Outputs (25)

Selenium and viral infection: are there lessons for COVID-19? (2020)
Journal Article
BERMANO, G., MÉPLAN, C., MERCER, D.K. and HESKETH, J.E. 2021. Selenium and viral infection: are there lessons for COVID-19? British journal of nutrition [online], 125(6), pages 618-627. Available from: https://doi.org/10.1017/S0007114520003128

Selenium (Se) is a micronutrient that is essential for human health. Sub-optimal Se status is common, occurring in a significant proportion of the population across the world, including parts of Europe and China. Human and animal studies have shown t... Read More about Selenium and viral infection: are there lessons for COVID-19?.

Adipocytokines and their relationship to endometrial cancer risk: a systematic review and meta-analysis. (2020)
Journal Article
ELLIS, P.E., BARRON, G.A., and BERMANO, G. 2020. Adipocytokines and their relationship to endometrial cancer risk: a systematic review and meta-analysis. Gynecologic oncology [online], 158(2), pages 507-516. Available from: https://doi.org/10.1016/j.ygyno.2020.05.033

Objective:- To investigate the association between circulating levels of adipocytokines (adiponectin, leptin, tumour necrosis factor alpha (TNFα), interleukin 6 (IL-6)) and growth factors (insulin-like growth factor I (IGF-I) and II (IGF-II)), and th... Read More about Adipocytokines and their relationship to endometrial cancer risk: a systematic review and meta-analysis..

Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations. (2019)
Journal Article
BHATTA, P., BERMANO, G., WILLIAMS, H.C. and KNOTT, R.M. 2020. Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations. Genomics [online], 112(2), pages 1795-1803. Available from: https://doi.org/10.1016/j.ygeno.2019.10.011

To determine the association of peroxisome proliferator activated receptor gamma coactivator 1 Gly482Ser variant with components of metabolic syndrome. Materials and methods:- A systematic search was carried out using Web of Science, PubMed, EMBASE a... Read More about Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations..

GST-4-dependent suppression of neurodegeneration in C. elegans models of Parkinson’s and Machado-Joseph Disease by rapeseed pomace extract supplementation. (2019)
Journal Article
POHL, F., TEIXEIRA-CASTRO, A., COSTA, M.D., LINDSAY, V., FIÚZA-FERNANDES, J., GOUA, M., BERMANO, G., RUSSELL, W., MACIEL, P. and KONG THOO LIN, P. 2019. GST-4-dependent suppression of neurodegeneration in C. elegans models of Parkinson’s and Machado-Joseph Disease by rapeseed pomace extract supplementation. Frontiers in neuroscience [online], 13, article ID 1091. Available from: https://doi.org/10.3389/fnins.2019.01091

Genetic mutations and aging-associated oxidative damage underlie the onset and progression of neurodegenerative diseases, like Parkinson’s disease (PD) and Machado-Joseph disease (MJD). Natural products derived from plants have been regarded as impor... Read More about GST-4-dependent suppression of neurodegeneration in C. elegans models of Parkinson’s and Machado-Joseph Disease by rapeseed pomace extract supplementation..

Açaí (Euterpe oleracea Martius) supplementation in the diet during gestation and lactation attenuates liver steatosis in dams and protects offspring. (2019)
Journal Article
BARBOSA, P.O., DE SOUZA, M.O., PAIVA, D.P.D., SILVA, M.E., LIMA, W.G., BERMANO, G. and FREITAS, R.N. 2020. Açaí (Euterpe oleracea Martius) supplementation in the diet during gestation and lactation attenuates liver steatosis in dams and protects offspring. European journal of nutrition [online], 59(5), pages 1595-1908. Available from: https://doi.org/10.1007/s00394-019-02040-2

Purpose: Maternal high-fat diet affects offspring and can induce metabolic disorders such as non-alcoholic fatty liver disease (NAFLD). New therapeutic strategies are being investigated as way to prevent or attenuate this condition. The objective of... Read More about Açaí (Euterpe oleracea Martius) supplementation in the diet during gestation and lactation attenuates liver steatosis in dams and protects offspring..

