All Outputs (857)

Differential pulse voltammetric determination of albendazole and mebendazole in pharmaceutical formulations based on modified sonogel carbon paste electrodes with perovskite-type LaFeO3 nanoparticles. (2016)
Journal Article
DE MACEDO, I.Y.L., GARCIA, L.F., DE SOUZA, A.R., DA SILVA, A.M.L., FERNANDEZ, C., SANTOS, M.D.G., MAGALHÃES, R.S., TORRES, I.M.S. and GIL, E.S. 2016. Differential pulse voltammetric determination of albendazole and mebendazole in pharmaceutical formulations based on modified sonogel carbon paste electrodes with perovskite-type LaFeO3 nanoparticles. Journal of the Electrochemical Society [online], 163(8), pages B428-B434. Available from: https://doi.org/10.1149/2.0661608jes

Benzimidazoles, such as albendazole (AB) and mebendazole (MB), are common anthelmintic agents, widely used throughout the world to combat parasitic diseases. The electroanalytical sensing of AB and MB based on Perovskite-Type LaFeO3 nanoparticles mod... Read More about Differential pulse voltammetric determination of albendazole and mebendazole in pharmaceutical formulations based on modified sonogel carbon paste electrodes with perovskite-type LaFeO3 nanoparticles..

Exploiting the antiparasitic activity of naphthalimides derivatives. (2016)
Journal Article
CRISTO, G., GASPAR, L., NORO, J., BAPTISTA, C., KONG THOO LIN, P., ALVES, M.J. and CORDEIRO-DA-SILVA, A. 2016. Exploiting the antiparasitic activity of naphthalimides derivatives. International journal of chemistry and pharmaceutical sciences [online], 4(1), pages 19-23. Available from: http://www.pharmaresearchlibrary.com/wp-content/uploads/2016/06/IJCPS2793.pdf

A set of 1,8-naphtalimides derivatives were synthesized and tested against three protozoans that cause important human diseases: Leishmania infantum, Trypanosomabrucei and Trypanosoma cruzi. Additionally, toxicity was determined by growth inhibition... Read More about Exploiting the antiparasitic activity of naphthalimides derivatives..

Correlation among physical and electrochemical behaviour of nanostructured electrolytic manganese dioxide from leach liquor and synthetic for aqueous asymmetric capacitor. (2016)
Journal Article
SUNDARAM, M.M., BISWAL, A., MITCHELL, D., JONES, R. and FERNANDEZ, C. 2016. Correlation among physical and electrochemical behaviour of nanostructured electrolytic manganese dioxide from leach liquor and synthetic for aqueous asymmetric capacitor. Physical chemistry chemical physics [online], 18(6), pp. 4711-4720. Available from: https://doi.org/10.1039/C5CP07141K

An attempt has been made to correlate the differences in structural parameters, surface areas, morphology etc. with the electrochemical capacitive behaviour of the EMDs. The nanostructured electrolytic manganese dioxides (EMD) have been synthesized t... Read More about Correlation among physical and electrochemical behaviour of nanostructured electrolytic manganese dioxide from leach liquor and synthetic for aqueous asymmetric capacitor..

Microbial diversity in the digestive tract of two different breeds of sheep. (2016)
Journal Article
DOUGLAS, J.-L., WORGAN, H.J., EASTON, G.L., PORET, L., WOLF, B.T., EDWARDS, A., DAVIES, E., ROSS, D. and MCEWAN, N.R. 2016. Microbial diversity in the digestive tract of two different breeds of sheep. Journal of applied microbiology [online], 120(5), pages 1382-1389. Available from: https://doi.org/10.1111/jam.13060

Aims: This work aims to determine the factors which play a role in establishing the microbial population throughout the digestive tract in ruminants and is necessary to enhance our understanding of microbial establishment and activity. Methods and Re... Read More about Microbial diversity in the digestive tract of two different breeds of sheep..

Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: recommendations for saturation divers. (2016)
Journal Article
DEB, S.K., SWINTON, P.A. and DOLAN, E. 2016. Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: recommendations for saturation divers. Extreme physiology and medicine [online], 5, article number 1. Available from: https://doi.org/10.1186/s13728-015-0042-9

Saturation diving is an occupation that involves prolonged exposure to a confined, hyperoxic, hyperbaric environment. The unique and extreme environment is thought to result in disruption to physiological and metabolic homeostasis, which may impact h... Read More about Nutritional considerations during prolonged exposure to a confined, hyperbaric, hyperoxic environment: recommendations for saturation divers..

A cross-sectional survey of the Maltese general public on medication wastage. (2016)
Journal Article
WEST, L.M., DIACK, L., CORDINA, M. and STEWART, D. 2016. A cross-sectional survey of the Maltese general public on medication wastage. International journal of clinical pharmacy [online], 38(2), pages 261-270. Available from: https://doi.org/10.1007/s11096-015-0233-x

Background Medication wastage is a global issue, with key public health implications in terms of safety, the environment and the economy. A recently conducted systematic review of the published literature identified a lack of focus on the views of he... Read More about A cross-sectional survey of the Maltese general public on medication wastage..

