All Outputs (857)

Inheritance patterns of coat colouration and horn number in Jacob sheep. (2018)
Journal Article
ANJOLA, O.A. and MCEWAN, N.R. 2018. Inheritance patterns of coat colouration and horn number in Jacob sheep. Open Agriculture [online], 3(1), pages 363-367. Available from: https://doi.org/10.1515/opag-2018-0040

The allele for black coat colour is dominant relative to the allele for lilac in Jacob sheep and is affected by a single gene locus. The percentage of this colouration, as opposed to white fleece, across the body has a heritability value of 0.255. Th... Read More about Inheritance patterns of coat colouration and horn number in Jacob sheep..

Perspectives of healthcare professionals in Qatar on causes of medication errors: a mixed methods study of safety culture. (2018)
Journal Article
STEWART, D., THOMAS, B., MACLURE, K., PALLIVALAPILA, A., EL KASSEM, W., AWAISU, A., MCLAY, J.S., WILBUR, K., WILBY, K., RYAN, C., DIJKSTRA, A., SINGH, R. and AL HAIL, M. 2018. Perspectives of healthcare professionals in Qatar on causes of medication errors: a mixed methods study of safety culture. PLoS one [online], 13(9), article ID e0204801. Available from: https://doi.org/10.1371/journal.pone.0204801

Background: There is a lack of robust, rigorous mixed methods studies of patient safety culture generally and notably those which incorporate behavioural theories of change. The study aimed to quantify and explain key aspects of patient safety cultur... Read More about Perspectives of healthcare professionals in Qatar on causes of medication errors: a mixed methods study of safety culture..

Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present and future. (2018)
Journal Article
HUWS, S.A., CREEVEY, C.J., OYAMA, L.B., MIZRAHI, I., DENMAN, S.E., POPOVA, M., MUÑOZ-TAMAYO, R., FORANO, E., WATERS, S.M., HESS, M., TAPIO, I., SMIDT, H., KRIZSAN, S.J., YÁÑEZ-RUIZ, D.R., BELANCHE, A., GUAN, L., GRUNINGER. R.J., MCALLISTER, T.A., NEWBOLD, C.J., ROEHE. R., DEWHURST, R.J., SNELLING, T.J., WATSON, M., SUEN, G., HART, E.H., KINGSTON-SMITH, A.H., SCOLLAN, N.D., DO PRADO, R.M., PILAU, E.J., MANTOVANI, H.C., ATTWOOD, G.T., EDWARDS, J.E., MCEWAN, N.R., MORRISSON, S., MAYORGA, O.L., ELLIOTT, C. and MORGAVI, D.P. 2018. Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present and future. Frontiers in microbiology [online], 9, Article 2161. Available from: https://doi.org/10.3389/fmicb.2018.02161

The rumen is a complex ecosystem composed of anaerobic bacteria, protozoa, fungi, methanogenic archaea and phages. These microbes interact closely to breakdown plant material that cannot be digested by humans, whilst providing metabolic energy to the... Read More about Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present and future..

Complexation of novel thiomers and insulin to protect against in vitro enzymatic degradation: towards oral insulin delivery. (2018)
Journal Article
IBIE, C.O., KNOTT, R.M. and THOMPSON, C.J. 2019. Complexation of novel thiomers and insulin to protect against in vitro enzymatic degradation: towards oral insulin delivery. Drug development and industrial pharmacy [online], 45(1), pages 67-75. Available from: https://doi.org/10.1080/03639045.2018.1517776

A significant barrier to oral insulin delivery is its enzymatic degradation in the gut. Nano-sized polymer-insulin polyelectrolyte complexes (PECS) have been developed to protect insulin against enzymatic degradation. Poly(allylamine) (Paa) was trime... Read More about Complexation of novel thiomers and insulin to protect against in vitro enzymatic degradation: towards oral insulin delivery..

A novel PAA derivative with enhanced drug efficacy in pancreatic cancer cell lines. (2018)
Journal Article
ALSURAIFI, A., KONG THOO LIN, P., CURTIS, A., LAMPROU, D.A. and HOSKINS, C. 2018. A novel PAA derivative with enhanced drug efficacy in pancreatic cancer cell lines. Pharmaceuticals [online], 11(4), article ID 91. Available from: https://doi.org/10.3390/ph11040091

Nanoparticles have been shown to be effective drug carriers in cancer therapy. Pancreatic cancer forms dense tumours which are often resistant to drug molecules. In order to overcome such multidrug resistance, new drug entities, novel delivery system... Read More about A novel PAA derivative with enhanced drug efficacy in pancreatic cancer cell lines..

