUOTO, J., POROJAN, C., VINER-MOZZINI, Y. and ZGUNA, N. 2016. A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: soluble bound BMAA found to be an important fraction. Marine drugs [online], 14(3), article 45. Available from: https://doi.org/10.3390/md14030045

Exposure to β-Ν-methylamino-l-alanine (BMAA) might be linked to the incidence of amyotrophic lateral sclerosis, Alzheimer's disease and Parkinson's disease. Analytical chemistry plays a crucial role in determining human BMAA exposure and the associat... Read More about A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: soluble bound BMAA found to be an important fraction..

Asking the right question: a comparison of two approaches to gathering data on 'herbals' use in survey based studies. (2016)
Journal Article
MCLAY, J.S., PALLIVALAPPILA, A.R., SHETTY, A., PANDE, B., AL HAIL, M. and STEWART, D. 2016. Asking the right question: a comparison of two approaches to gathering data on 'herbals' use in survey based studies. PLoS ONE [online], 11(2), e0150140. Available from: https://doi.org/10.1371/journal.pone.0150140

Background: Over the last decade academic interest in the prevalence and nature of herbal medicines use by pregnant women has increased significantly. Such data are usually collected by means of an administered questionnaire survey, however a key met... Read More about Asking the right question: a comparison of two approaches to gathering data on 'herbals' use in survey based studies..