Isolation of macro-nuclear DNA from the rumen ciliate Entodinium caudatum. (2015)
Journal Article
YOUNG, K.W., THOMAS, N.A., DUVAL, S.M., NEWBOLD, J., FRIED, J., BROWN, D.S., HACKSTEIN, J.H.P., MICHALOWSKI, T. and MCEWAN, N.R. 2015. Isolation of macro-nuclear DNA from the rumen ciliate Entodinium caudatum. Endocytobiosis and cell research [online], 26, pages 50-55. Available from: https://zs.thulb.uni-jena.de/receive/jportal_jparticle_00355360

A method is described which allows isolation of macronuclear DNA from the rumen ciliate Entodinium caudatum. Ciliate cells were enriched from the total microbial population in the rumen of sheep with a single ciliate species present by sedimentation... Read More about Isolation of macro-nuclear DNA from the rumen ciliate Entodinium caudatum..

Lobes on Alnus glutinosa nodules contain a single major ribo-type of Frankia. (2015)
Journal Article
MCEWAN, N.R., SNELLING, T.J., COLLINS, T., GIRDWOOD, S.E., WILKINSON, T., DOUGAL, K., JONES, D.L. and GODBOLD, D.L. 2015. Lobes on Alnus glutinosa nodules contain a single major ribo-type of Frankia. Endocytobiosis and cell research [online], 26, pages 83-86. Available from: https://zs.thulb.uni-jena.de/receive/jportal_jparticle_00364367

This work investigated the microbial content of nodules from alders to determine how many ribotypes of Frankia were present and which, if any, other bacteria existed within nodes from the nodules. The bacterial content of alder nodules was investigat... Read More about Lobes on Alnus glutinosa nodules contain a single major ribo-type of Frankia..

Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles. (2015)
Journal Article
SEGUNDO, M.A., ABREU, V.L.R.G., OSORIO, M.V., NOGUEIRA, S., KONG THOO LIN, P., CORDEIRO-DA-SILVA, A. and LIMA, S.A.C. 2016. Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles. Journal of pharmaceutical and biomedical analysis [online], 120, pages 290-296. Available from: https://doi.org/10.1016/j.jpba.2015.12.033

A simple, sensitive and specific high-performance liquid chromatography method for the quantification of bisnaphthalimidopropyldiaminooctane (BNIPDaoct), a potent anti-Leishmania compound, incorporated into poly(d,l-lactide-co-glycolic acid) (PLGA) n... Read More about Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles..

Renal and bone adverse effects of a tenofovir-based regimen in the treatment of HIV-Infected children: a systematic review. (2015)
Journal Article
OKONKWO, R.I., WEIDMANN, A.E. and EFFA, E.E. 2016. Renal and bone adverse effects of a tenofovir-based regimen in the treatment of HIV-Infected children: a systematic review. Drug safety [online], 39(3), pages 209-218. Available from: https://doi.org/10.1007/s40264-015-0371-z

Introduction Tenofovir disoproxil fumarate (TDF)-containing regimens in the treatment of HIV-infected children have safety concerns with respect to renal and bone toxicity. Objective The aim of this study was to systematically review and critically a... Read More about Renal and bone adverse effects of a tenofovir-based regimen in the treatment of HIV-Infected children: a systematic review..

Yellow card reports associated with use of natural health products in children: an exploratory analysis. (2015)
Journal Article
NDU, O., STRATH, A. and DIACK, L. 2015. Yellow card reports associated with use of natural health products in children: an exploratory analysis. European journal of integrative medicine [online], 7(6), page 693. Available from: https://doi.org/10.1016/j.eujim.2015.11.013

Abstract of a presentation given at the Research council for complementary medicine 2015 conference (RCCM): demonstrating the value of integrative medicine, 10 September, London, UK.

Multi-residue analysis of 90 emerging contaminants in liquid and solid environmental matrices by ultra-high-performance liquid chromatography tandem mass spectrometry. (2015)
Journal Article
PETRIE, B., YOUDAN, J., BARDEN, R. and KASPRZYK-HORDERN, B. 2016. Multi-residue analysis of 90 emerging contaminants in liquid and solid environmental matrices by ultra-high-performance liquid chromatography tandem mass spectrometry. Journal of chromatography A [online], 1431, pages 64-78. Available from: https://doi.org/10.1016/j.chroma.2015.12.036

Reported here in is new analytical methodology for the determination of 90 emerging contaminants (ECs)in liquid environmental matrices (crude wastewater, final effluent and river water). The application of a novel buffer, ammonium fluoride improved s... Read More about Multi-residue analysis of 90 emerging contaminants in liquid and solid environmental matrices by ultra-high-performance liquid chromatography tandem mass spectrometry..

Controlled periodic illumination in semiconductor photocatalysis. (2015)
Journal Article
TOKODE, O., PRABHU, R., LAWTON, L.A. and ROBERTSON, P.K.J. 2015. Controlled periodic illumination in semiconductor photocatalysis. Journal of photochemistry and photobiology A: chemistry [online], 319-320, pages 96-106. Available from: https://doi.org/10.1016/j.jphotochem.2015.12.002

Controlled periodic illumination is a hypothesis postulated in the early 1990s for enhancing the efficiency of semiconductor photocatalytic reactions. This technique has been proposed to improve photocatalytic efficiency by the nature of photon intro... Read More about Controlled periodic illumination in semiconductor photocatalysis..

Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photcatalysis. (2015)
Journal Article
ZHANG, G., NI, C., HUANG, X., WELGARMAGE, A., LAWTON, L.A., ROBERTSON, P.K.J. and IRVINE, J.T.S. 2016. Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photcatalysis. Chemical communications [online], 52, pages 1673-1676. Available from: https://doi.org/10.1039/c5cc09075j

Photocatalytic conversion of cellulose to sugars and carbon dioxide with simultaneous production of hydrogen assisted by cellulose decomposition under UV or solar light irradiation was achieved upon immobilization of cellulose onto a TiO2 photocataly... Read More about Simultaneous cellulose conversion and hydrogen production assisted by cellulose decomposition under UV-light photcatalysis..

The role of ciliate protozoa in the rumen. (2015)
Journal Article
NEWBOLD, C.J., DE LA FUENTE, G. BELANCHE, A. RAMOS-MORALES, E. and MCEWAN, N.R. 2015. The role of ciliate protozoa in the rumen. Frontiers in microbiology [online], 6, Article 1313. Available from: https://doi.org/10.3389/fmicb.2015.01313

First described in 1843, Rumen protozoa with their striking appearance were assumed to be important for the welfare of their host. However, despite contributing up to 50% of the bio-mass in the rumen, the role of protozoa in rumen microbial ecosystem... Read More about The role of ciliate protozoa in the rumen..

Microneedle coating techniques for transdermal drug delivery. (2015)
Journal Article
HAJ-AHMAD, R., KHAN, H., ARSHAD, M.S., RASEKH, M., HUSSAIN, A., WALSH, S., LI, X., CHANG, M.-W. and AHMAD, Z. 2015. Microneedle coating techniques for transdermal drug delivery. Pharmaceutics [online], 7(4), pages 486-502. Available from: https://doi.org/10.3390/pharmaceutics7040486

Drug administration via the transdermal route is an evolving field that provides an alternative to oral and parenteral routes of therapy. Several microneedle (MN) based approaches have been developed. Among these, coated MNs (typically where drug is... Read More about Microneedle coating techniques for transdermal drug delivery..

Assessment of tigecycline prescription and patients' outcomes at three different hospitals in Saudi Arabia. (2015)
Journal Article
TOBAIQY, M., AL HUMAID, S., STEWART, D., ALOTAIBI, F.O., QURESHI, K.A., MACLURE, K., ALGHARIB, F., ALSMETI, A., ALSAQER, A. and ALMEMAN, A. 2015. Assessment of tigecycline prescription and patients' outcomes at three different hospitals in Saudi Arabia. Tropical journal of pharmaceutical research [online], 14(10), pages 1919-1926. Available from: https://doi.org/10.4314/tjpr.v14i10.26

The purpose of this study is to investigate tigecycline prescription and patient outcomes in the Kingdom of Saudi Arabia (KSA). A retrospective observational study was conducted in three KSA government hospitals, between January, 2013 and May, 2014.... Read More about Assessment of tigecycline prescription and patients' outcomes at three different hospitals in Saudi Arabia..

The use of theory in research. (2015)
Journal Article
STEWART, D. and KLEIN, S. 2016. The use of theory in research. International journal of clinical pharmacy [online], 38(3), pages 615-619. Available from: https://doi.org/10.1007/s11096-015-0216-y

All researchers should consider the theoretical basis for their studies very early on in the planning stage. The aim of this paper is to describe and discuss how theory (a 'comprehensive explanation of some aspect of nature that is supported by a bod... Read More about The use of theory in research..

An exploration of health professionals' experiences of medicines management in elderly, hospitalised patients in Abu Dhabi. (2015)
Journal Article
AL SHEMEILI, S., KLEIN, S., STRATH, A., FARES, S. and STEWART, D. 2016. An exploration of health professionals' experiences of medicines management in elderly, hospitalised patients in Abu Dhabi. International journal of clinical pharmacy [online], 38(1), pages 107-118. Available from: https://doi.org/10.1007/s11096-015-0212-2

Background Given the multiplicity of issues relating to medicines in the elderly, the structures and processes of medicines management should be clearly defined and described to optimise patient outcomes. There is a paucity of research which provides... Read More about An exploration of health professionals' experiences of medicines management in elderly, hospitalised patients in Abu Dhabi..

Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. (2015)
Journal Article
BARRON, G.A., GOUA, M., KURAOKA, I., BERMANO, G., IWAI, S. and KONG THOO LIN, P. 2015. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-biological interactions [online], 242, pages 307-315. Available from: https://doi.org/10.1016/j.cbi.2015.10.017

Bisnaphthalimidopropyl diaminodicyclohexylmethane (BNIPDaCHM) bisintercalates to DNA and is a potential anti-cancer therapeutic. In an attempt to elucidate the mechanism(s) underlying the potential of BNIPDaCHM; earlier work was extended to investiga... Read More about Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression..