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Menstrual cycle variations in oestradiol and progesterone have no impact on in vivo medial gastrocnemius tendon mechanical properties.

Burgess, K.E.; Pearson, S.J.; Onambélé, G.L.

Authors

S.J. Pearson

G.L. Onambélé



Abstract

Tendon tissue contains oestrogen receptors and is therefore likely to be responsive to female sex hormones. Here we examine any effect of levels of female sex hormones associated with the menstrual cycle phase on corresponding tendon mechanical properties. Fifteen healthy females aged 23 (SEM 1.0 years) underwent three assessments of medial gastrocnemius tendon mechanical properties. Assessments were carried out once during days 1-4, 12-14 and 20-23 (with day 1 being the first day of menstruation). Venous blood samples were taken on the same days as tendon properties assessments to quantify serum levels of oestradiol and progesterone. There was no significant difference in the stiffness of the medial gastrocnemius tendon over the course of the menstrual cycle (days 1-4, 65.08 (SEM 5.16 Nm m-1), days 12-14, 62.73 (SEM 5.82 Nm m-1), days 20-23, 66.74 (SEM 7.14 Nm m-1)). There were also no significant differences in tendon length and cross-sectional area which led to no significant differences in Young's modulus values. No correlations were found between serum levels of oestradiol and/or progesterone and tendon stiffness and/or Young's modulus. Acute fluctuations in female sex hormones have no significant effect on medial gastrocnemius tendon mechanical properties. In a context where studies are often limited to selecting only oral contraceptive-users as participants in order to minimise potential noise related to the anticipated effects of menstrual cycle hormones on physical performance, our findings provide the basis for enabling the pooling of female tendon data, regardless of the phase of the menstrual cycle of individual participant.

Citation

BURGESS, K.E., PEARSON, S.J. and ONAMBÉLÉ, G.L. 2009. Menstrual cycle variations in oestradiol and progesterone have no impact on in vivo medial gastrocnemius tendon mechanical properties. Clinical biomechanics [online], 24(6), pages 504-509. Available from: https://doi.org/10.1016/j.clinbiomech.2009.03.011

Journal Article Type Article
Acceptance Date Mar 25, 2009
Online Publication Date Apr 23, 2009
Publication Date Jul 31, 2009
Deposit Date Sep 4, 2023
Publicly Available Date Jan 16, 2024
Journal Clinical biomechanics
Print ISSN 0268-0033
Electronic ISSN 1879-1271
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 24
Issue 6
Pages 504-509
DOI https://doi.org/10.1016/j.clinbiomech.2009.03.011
Keywords Collagen; Female; Sex hormones; Structural properties
Public URL https://rgu-repository.worktribe.com/output/2060316

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