In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells.

Ibie, C.; Knott, R.; Thompson, C.J.

doi:10.1016/j.ijpharm.2014.12.058

Developing an international interprofessional diabetes course turning the world blue for a day! (2015)
Presentation / Conference
DIACK, L., HAXTON, J., JOSEPH, S., MCFADYEN, M., WALKER, P., ABE, K., SUMETSU, M. and YASUI, H. 2015. Developing an international interprofessional diabetes course turning the world blue for a day! Presented at the 2015 RGU learning and teaching conference, 5 May 2015, Aberdeen, UK.

This poster describes the activity undertaken with students in Scotland (RGU) and Japan (University of Nagoya) to mark World Diabetes Day in November 2014. The activity was an interprofessional intervention, in which student teams from both countries... Read More about Developing an international interprofessional diabetes course turning the world blue for a day!.

Modeling the effect of KCL inhibition on the rheological properties of shale contaminated water based mud. (2015)
Journal Article
EKE, C.E. and EZENWEICHU, C.L. 2015. Modeling the effect of KCL inhibition on the rheological properties of shale contaminated water based mud. Petroleum and coal journal [online], 57(2), pages 194-198. Available from: https://www.vurup.sk/wp-content/uploads/dlm_uploads/2017/07/pc_1_2015_ezenweichu_316_kor.pdf

Water based muds are the most extensively used drilling muds. Their use is however limited, especially in shaley formations where it results to various degrees of wellbore instability. In such formations, oil based muds are often utilized due to... Read More about Modeling the effect of KCL inhibition on the rheological properties of shale contaminated water based mud..

Interprofessional student-run primary health clinics: implications for pharmacy education in Scotland. (2015)
Journal Article
WEIDMANN, A. E., PAMMETT, R., LANDRY, E. and JORGENSON, D., 2015. Interprofessional student-run primary health clinics: implications for pharmacy education in Scotland. Canadian Pharmacists Journal [online], 148(3), pages 156-159. Available from: https://doi.org/10.1177/1715163515578124

Introduction Interprofessional student run primary health care clinics have been a flagship model of health professional education in Canada for many years. The purpose of this study was to determine if there is support for implementing this educatio... Read More about Interprofessional student-run primary health clinics: implications for pharmacy education in Scotland..

Incidence, nature and causes of medication errors in hospitalised patients in Middle Eastern countries: a systematic review protocol. [Protocol] (2015)
Other
THOMAS, B., ROUF, P.A., AL HAIL, M., EL KASSEM, W., AL SAAD, D., SINGH, R., STEWART, D., PAUDYAL, V., MACLURE, K. and MCLAY, J. 2015. Incidence, nature and causes of medication errors in hospitalised patients in Middle Eastern countries: a systematic review protocol. [Protocol]. PROSPERO [online], item number CRD42015019693. Available from: https://doi.org/10.15124/CRD42015019693

The review will consider studies, which focus on errors in hospitalised patients (of any age or speciality) in any of the countries of the Middle East. Studies of hospital practitioners (or other key stakeholders) which capture data on causes of erro... Read More about Incidence, nature and causes of medication errors in hospitalised patients in Middle Eastern countries: a systematic review protocol. [Protocol].

Can selenium supplementation modify oxidative stress in-vitro? (2015)
Journal Article
LEIGHTON, D., GOUA, M., DOLAN, E., BURGESS, K. and BERMANO, G. 2015. Can selenium supplementation modify oxidative stress in-vitro? A role for selenium supplementation in the prevention of cardiovascular disease. Journal of inflammation [online], 12(Supplement 1): abstracts from the 1st Annual meeting of the Scottish Society of Cytomics (SCC), 25 September 2014, Aberdeen, UK, article P7. Available from: https://doi.org/10.1186/1476-9255-12-S1-P7

Two thirds of the UK population are either overweight or obese (body mass index (BMI) 25-29.9 and >30 kg/m2 respectively) and are typically characterised by systemic oxidative stress (OS); deemed to play a key role in cardiovascular disease (CVD) dev... Read More about Can selenium supplementation modify oxidative stress in-vitro?.

Antimicrobial stewardship activities in hospitals in Ireland and the United Kingdom: a comparison of two national surveys. (2015)
Journal Article
FLEMING, A., TONNA, A., O'CONNOR, S., BYRNE, S. and STEWART, D. 2015. Antimicrobial stewardship activities in hospitals in Ireland and the United Kingdom: a comparison of two national surveys. International journal of clinical pharmacy [online], 37(5), pages 776-781. Available from: https://doi.org/10.1007/s11096-015-0114-3

Best practice guidelines recommend that a multidisciplinary Antimicrobial Management Team (AMT) conduct antimicrobial stewardship (AMS) activities in hospitals. In order to continuously improve AMS activities in Irish hospitals it is important to ben... Read More about Antimicrobial stewardship activities in hospitals in Ireland and the United Kingdom: a comparison of two national surveys..