Interaction of NKX3.1 and SELENOP genotype with prostate cancer recurrence. (2018)
Journal Article
DONADIO, J.L.S., LIU, L., FREEMAN, V.L., EKOUE, D.N., DIAMOND, A.M. and BERMANO, G. 2018. Interaction of NKX3.1 and SELENOP genotype with prostate cancer recurrence. Prostate [online], 79(5), pages 462-467. Available from: https://doi.org/10.1002/pros.23752

Background: NKX3.1 is a tumor suppressor frequently lost in prostate cancer. Previous studies by others indicated that the risks associated with reduced NKX3.1 levels can be enhanced by anti-oxidant supplementation. Selenium is an essential component... Read More about Interaction of NKX3.1 and SELENOP genotype with prostate cancer recurrence..

Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation. (2017)
Journal Article
BARRON, G.A., GOUA, M., WAHLE, K.W.J. and BERMANO, G. 2017. Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation. Oncology reports [online], 38(3), pages 1886-1894. Available from: https://doi.org/10.3892/or.2017.5803

The present study exploited a versatile in vitro endothelial cell/fibroblast co-culture cell system to investigate the association between angiogenesis and breast cancer by comparing the capacity of plasma from women with breast cancer and age-matche... Read More about Circulating levels of angiogenesis-related growth factors in breast cancer: a study to profile proteins responsible for tubule formation..

Revalorisation of rapeseed pomace extracts: an in vitro study into its anti-oxidant and DNA protective properties. (2017)
Journal Article
POHL, F., GOUA, M., BERMANO, G., RUSSELL, W.R., SCOBBIE, L., MACIEL, P. and KONG THOO LIN, P. 2018. Revalorisation of rapeseed pomace extracts: an in vitro study into its anti-oxidant and DNA protective properties. Food chemistry [online], 239, pages 323-332. Available from: https://doi.org/10.1016/j.foodchem.2017.06.129

Rapeseed pomace (RSP) is a waste product obtained after edible oil production from Brassica napus. Analysis of ubiquitous secondary metabolites in RSP samples (two breeds, harvested in 2012/2014 respectively from North East of Scotland) and their eth... Read More about Revalorisation of rapeseed pomace extracts: an in vitro study into its anti-oxidant and DNA protective properties..

Novel bisnaphthalimidopropyl (BNIPs) derivatives as anticancer compounds targeting DNA in human breast cancer cells. (2016)
Journal Article
KOPSIDA, M., BARRON, G.A. BERMANO, G., KONG THOO LIN, P. and GOUA, M. 2016. Novel bisnaphthalimidopropyl (BNIPs) derivatives as anticancer compounds targeting DNA in human breast cancer cells. Organic and biomolecular chemistry [online], 14(41), pages 9780-9789. Available from: https://doi.org/10.1039/C6OB01850E

Bisnaphthalimidopropyl (BNIP) derivatives are a family of compounds that exert anti-cancer activities in vitro and, according to previous studies, variations in the linker sequence have increased their DNA binding and cytotoxic activities. By modifyi... Read More about Novel bisnaphthalimidopropyl (BNIPs) derivatives as anticancer compounds targeting DNA in human breast cancer cells..

Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. (2015)
Journal Article
BARRON, G.A., GOUA, M., KURAOKA, I., BERMANO, G., IWAI, S. and KONG THOO LIN, P. 2015. Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression. Chemico-biological interactions [online], 242, pages 307-315. Available from: https://doi.org/10.1016/j.cbi.2015.10.017

Bisnaphthalimidopropyl diaminodicyclohexylmethane (BNIPDaCHM) bisintercalates to DNA and is a potential anti-cancer therapeutic. In an attempt to elucidate the mechanism(s) underlying the potential of BNIPDaCHM; earlier work was extended to investiga... Read More about Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression..