All Outputs (1205)

The role of selenium supplementation in cardiovascular disease prevention: an in vitro study to identify the molecular mechanism(s). (2015)
Presentation / Conference
LEIGHTON, D., GOUA, M., DOLAN, E., BURGESS, K. and BERMANO, G. 2015. The role of selenium supplementation in cardiovascular disease prevention: an in vitro study to identify the molecular mechanism(s). Presented at the 2015 Nutrition Society Scottish section meeting: diet, gene regulation and metabolic disease, 25-26 March 2015, Aberdeen, UK.

Obesity is a worldwide epidemic, with two thirds of the UK population either overweight or obese (body mass index (BMI) 25–29·9 and >30 kg/m2 respectively). Obesity is characterised by systemic oxidative stress (OS), which itself results from chronic... Read More about The role of selenium supplementation in cardiovascular disease prevention: an in vitro study to identify the molecular mechanism(s)..

Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. (2015)
Journal Article
IBIE, C.O., THOMPSON, C.J. and KNOTT, R. 2015. Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. Colloid and polymer science [online], 293(6), pages 1737-1748. Available from: https://doi.org/10.1007/s00396-015-3561-4

Polyallylamine (Paa) was quaternised by methylation of its primary amines using methyl iodide to yield quaternised Paa (QPaa). Average level of polymer quaternisation was determined by elemental analysis and was found to be 72 ± 2mol%. Subsequent thi... Read More about Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine..

Now it's over to you: a workbook approach. (2015)
Book Chapter
MCFADYEN, M.C.E. 2015. Now it's over to you: a workbook approach. In Thomas, L. (ed.) Compendium of effective practice in directed independent learning. York: Higher Education Academy [online], pages 85-87. Available from: https://www.advance-he.ac.uk/knowledge-hub/compendium-effective-practice-directed-independent-learning

During the oncology topic within the third year 'Clinical Pharmacology and Therapeutics 2' module (CPT2) of the MPharm at Robert Gordon University (RGU), it quickly became apparent that students had difficulty in placing complex concepts into context... Read More about Now it's over to you: a workbook approach..

An exploratory study of the views of community pharmacy staff on the management of patients with undiagnosed skin problems. (2015)
Journal Article
TUCKER, R. and STEWART, D. 2015. An exploratory study of the views of community pharmacy staff on the management of patients with undiagnosed skin problems. International journal of pharmacy practice [online], 23(6), pages 390-398. Available from: https://doi.org/10.1111/IJPP.12179

Objective: The aim of this study was to explore pharmacist and medicine counter assistant (MCA) perceptions of community pharmacy management of patients presenting with symptomatic skin problems. Methods: The study involved semi-structured telephone... Read More about An exploratory study of the views of community pharmacy staff on the management of patients with undiagnosed skin problems..

Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands and Western Isles. (2015)
Journal Article
RUSHWORTH, G.F., DIACK, L., MACROBBIE, A., MUNOZ, S.-A., PFLEGER, S., STEWART, D. 2015. Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands and Western Isles. Public health [online], 129(3), pages 244-251. Available from: https://doi.org/10.1016/j.puhe.2015.01.005

Objectives: Sparsely populated areas are potentially predisposed to health inequalities due to limited access to services. This study aimed to explore and describe issues of access to medicines and related advice experienced by residents of the Scott... Read More about Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands and Western Isles..

A study on temporal trends and estimates of fate of Bisphenol A in agricultural soils after sewage sludge amendment. (2015)
Journal Article
ZHANG, Z., LE VELLY, M., RHIND, S.M., KYLE, C.E., HOUGH, R.L., DUFF, E.I. and MCKENZIE, C. 2015. A study on temporal trends and estimates of fate of Bisphenol A in agricultural soils after sewage sludge amendment. Science of the total environment [online], 515-516, pages 1-11. Available from: https://doi.org/10.1016/j.scitotenv.2015.01.053

Temporal concentration trends of BPA in soils were investigated following sewage sludge application to pasture (study 1: short term sludge application; study 2: long term multiple applications over 13years). The background levels of BPA in control so... Read More about A study on temporal trends and estimates of fate of Bisphenol A in agricultural soils after sewage sludge amendment..

Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana. (2015)
Journal Article
AMPONSAH, A.O., VOSPER, H. and MARFO, A.F.A., 2015. Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana. Malaria research and treatment [online], 2015, Article ID 452539. Available from: https://doi.org/10.1155/2015/452539

Our aim was to measure the adherence to Artemisinin based Combination Therapy and to determine patient related factors that affect adherence. Three hundred (300) patients receiving ACT treatment dispensed from the community pharmacy were randomly sel... Read More about Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana..

Deferiprone, a non-toxic reagent for determination of iron in samples via sequential injection analysis. (2015)
Journal Article
PRAGOURPUN, K., SAKEE, U., FERNANDEZ, C. and KRUANETR, S. 2015. Deferiprone, a non-toxic reagent for determination of iron in samples via sequential injection analysis. Spectrochimica acta, part A: molecular and biomolecular spectroscopy [online], 142, pages 110-117. Available from: https://doi.org/10.1016/j.saa.2015.01.081

We present for the first time the use of deferiprone as a non-toxic complexing agent for the determination of iron by sequential injection analysis in pharmaceuticals and food samples. The method was based on the reaction of Fe(III) and deferiprone i... Read More about Deferiprone, a non-toxic reagent for determination of iron in samples via sequential injection analysis..

Conductance studies of aqueous ionic liquids solutions [emim][BF4] and [bmim][BF4] at temperatures from (283.15 to 318.15) K. (2015)
Journal Article
BORUŃ, A., FERNANDEZ, C. and BALD, A. 2015. Conductance studies of aqueous ionic liquids solutions [emim][BF4] and [bmim][BF4] at temperatures from 283.15 to 318.15 K. International journal of electrochemical science [online], 10(3), pages 2120-2129. Available from: https://doi.org/10.1016/S1452-3981(23)04834-4

We present for the first time the determination of molar conductances, Lambda, of ionic liquids solutions (ILs) such as 1-ethyl-3-methylimidazolium tetrafluoroborate [emim][BF4] and 1-butyl-3-methylimidazolium tetrafluoroborate [bmim][BF4] as a funct... Read More about Conductance studies of aqueous ionic liquids solutions [emim][BF4] and [bmim][BF4] at temperatures from (283.15 to 318.15) K..

Interagency adult support and protection practice of police and health and social care professionals: a realistic evaluation approach. (2015)
Report
JOSEPH, S., DIACK, L., HEYMAN, I., KLEIN, S., MCCLUSKEY, S., WOOLNOUGH, P., FALCONER, M., REDDISH, A. and MACLEAN, E. 2015. Interagency adult support and protection practice of police and health and social care professionals: a realistic evaluation approach. SIPR research summary number 19. Dundee: Scottish Institute for Policing Research, School of Social Sciences, University of Dundee [online]. Available from: http://www.sipr.ac.uk/Plugin/Publications/assets/files/Research_Summary_19.pdf

The purpose of this project was to investigate the interagency Adult Support and Protection practices of police, health and social care professionals in Scotland by means of a Realistic Evaluation Approach. The study comprised of two specific phases.... Read More about Interagency adult support and protection practice of police and health and social care professionals: a realistic evaluation approach..

Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. (2014)
Journal Article
BARRON, G.A., BORDET, E., GOUA, M. and BERMANO. G. 2014. Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. Current angiogenesis [online], 3(3), pages 152-163. Available from: https://doi.org/10.2174/2211552803666141113211829

Increased levels of inflammatory markers such as tumour necrosis factor-α (TNFα) and interleukin- 6 (IL-6) have been associated with formation of new blood vessels, or angiogenesis, and linked to chronic inflammation in obesity. This study aimed to e... Read More about Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system..

In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. (2014)
Journal Article
IBIE, C., KNOTT, R. and THOMPSON, C.J. 2015. In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. International journal of pharmaceutics [online], 479(1), pages 103-117. Available from: https://doi.org/10.1016/j.ijpharm.2014.12.058

The biocompatibility and cellular uptake of polymer, insulin polyelectrolyte complexes (PECs) prepared using polyallylamine-based polymers was evaluated in-vitro using Caco-2 cell monolayers as a predictive model for human small intestinal epithelial... Read More about In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells..

A mixed methods investigation into the use of non-technical skills by community and hospital pharmacists. (2014)
Journal Article
IRWIN, A. and WEIDMANN, A. 2015. A mixed methods investigation into the use of non-technical skills by community and hospital pharmacists. Research in social and administrative pharmacy [online], 11(5), pages 675-685. Available from: https://doi.org/10.1016/j.sapharm.2014.11.006

Background: Non-technical skills refer to the social and cognitive factors that may influence efficient and safe job performance. Non-technical skills are an important element of patient safety in a variety of health care disciplines, including surge... Read More about A mixed methods investigation into the use of non-technical skills by community and hospital pharmacists..

The electrochemical and statistical evaluation of isolation of mellitin and apamin from honey bee (Apis Mellifera) venom. (2014)
Journal Article
NGUYEN, H. V., HEGER, Z., KOMINKOVA, M., MICHALEK, P., GUMULEC, J., GURAN, R., PRIDAL, A., FERNANDEZ, C., HYNEK, D., ADAM, V. and KIZEK, R. 2015. The electrochemical and statistical evaluation of isolation of mellitin and apamin from honey bee (Apis Mellifera) venom. International journal of electrochemical science [online] , 10(2), pages 1249-1260. Available from: https://doi.org/10.1016/S1452-3981(23)05069-1

We present in this manuscript for the first time the electrochemical and statistical evaluation of FPLC isolation of mellitin and apamin from honey bee (Apis mellifera) venom. Venoms are extremely complex blends of diverse substances that target a my... Read More about The electrochemical and statistical evaluation of isolation of mellitin and apamin from honey bee (Apis Mellifera) venom..

Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice. (2014)
Journal Article
DUTHIE, S.J., BEATTIE, J.H., GORDON, M.-J., PIRIE, L.P., NICOL, F., REID, M.D., DUNCAN, G.J., CANTLAY, L., HORGAN, G. and MCNEIL, C.J. 2015. Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice. Genes and nutrition [online], 10(1), article 446. Available from: https://doi.org/10.1007/s12263-014-0446-y

Low B vitamin status is linked with human vascular disease. We employed a proteomic and biochemical approach to determine whether nutritional folate deficiency and/or hyperhomocysteinemia altered metabolic processes linked with atherosclerosis in Apo... Read More about Nutritional B vitamin deficiency alters the expression of key proteins associated with vascular smooth muscle cell proliferation and migration in the aorta of atherosclerotic apolipoprotein E null mice..

Kinetic and kinematic changes during a 30-repetition bout of the barbell clean. (2014)
Journal Article
SWINTON, P.A., SHITANSHI, D., DOLAN, E., BURGESS, K., SINGH, B. and ASPE, R. 2016. Kinetic and kinematic changes during a 30-repetition bout of the barbell clean. Journal of athletic enhancement [online], 5(1). Available from: https://doi.org/10.4172/2324-9080.1000220

The purpose of this stduy was to investigate the biomechanical effects of performing a large number of repetitions with a technically demanding exercise, as is recommended in many extreme conditioning programs. Sixteen trained male participants (age:... Read More about Kinetic and kinematic changes during a 30-repetition bout of the barbell clean..

General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer. (2014)
Journal Article
RUSHWORTH, G.F., DIACK, L., RUDD, I.G. and STEWART, D. 2015. General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer. International journal of clinical pharmacy [online], 37(1), pages 4-7. Available from: https://doi.org/10.1007/s11096-014-0033-8

Background The potential of warfarin related harm is increased if clinicians lack the full patient specific information to make informed decisions—an e-proforma has been developed to communicate this information on hospital discharge. Objective To de... Read More about General practitioner views of an electronic high-risk medicine proforma to facilitate information transfer..

Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. (2014)
Thesis
MCGEE, D. 2014. Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens. Robert Gordon University, MRes thesis.

The marine amphipod Corophium volutator is an important source of food for many fish and wading birds, making it an important species in an estuarine environment and a relevant toxicological test species. Historical data has indicated that seasonal v... Read More about Overcoming the seasonal variations in fitness of the amphipod Corophium Volutator as an environmental toxicology test species using laboratory cultured specimens..

Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria. (2014)
Journal Article
MINAS, K., KARUNAKARAN, E., BOND, T., GANDY, C., HONSBEIN, A., MADSEN, M., AMEZAGA, J., AMTMANN, A., TEMPLETON, M.R., BIGGS, C.A. and LAWTON, L. 2015. Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria. Desalination and water treatment [online], 55(10): selected papers presented at 2015 Desalination for the environment conference: clean water and energy, 11-15 May 2014, Limassol, Cyprus, pages 2647-2668. Available from: https://doi.org/10.1080/19443994.2014.940647

Although desalination by membrane processes is a possible solution to the problem of freshwater supply, related cost and energy demands prohibit its use on a global scale. Hence, there is an emerging necessity for alternative, energy and cost-efficie... Read More about Biodesalination: an emerging technology for targeted removal of Na+ and Cl− from seawater by cyanobacteria..

GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses. (2014)
Journal Article
WALSH, S.K., HECTOR, E.E., ANDREASSON, A.-C., JONSSON-RYLANDER, A.-C. and WAINWRIGHT, C. L. 2014. GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses. PLoS ONE [online], 9(10), article number e108999. Available from: https://doi.org/10.1371/journal.pone.0108999

G protein coupled receptor 55 (GPR55) is expressed throughout the body and, although its exact physiological function is unknown, studies have suggested that it has a role in the cardiovascular system. In particular, GPR55 has been proposed as mediat... Read More about GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses..