Professor Paul Kong Thoo Lin p.v.s.kong-thoo-lin@rgu.ac.uk
Professor
Professor Paul Kong Thoo Lin p.v.s.kong-thoo-lin@rgu.ac.uk
Professor
Dr Graeme Kay g.kay@rgu.ac.uk
Associate Dean for ESCD
Dr Aakash Welgamage Don a.welgamage-don@rgu.ac.uk
Lecturer
Sepsis is a life-threatening clinical condition caused by an overreacting immune system fighting an infection. It is often treated with broad-spectrum antibiotics together with anti-inflammatory drugs. However, due to the heterogeneous nature of the disease combined with emerging multi-drug resistance in bacteria, the development of an effective treatment has become inherently difficult. We have studied the anticancer, anti-inflammatory, and antibacterial activity of compounds such as vanillin, naphthalimide and phthalimide, demonstrating great potential as medicinal drug precursors. This project aims to study their mechanisms of action and potentially establish the multitarget-directed hypothesis.
Status | Project Live |
---|---|
Funder(s) | Tenovus Scotland |
Value | £12,499.00 |
Project Dates | Oct 1, 2023 - Sep 30, 2025 |
Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways. Sep 1, 2020 - Dec 31, 2022
The aim of this project is to synthesise a small discrete library of novel compounds based on our lead compound, by applying the methodology developed in our laboratory, and to study the mechanism of action of active one and confirm the multi...
Read More about Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways..
Development and characterisation of novel polymer-drug conjugates for the treatment of Alzheimer’s disease Sep 1, 2022 - Aug 31, 2024
Using new polymer-drug compounds to improve the ability to deliver anti-Alzheimer drugs in the body.
About OpenAIR@RGU
Administrator e-mail: publications@rgu.ac.uk
This application uses the following open-source libraries:
Apache License Version 2.0 (http://www.apache.org/licenses/)
Apache License Version 2.0 (http://www.apache.org/licenses/)
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
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