Promoting weight management services in community pharmacy: perspectives of the pharmacy team in Scotland. (2015)
Journal Article
WEIDMANN, A.E., MACLURE, K., MARSHALL, S., GRAY, G. and STEWART, D. 2015. Promoting weight management services in community pharmacy: perspectives of the pharmacy team in Scotland. International journal of clinical pharmacy [online], 37(4), pages 599-606. Available from: https://doi.org/10.1007/s11096-015-0102-7

Background Obesity has reached pandemic levels with more than 1.4 billion adults affected worldwide. While there is a need to systematically develop and evaluate community pharmacy based models of weight management, it is imperative to describe and u... Read More about Promoting weight management services in community pharmacy: perspectives of the pharmacy team in Scotland..

A mixed methods investigation into aspects of medication wastage in Malta. (2015)
Thesis
WEST, L.M. 2015. A mixed methods investigation into aspects of medication wastage in Malta. Robert Gordon University, PhD thesis.

Reducing medication wastage is a paramount objective in promoting appropriate utilisation of finite resources and preventing negative consequences. The aim of this research was to investigate aspects of medication wastage in Malta by applying mixed m... Read More about A mixed methods investigation into aspects of medication wastage in Malta..

The role of selenium supplementation in cardiovascular disease prevention: an in vitro study to identify the molecular mechanism(s). (2015)
Presentation / Conference
LEIGHTON, D., GOUA, M., DOLAN, E., BURGESS, K. and BERMANO, G. 2015. The role of selenium supplementation in cardiovascular disease prevention: an in vitro study to identify the molecular mechanism(s). Presented at the 2015 Nutrition Society Scottish section meeting: diet, gene regulation and metabolic disease, 25-26 March 2015, Aberdeen, UK.

Obesity is a worldwide epidemic, with two thirds of the UK population either overweight or obese (body mass index (BMI) 25–29·9 and >30 kg/m2 respectively). Obesity is characterised by systemic oxidative stress (OS), which itself results from chronic... Read More about The role of selenium supplementation in cardiovascular disease prevention: an in vitro study to identify the molecular mechanism(s)..

Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. (2015)
Journal Article
IBIE, C.O., THOMPSON, C.J. and KNOTT, R. 2015. Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine. Colloid and polymer science [online], 293(6), pages 1737-1748. Available from: https://doi.org/10.1007/s00396-015-3561-4

Polyallylamine (Paa) was quaternised by methylation of its primary amines using methyl iodide to yield quaternised Paa (QPaa). Average level of polymer quaternisation was determined by elemental analysis and was found to be 72 ± 2mol%. Subsequent thi... Read More about Synthesis, characterisation and in vitro evaluation of novel thiolated derivatives of polyallylamine and quaternised polyallylamine..

Now it's over to you: a workbook approach. (2015)
Book Chapter
MCFADYEN, M.C.E. 2015. Now it's over to you: a workbook approach. In Thomas, L. (ed.) Compendium of effective practice in directed independent learning. York: Higher Education Academy [online], pages 85-87. Available from: https://www.advance-he.ac.uk/knowledge-hub/compendium-effective-practice-directed-independent-learning

During the oncology topic within the third year 'Clinical Pharmacology and Therapeutics 2' module (CPT2) of the MPharm at Robert Gordon University (RGU), it quickly became apparent that students had difficulty in placing complex concepts into context... Read More about Now it's over to you: a workbook approach..

An exploratory study of the views of community pharmacy staff on the management of patients with undiagnosed skin problems. (2015)
Journal Article
TUCKER, R. and STEWART, D. 2015. An exploratory study of the views of community pharmacy staff on the management of patients with undiagnosed skin problems. International journal of pharmacy practice [online], 23(6), pages 390-398. Available from: https://doi.org/10.1111/IJPP.12179

Objective: The aim of this study was to explore pharmacist and medicine counter assistant (MCA) perceptions of community pharmacy management of patients presenting with symptomatic skin problems. Methods: The study involved semi-structured telephone... Read More about An exploratory study of the views of community pharmacy staff on the management of patients with undiagnosed skin problems..

Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands and Western Isles. (2015)
Journal Article
RUSHWORTH, G.F., DIACK, L., MACROBBIE, A., MUNOZ, S.-A., PFLEGER, S., STEWART, D. 2015. Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands and Western Isles. Public health [online], 129(3), pages 244-251. Available from: https://doi.org/10.1016/j.puhe.2015.01.005

Objectives: Sparsely populated areas are potentially predisposed to health inequalities due to limited access to services. This study aimed to explore and describe issues of access to medicines and related advice experienced by residents of the Scott... Read More about Access to medicines in remote and rural areas: a survey of residents in the Scottish Highlands and Western Isles..

A study on temporal trends and estimates of fate of Bisphenol A in agricultural soils after sewage sludge amendment. (2015)
Journal Article
ZHANG, Z., LE VELLY, M., RHIND, S.M., KYLE, C.E., HOUGH, R.L., DUFF, E.I. and MCKENZIE, C. 2015. A study on temporal trends and estimates of fate of Bisphenol A in agricultural soils after sewage sludge amendment. Science of the total environment [online], 515-516, pages 1-11. Available from: https://doi.org/10.1016/j.scitotenv.2015.01.053

Temporal concentration trends of BPA in soils were investigated following sewage sludge application to pasture (study 1: short term sludge application; study 2: long term multiple applications over 13years). The background levels of BPA in control so... Read More about A study on temporal trends and estimates of fate of Bisphenol A in agricultural soils after sewage sludge amendment..

Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana. (2015)
Journal Article
AMPONSAH, A.O., VOSPER, H. and MARFO, A.F.A., 2015. Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana. Malaria research and treatment [online], 2015, Article ID 452539. Available from: https://doi.org/10.1155/2015/452539

Our aim was to measure the adherence to Artemisinin based Combination Therapy and to determine patient related factors that affect adherence. Three hundred (300) patients receiving ACT treatment dispensed from the community pharmacy were randomly sel... Read More about Patient related factors affecting adherence to antimalarial medication in an urban estate in Ghana..

Deferiprone, a non-toxic reagent for determination of iron in samples via sequential injection analysis. (2015)
Journal Article
PRAGOURPUN, K., SAKEE, U., FERNANDEZ, C. and KRUANETR, S. 2015. Deferiprone, a non-toxic reagent for determination of iron in samples via sequential injection analysis. Spectrochimica acta, part A: molecular and biomolecular spectroscopy [online], 142, pages 110-117. Available from: https://doi.org/10.1016/j.saa.2015.01.081

We present for the first time the use of deferiprone as a non-toxic complexing agent for the determination of iron by sequential injection analysis in pharmaceuticals and food samples. The method was based on the reaction of Fe(III) and deferiprone i... Read More about Deferiprone, a non-toxic reagent for determination of iron in samples via sequential injection analysis..

Conductance studies of aqueous ionic liquids solutions [emim][BF4] and [bmim][BF4] at temperatures from (283.15 to 318.15) K. (2015)
Journal Article
BORUŃ, A., FERNANDEZ, C. and BALD, A. 2015. Conductance studies of aqueous ionic liquids solutions [emim][BF4] and [bmim][BF4] at temperatures from 283.15 to 318.15 K. International journal of electrochemical science [online], 10(3), pages 2120-2129. Available from: https://doi.org/10.1016/S1452-3981(23)04834-4

We present for the first time the determination of molar conductances, Lambda, of ionic liquids solutions (ILs) such as 1-ethyl-3-methylimidazolium tetrafluoroborate [emim][BF4] and 1-butyl-3-methylimidazolium tetrafluoroborate [bmim][BF4] as a funct... Read More about Conductance studies of aqueous ionic liquids solutions [emim][BF4] and [bmim][BF4] at temperatures from (283.15 to 318.15) K..

Interagency adult support and protection practice of police and health and social care professionals: a realistic evaluation approach. (2015)
Report
JOSEPH, S., DIACK, L., HEYMAN, I., KLEIN, S., MCCLUSKEY, S., WOOLNOUGH, P., FALCONER, M., REDDISH, A. and MACLEAN, E. 2015. Interagency adult support and protection practice of police and health and social care professionals: a realistic evaluation approach. SIPR research summary number 19. Dundee: Scottish Institute for Policing Research, School of Social Sciences, University of Dundee [online]. Available from: http://www.sipr.ac.uk/Plugin/Publications/assets/files/Research_Summary_19.pdf

The purpose of this project was to investigate the interagency Adult Support and Protection practices of police, health and social care professionals in Scotland by means of a Realistic Evaluation Approach. The study comprised of two specific phases.... Read More about Interagency adult support and protection practice of police and health and social care professionals: a realistic evaluation approach..

Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. (2014)
Journal Article
BARRON, G.A., BORDET, E., GOUA, M. and BERMANO. G. 2014. Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system. Current angiogenesis [online], 3(3), pages 152-163. Available from: https://doi.org/10.2174/2211552803666141113211829

Increased levels of inflammatory markers such as tumour necrosis factor-α (TNFα) and interleukin- 6 (IL-6) have been associated with formation of new blood vessels, or angiogenesis, and linked to chronic inflammation in obesity. This study aimed to e... Read More about Modulation of angiogenesis by inflammatory markers and the role of matrix metalloproteinases in an endothelial cell/fibroblast co-culture system..

In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. (2014)
Journal Article
IBIE, C., KNOTT, R. and THOMPSON, C.J. 2015. In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells. International journal of pharmaceutics [online], 479(1), pages 103-117. Available from: https://doi.org/10.1016/j.ijpharm.2014.12.058

The biocompatibility and cellular uptake of polymer, insulin polyelectrolyte complexes (PECs) prepared using polyallylamine-based polymers was evaluated in-vitro using Caco-2 cell monolayers as a predictive model for human small intestinal epithelial... Read More about In-vitro evaluation of the effect of polymer structure on uptake of novel polymer-insulin polyelectrolyte complexes by human epithelial cells..

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