Development and characterisation of novel polymer-drug conjugates for the treatment of Alzheimer’s disease

Dr Colin Thompson

Dr Gemma Barron g.barron@rgu.ac.uk
Lecturer

Professor Paul Kong Thoo Lin

A human Glutathione Peroxidase 4 3 untranslated region knock-in mouse model to study susceptibility to colon cancer in obesity Apr 1, 2017 - Dec 31, 2021
Colorectal cancer (CRC) incidence is rising steadily and in parallel with increasing prevalence of obesity in Scotland. Recent data indicate that the highest incidence rates are in the North East. The increasing prevalence of obes... Read More about A human Glutathione Peroxidase 4 3 untranslated region knock-in mouse model to study susceptibility to colon cancer in obesity.

The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2 Jul 1, 2017 - Dec 31, 2019
Medicinal use of natural products, such as, extracts from plants have existed for many years particularly in China and are now widely available around the world. Several different types of cancer including breast cancer are becoming insensitive and r... Read More about The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2.

Protective effects of cannabidiol in doxorubicin induced cardiotoxicity Oct 1, 2018 - Dec 31, 2019

Natural Products from Scottish Non-Food Crops as Multi-Drug Resistance Effectors in Cancer Cells Nov 1, 2020 - Jul 31, 2022
Cultivation of non-food crops for high value chemicals’ production for the pharmaceutical, nutraceutical, food and cosmeceutical industries is a growing area of industrial biotechnology. Plants have been used as a source of traditional medicines and... Read More about Natural Products from Scottish Non-Food Crops as Multi-Drug Resistance Effectors in Cancer Cells.

Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways. Sep 1, 2020 - Dec 31, 2022

The aim of this project is to synthesise a small discrete library of novel compounds based on our lead compound, by applying the methodology developed in our laboratory, and to study the mechanism of action of active one and confirm the multi targe... Read More about Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways..