Development and characterisation of novel polymer-drug conjugates for the treatment of Alzheimer’s disease

Dr Colin Thompson c.thompson@rgu.ac.uk
Principal Lecturer

Dr Gemma Barron g.barron@rgu.ac.uk
Lecturer

Professor Paul Kong Thoo Lin p.v.s.kong-thoo-lin@rgu.ac.uk
Professor

The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2 Jul 1, 2017 - Dec 31, 2019
Medicinal use of natural products, such as, extracts from plants have existed for many years particularly in China and are now widely available around the world. Several different types of cancer including breast cancer are becoming insensitive and r... Read More about The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2.

Natural Products from Scottish Non-Food Crops as Multi-Drug Resistance Effectors in Cancer Cells Nov 1, 2020 - Jul 31, 2022
Cultivation of non-food crops for high value chemicals’ production for the pharmaceutical, nutraceutical, food and cosmeceutical industries is a growing area of industrial biotechnology. Plants have been used as a source of traditional medicines and... Read More about Natural Products from Scottish Non-Food Crops as Multi-Drug Resistance Effectors in Cancer Cells.

Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways. Sep 1, 2020 - Dec 31, 2022

The aim of this project is to synthesise a small discrete library of novel compounds based on our lead compound, by applying the methodology developed in our laboratory, and to study the mechanism of action of active one and confirm the multi... Read More about Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways..

Multitargets drug for Sepsis: Mechanistic studies of drug action through mitigating infection and inflammatory responses associated with sepsis. Oct 1, 2023 - Sep 30, 2025
Sepsis is a life-threatening clinical condition caused by an overreacting immune system fighting an infection. It is often treated with broad-spectrum antibiotics together with anti-inflammatory drugs. However, due to the heterogeneous nature of the... Read More about Multitargets drug for Sepsis: Mechanistic studies of drug action through mitigating infection and inflammatory responses associated with sepsis..