Trigonelline prevents high cholesterol and high fat diet induced hepatic lipid accumulation and lipo-toxicity in C57BL/6J mice, via restoration of hepatic autophagy. (2018)
Journal Article
SHARMA, L., LONE, N.A., KNOTT, R.M., HASSAN, A., ABDULLAH, T. 2018. Trigonelline prevents high cholesterol and high fat diet induced hepatic lipid accumulation and lipo-toxicity in C57BL/6J mice, via restoration of hepatic autophagy. Food and chemical toxicology [online], 121, pages 283-296. Available from: https://doi.org/10.1016/j.fct.2018.09.011

Non-alcoholic fatty liver disease (NAFLD) is often linked with impaired hepatic autophagy. Here, we studied the alterations in hepatocellular autophagy by high cholesterol and high-fat diet (HC-HF) diet in C57BL/6J mice, and by palmitic acid (PA), in... Read More about Trigonelline prevents high cholesterol and high fat diet induced hepatic lipid accumulation and lipo-toxicity in C57BL/6J mice, via restoration of hepatic autophagy..

Preparation of 3D spherical Ni/Al LDHs with significantly enhanced electrochemical performance as a superior cathode material for Ni/MH batteries. (2018)
Journal Article
NIE, Y., LI, W., PAN, J., SENTHIL, R.A., FERNANDEZ, C., KHAN, A., SUN, Y. and LIU, J. 2018. Preparation of 3D spherical Ni/Al LDHs with significantly enhanced electrochemical performance as a superior cathode material for Ni/MH batteries. Electrochimica acta [online], 289, pages 333-341. Available from: https://doi.org/10.1016/j.electacta.2018.09.043

Nickel-based hydroxides with excellent electrochemical performance have been considered as cathode materials for Ni/MH batteries. In this paper, a Ni/Al layered double hydroxides (Ni/Al LDHs) material with three-dimensional (3D) spherical structure i... Read More about Preparation of 3D spherical Ni/Al LDHs with significantly enhanced electrochemical performance as a superior cathode material for Ni/MH batteries..

Detecting genetic regions associated with height in the native ponies of the British Isles by using high density SNP genotyping. (2018)
Journal Article
SKUJINA, I., WINTON, C.L., HEGARTY, M.J., MCMAHON, R., NASH, D.M., DAVIES-MOREL, M.C.G. and MCEWAN, N.R. 2018. Detecting genetic regions associated with height in the native ponies of the British Isles by using high density SNP genotyping. Genome [online], 61(10), pages 767-770. Available from: https://doi.org/10.1139/gen-2018-0006

Height is an important characteristic in the equine industry, although little is known about its genetic control in native British breeds of ponies. This study aimed to map QTL data with the withers height in four pony breeds native to the British Is... Read More about Detecting genetic regions associated with height in the native ponies of the British Isles by using high density SNP genotyping..

Folate, genomic stability and colon cancer: the use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring. (2018)
Journal Article
CATALA, G.N., BESTWICK, C.S., RUSSELL, W.R., TORTORA, K., GIOVANNELLI, L., MOYER, M.P., LENDOIRO, E. and DUTHIE, S.J. 2019. Folate, genomic stability and colon cancer: the use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring. Mutation research: genetic toxicology and environmental mutagenesis [online], 843, pages 73-80. Available from: https://doi.org/10.1016/j.mrgentox.2018.08.012

Intake of folate (vitamin B9) is strongly inversely linked with human cancer risk, particularly colon cancer. In general, people with the highest dietary intake of folate or with high blood folate levels are at a reduced risk (approx. 25%) of develop... Read More about Folate, genomic stability and colon cancer: the use of single cell gel electrophoresis in assessing the impact of folate in vitro, in vivo and in human biomonitoring..

Assessment of bisphenol-A in the urban water cycle. (2018)
Journal Article
PETRIE, B., LOPARDO, L., PROCTOR, K., YOUDAN, J., BARDEN, R. and KASPRZYK-HORDERN, B. 2019. Assessment of bisphenol-A in the urban water cycle. Science of the total environment [online], 650(1), pages 900-907. Available from: https://doi.org/10.1016/j.scitotenv.2018.09.011

The plasticizer bisphenol-A (BPA) is common to municipal wastewaters and can exert toxicity to exposed organisms in the environment. Here BPA concentration at 5 sewage treatment works (STW) and distribution throughout a river catchment in South West... Read More about Assessment of bisphenol-A in the urban water cycle..

Pharmacist services for non-hospitalised patients. (2018)
Journal Article
DE BARRA, M., SCOTT, C.L., SCOTT, N.W., JOHNSTON, M., DE BRUIN, M., NKANSAH, N., BOND, C.M., MATHESON, C.I., RACKOW, P., WILLIAMS, A.J. and WATSON, M.C. 2018. Pharmacist services for non-hospitalised patients. Cochrane database of systematic reviews [online], Issue 9, Article CD013102. Available from: https://doi.org/10.1002/14651858.CD013102

Background: This review focuses on non-dispensing services from pharmacists, i.e. pharmacists in community, primary or ambulatory-care settings, to non-hospitalised patients, and is an update of a previously-published Cochrane Review. Objectives: To... Read More about Pharmacist services for non-hospitalised patients..

Austrian pharmacy students' views, experiences and attitudes on an elective clinical pharmacy teaching event delivered in the English language. (2018)
Journal Article
WEIDMANN, A.E., DONAT, I. and ORTNER, A. 2018. Austrian pharmacy students' views, experiences and attitudes on an elective clinical pharmacy teaching event delivered in the English language. Pharmacy education [online], 18(1), pages 224-230. Available from: http://pharmacyeducation.fip.org/pharmacyeducation/article/view/532/574

Introduction: The World Health Organisation (WHO) and the International Pharmaceutical Federation (FIP) recommend emphasising clinical education within a balanced pharmacy curriculum. During the summer of 2016 the University of Graz (KFU), sponsored... Read More about Austrian pharmacy students' views, experiences and attitudes on an elective clinical pharmacy teaching event delivered in the English language..

Carbon nanomaterials for targeted cancer therapy drugs: a critical review. (2018)
Journal Article
HOSNEDLOVA, B., KEPINSKA, M., FERNANDEZ, C., PENG, Q., RUTTKAY-NEDECKY, B., MILNEROWICZ, H. and KIZEK, R. 2019. Carbon nanomaterials for targeted cancer therapy drugs: a critical review. Chemical record [online], 19(2-3), pages 502-522. Available from: https://doi.org/10.1002/tcr.201800038

Cancer represents one of the main causes of human death in developed countries. Most current therapies, unfortunately, carry a number of side effects, such as toxicity and damage to healthy cells, as well as the risk of resistance and recurrence. The... Read More about Carbon nanomaterials for targeted cancer therapy drugs: a critical review..

GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues. (2018)
Journal Article
LIPINA, C., WALSH, S.K., MITCHELL, S.E., SPEAKMAN, J.R., WAINWRIGHT, C.L. and HUNDAL, H.S. 2019. GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues. FASEB journal [online], 33(1), pages 1299-1312. Available from: https://doi.org/10.1096/fj.201800171R

Emerging evidence indicates that G-protein coupled receptor 55 (GPR55), a nonclassic receptor of the endocannabinoid system that is activated by L-α-lysophosphatidylinositol and various cannabinoid ligands, may regulate endocrine function and energy... Read More about GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues..

Analysis of the composition of milk in the first three lactations in Ayrshire cattle across four decades. (2018)
Journal Article
KNIGHT, R.B. and MCEWAN, N.R. 2018. Analysis of the composition of milk in the first three lactations in Ayrshire cattle across four decades. Open agriculture [online], 3(1), pages 245-249. Available from: https://doi.org/10.1515/opag-2018-0026

Using historic lactation records for Ayrshire cattle, we report a gradual increase in the production of milk, butter fat and protein levels across four decades. This was generally at the extent of attaining a level of increase per decade which was si... Read More about Analysis of the composition of milk in the first three lactations in Ayrshire cattle across four decades..

Ruthenium oxide-carbon-based nanofiller-reinforced conducting polymer nanocomposites and their supercapacitor applications. (2018)
Journal Article
ATES, M. and FERNANDEZ, C. 2019. Ruthenium oxide-carbon-based nanofiller-reinforced conducting polymer nanocomposites and their supercapacitor applications. Polymer bulletin [online], 76(5), pages 2601-2619. Available from: https://doi.org/10.1007/s00289-018-2492-x

In this review article, we have presented for the first time the new applications of supercapacitor technologies and working principles of the family of RuO2-carbon-based nanofiller-reinforced conducting polymer nanocomposites. Our review focuses on... Read More about Ruthenium oxide-carbon-based nanofiller-reinforced conducting polymer nanocomposites and their supercapacitor applications..

Multi-residue analysis of chiral and achiral trace organic contaminants in soil by accelerated solvent extraction and enantioselective liquid chromatography tandem-mass spectrometry. (2018)
Journal Article
PETRIE, B., MRAZOVA, J., KASPRZYK-HORDERN, B. and YATES, K. 2018. Multi-residue analysis of chiral and achiral trace organic contaminants in soil by accelerated solvent extraction and enantioselective liquid chromatography tandem-mass spectrometry. Journal of chromatography A [online], 1572, pages 62-71. Available from: https://doi.org/10.1016/j.chroma.2018.08.034

Reported here is the first analytical methodology for the enantiomeric determination of chiral trace organic contaminants (TOrCs) in soil. Direct enantioselective separations were achieved on a Chirobiotic V2 column operated in polar ionic mode. Init... Read More about Multi-residue analysis of chiral and achiral trace organic contaminants in soil by accelerated solvent extraction and enantioselective liquid chromatography tandem-mass spectrometry..

Oral human papillomavirus infection in England and associated risk factors: a case control study. (2018)
Journal Article
HEARNDEN, V., MURDOCH, C., D'APICE, K., DUTHIE, S., HAYWARD, N.J. and POWERS, H.J. 2018. Oral human papillomavirus infection in England and associated risk factors: a case control study. BMJ open [online], 8(8), article number 022497. Available from: https://doi.org/10.1136/bmjopen-2018-022497

Objectives - This study was conducted to determine the prevalence of and associated risk factors for infection with oral high-risk human papillomavirus (HR-HPV) in adult participants within England, and to explore any association with oral mucosal bu... Read More about Oral human papillomavirus infection in England and associated risk factors: a case control study..

A systematic review of clinicians' views and experiences of direct-acting oral anticoagulants in the management of non-valvular atrial fibrillation. (2018)
Journal Article
GENERALOVA, D., CUNNINGHAM, S., LESLIE, S.J., RUSHWORTH, G.F., MCIVER, L. and STEWART, D. 2018. A systematic review of clinicians' views and experiences of direct-acting oral anticoagulants in the management of non-valvular atrial fibrillation. British journal of clinical pharmacology [online], 84(12), pages 2692-2703. Available from: https://doi.org/10.1111/bcp.13739

Introduction: While a plethora of systematic reviews have provided evidence of efficacy, effectiveness and safety of direct-acting oral anticoagulants (DOACs) in the management of non-valvular atrial fibrillation (AF), there has been little emphasis... Read More about A systematic review of clinicians' views and experiences of direct-acting oral anticoagulants in the management of non-valvular atrial fibrillation..

Unique corrosion resistance of ultrahigh pressure Mg-25Al binary alloys. (2018)
Journal Article
FENG, J., LI, H., DENG, K., FERNANDEZ, C., ZHANG, Q. and PENG, Q. 2018. Unique corrosion resistance of ultrahigh pressure Mg-25Al binary alloys. Corrosion science [online], 143, pages 229-239. Available from: https://doi.org/10.1016/j.corsci.2018.08.013

Differing from as-cast and solid-solution alloys with coarse eutectic phases (Mg17Al12), a single-phase structure is attained in Mg-25wt.%Al alloy after ultrahigh-pressure solid-solution (USS, 800 oC, 4GPa). This USSed Mg-25wt.%Al sample exhibits a p... Read More about Unique corrosion resistance of ultrahigh pressure Mg-25Al binary alloys..