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Multi-residue analysis of 90 emerging contaminants in liquid and solid environmental matrices by ultra-high-performance liquid chromatography tandem mass spectrometry.

Petrie, Bruce; Youdan, Jane; Barden, Ruth; Kasprzyk-Hordern, Barbara

Authors

Jane Youdan

Ruth Barden

Barbara Kasprzyk-Hordern



Abstract

Reported here in is new analytical methodology for the determination of 90 emerging contaminants (ECs)in liquid environmental matrices (crude wastewater, final effluent and river water). The application of a novel buffer, ammonium fluoride improved signal response for several ECs determined in negative ionisation mode. Most notably the sensitivity of steroid estrogens was improved by 4–5 times in environmental extracts. Method recoveries ranged from 40 to 152% in all matrices and method quantitation limits (MQLs) achieved were [less than]1 ng L−1for numerous ECs. Development of a microwave assisted extraction(MAE) protocol as an additional sample extraction step for solid matrices enabled 63 ECs to be simultaneously analysed in digested sludge. To the authors knowledge this is considerably more than any previously reported MAE method. Here, MQLs ranged from 0.1–24.1 ng g−1dry weight. The application of MAE offers several advantages over pressurized liquid extraction including faster sample preparation, lower solvent requirements, and the ability to perform several extractions simultaneously as well as lower purchasing and running costs. To demonstrate the method’s sensitivity, application to environmental samples revealed 68 and 40 ECs to be above their respective MQL in liquid environmental samples and digested sludge, respectively. To date, this is the most comprehensive multi-residue analytical method reported in the literature for the determination of ECs in both liquid and solid environmental matrices.

Citation

PETRIE, B., YOUDAN, J., BARDEN, R. and KASPRZYK-HORDERN, B. 2016. Multi-residue analysis of 90 emerging contaminants in liquid and solid environmental matrices by ultra-high-performance liquid chromatography tandem mass spectrometry. Journal of chromatography A [online], 1431, pages 64-78. Available from: https://doi.org/10.1016/j.chroma.2015.12.036

Journal Article Type Article
Acceptance Date Dec 12, 2015
Online Publication Date Dec 17, 2015
Publication Date Jan 29, 2016
Deposit Date Apr 13, 2021
Publicly Available Date Apr 13, 2021
Journal Journal of Chromatography A
Print ISSN 0021-9673
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 1431
Pages 64-78
DOI https://doi.org/10.1016/j.chroma.2015.12.036
Keywords Pharmaceutical; Illicit drug; Wastewater; Liquid chromatography; Sludge; Mass spectrometry; Microwave assisted extraction
Public URL https://rgu-repository.worktribe.com/output/1269175
Related Public URLs https://rgu-repository.worktribe.com/output/1308245

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