Dr Sarah Walsh s.walsh@rgu.ac.uk
Research Fellow
sFRPs as a novel modulator of diastolic heart failure
People Involved
Professor Cherry Wainwright c.wainwright@rgu.ac.uk
Professor
Project Description
Following a heart attack, or because of persistently high blood pressure the heart is damaged and has to work harder to circulate blood around the body. This condition is known as heart failure. In the UK alone, 500,000 people have heart failure resulting in 150,000 inpatient episodes in 2012/2013.
The aims of this research project are to increase our understanding of what roles sFRPs play in the heart and determine whether changes in the activity of sFRPs are associated with diastolic heart failure and investigate whether sFRPs represent a novel therapy for the treatment of this condition.
In partnership with Astra Zeneca
Type of Project | Project |
---|---|
Status | Project Complete |
Funder(s) | Medical Research Council |
Value | £95,795.00 |
Project Dates | Oct 1, 2017 - Dec 31, 2021 |
Partner Organisations | AstraZeneca |
You might also like
The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2 Jul 1, 2017 - Dec 31, 2019
Medicinal use of natural products, such as, extracts from plants have existed for many years particularly in China and are now widely available around the world. Several different types of cancer including breast cancer are becoming insensitive and r...
Read More about The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2.
The application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases Oct 1, 2014 - Jul 31, 2020
Neurodegenerative diseases such as Alzheimer's and Parkinsonism currently affect a large proportion of the world population, and this is expected to double every 20 years to 81.1 million by 2040. One contributing factor to this predicted number in ne...
Read More about The application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases.
Defining the emerging roles of GPR55 Oct 1, 2019 - Feb 4, 2023
The G-protein coupled receptor (GPCR) superfamily play crucial roles in cell communication. Given their involvement in neurological disorders, inflammatory and metabolic diseases, diabetes and cardiac dysfunction they represent the largest and most s...
Read More about Defining the emerging roles of GPR55.
Extracting added value from the Seaweed Industry - a search for novel anti-obesity agents Oct 1, 2018 - Dec 31, 2022
Seaweed farming is a growing industry in the UK, with the majority of the biomass being used for the extraction of high yield products such as aliginates, or for use as biofuels.
However, a significant amount of the biomass remains u...
Read More about Extracting added value from the Seaweed Industry - a search for novel anti-obesity agents.