Outputs (1435)

An analysis of the development of family health nursing in Scotland through policy and practice 1998-2006. (2007)
Thesis
MACDUFF, C. 2007. An analysis of the development of family health nursing in Scotland through policy and practice 1998-2006. Robert Gordon University, PhD thesis.

In 1998 World Health Organisation Europe outlined a vision of a new community-based nurse called the Family Health Nurse (FHN) who would help individuals, families and communities to cope with illness and to improve their health. Scotland was the fir... Read More about An analysis of the development of family health nursing in Scotland through policy and practice 1998-2006..

The emotional wellbeing of young people: final report of phase one of a 'Choose Life' research project in Aberdeenshire (March 2004-March 2007). (2007)
Report
LOVE, J.G., SUTTON, P.W., WILLIAMS, H., MAYRHOFER, A.M., YUILL, C., LOVE, A.P. and MILLMAN, Y. 2007. The emotional wellbeing of young people: final report of phase one of a 'Choose Life' research project in Aberdeenshire (March 2004-March 2007). Aberdeen: Robert Gordon University.

The research was commissioned by the Aberdeenshire Community Planning Partnership in 2004 as part of its Choose Life Local Implementation Plan. The research has sought to address objectives 1 and 7 in the national Choose Life strategy, focusing on Ea... Read More about The emotional wellbeing of young people: final report of phase one of a 'Choose Life' research project in Aberdeenshire (March 2004-March 2007)..

Molecular mechanisms of nutrient mediated regulation of hypoxia inducible factor -1a(HIF-1a) in endothelial cells. (2007)
Thesis
HECTOR, E.E. 2007. Molecular mechanisms of nutrient mediated regulation of hypoxia inducible factor -1a(HIF-1a) in endothelial cells. Robert Gordon University, PhD thesis.

Poorly-controlled diabetes mellitus is associated with the development of chronic vascular complications, which cause morbidity and premature mortality. Many studies have highlighted that maintenance of normal blood glucose levels in all people with... Read More about Molecular mechanisms of nutrient mediated regulation of hypoxia inducible factor -1a(HIF-1a) in endothelial cells..

The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1α(βS*,δS*),2α,6α,8β- (R*),8aα]]-1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8- (2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)butyl ester), reduces splenocyte adhesion and reactive oxygen species generation in normal and atherosclerotic mice. (2007)
Journal Article
DEVER, G., SPICKETT, C.M., KENNEDY, S., RUSH, C., TENNANT, G., MONOPOLI, A. and WAINWRIGHT, C.L. 2007. The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1α(βS*,δS*),2α,6α,8β- (R*),8aα]]-1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8- (2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)butyl ester), reduces splenocyte adhesion and reactive oxygen species generation in normal and atherosclerotic mice. Journal of pharmacology and experimental therapeutics [online], 320(1), pages 419-426. Available from: https://doi.org/10.1124/jpet.106.109298

Statins possess anti-inflammatory effects that may contribute to their ability to slow atherogenesis, whereas nitric oxide (NO) also influences inflammatory cell adhesion. This study aimed to determine whether a novel NO-donating pravastatin derivati... Read More about The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1α(βS*,δS*),2α,6α,8β- (R*),8aα]]-1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8- (2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)butyl ester), reduces splenocyte adhesion and reactive oxygen species generation in normal and atherosclerotic mice..

The experience of young carers in the context of a range of parental conditions: physical disability, mental health problems and substance misuse. (2006)
Thesis
CHRISTIE, E. 2006. The experience of young carers in the context of a range of parental conditions: physical disability, mental health problems and substance misuse. Robert Gordon University, PhD thesis.

The current study set out to explore the affect and significance of differing parental conditions on the experiences commonly reported by young carers. Previous studies on young caring have reflected on the impacts of caring for parents with particul... Read More about The experience of young carers in the context of a range of parental conditions: physical disability, mental health problems and substance misuse..

Fatty acid and phospholipid chlorohydrins cause cell stress and endothelial adhesion. (2006)
Journal Article
DEVER, G., WAINWRIGHT, C. L., KENNEDY, S. and SPICKETT, C. M. 2006. Fatty acid and phospholipid chlorohydrins cause cell stress and endothelial adhesion. Acta biochimica polonica [online], 53(4), pages 761-768. Available from: https://doi.org/10.18388/abp.2006_3304

The oxidation of low-density lipoprotein (LDL) is thought to contribute to atherogenesis, which is an inflammatory disease involving activation of phagocytic cells. Myeloperoxidase, an enzyme which is able to produce hypochlorous acid (HOCl), is rele... Read More about Fatty acid and phospholipid chlorohydrins cause cell stress and endothelial adhesion..

Ethics and physiological testing. (2006)
Book Chapter
OLIVIER, S. 2007. Ethics and physiological testing. In Winter, E.M., Jones, A.M., Davison, R.C.R., Bromley, P.D. and Mercer, T.H. (eds.) Sport and exercise physiology testing guidelines: the British Association of Sport and Exercise Sciences guide. Abingdon: Routledge [online], volume 1: sport testing, chapter 4, pages 30-38. Available from: https://doi.org/10.4324/9780203966846

What is it to behave in an ethical manner as a researcher? The term 'ethics' suggests a set of standards by which behaviour is regulated, and these standards help us to decide what is acceptable in terms of pursuing our aims, as well as helping us to... Read More about Ethics and physiological testing..

Bereavement and bereavement care: consultation and mapping of practice (phase 2). (2006)
Report
STEPHEN, A.I., WIMPENNY, P., UNWIN, R., WORK, F., MACDUFF, C., DEMPSTER, P., WILCOCK, S.E. and BROWN, A.M. 20O6. Bereavement and bereavement care: consultation and mapping of practice (phase 2). Final report. Aberdeen: Robert Gordon University. Hosted on OpenAIR. Available from:

Looking for information on bereavement care, other than reading material in professional or academic journals can be a daunting task. A search of the internet provides a significant 1,116,403 hits, which range from general information, through bereav... Read More about Bereavement and bereavement care: consultation and mapping of practice (phase 2)..

Primary care staff's views and experiences related to routinely advising patients about physical activity: a questionnaire survey (2006)
Journal Article
DOUGLAS, F., TORRANCE, N., VAN TEIJLINGEN, E., MELONI, S. and KERR, A. 2006. Primary care staff's views and experiences related to routinely advising patients about physical activity: a questionnaire survey. BMC public health [online], 6, article 138. Available from: https://doi.org/10.1186/1471-2458-6-138

Background: United Kingdom public health policy has recently re-emphasised the role of primary health care professionals in tackling increasing levels of physical inactivity within the general population. However, little is known about the impact tha... Read More about Primary care staff's views and experiences related to routinely advising patients about physical activity: a questionnaire survey.

A follow-up study of professionals' perspectives on the development of family health nursing in Scotland: a questionnaire survey. (2006)
Journal Article
MACDUFF, C. 2006. A follow-up study of professionals' perspectives on the development of family health nursing in Scotland: a questionnaire survey. International journal of nursing studies [online], 43(3), pages 345-356. Available from: https://doi.org/10.1016/j.ijnurstu.2005.05.004

Background: In 1998 the World Health Organisation Europe introduced the Family Health Nurse concept. The envisaged role of this community-based nurse was seen as multi-faceted and included helping individuals, families and communities to cope with il... Read More about A follow-up study of professionals' perspectives on the development of family health nursing in Scotland: a questionnaire survey..

Thinking around abdominal obesity and cardiovascular risk. (2006)
Journal Article
BROOM, I. 2006. Thinking around abdominal obesity and cardiovascular risk. British journal of diabetes and vascular disease, 6(2), pages 58-61.

Obesity, particularly intra-abdominal (visceral) obesity, is a leading cause of cardiovascular disease (CVD), insulin resistance, type 2 diabetes, dyslipidaemia, inflammation and thrombosis. A useful indicator for visceral fat is waist circumference,... Read More about Thinking around abdominal obesity and cardiovascular risk..

The progress of family health nursing in remote and rural Scotland. (2005)
Journal Article
MACDUFF, C. 2005. The progress of family health nursing in remote and rural Scotland. British journal of community nursing [online], 10(12), pages 558-562. Available from: https://doi.org/10.12968/bjcn.2005.10.12.20150

Since 2001 the World Health Organization Europe's family health nurse (FHN) role has been developing in remote and rural areas of Scotland. In 2003, an independent evaluation identified a need for facilitation of the FHN role and family-health orient... Read More about The progress of family health nursing in remote and rural Scotland..

The effect of NCX4016 [2-acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl ester] on the consequences of ischemia and reperfusion in the streptozotocin diabetic rat. (2005)
Journal Article
BURKE, S.G., WAINWRIGHT, C.L., VOJNOVIC, I., WARNER, T., WATSON, D.G. and FURMAN, B.L. 2006. The effect of NCX4016 [2-acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl ester] on the consequences of ischemia and reperfusion in the streptozotocin diabetic rat. Journal of pharmacology and experimental therapeutics [online], 316(3), pages 1107-1114. Available from: https://doi.org/10.1124/jpet.105.096339

The aim of this study was to assess the effect of chronic administration of NCX4016 [2 acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl ester], a nitric oxide-releasing aspirin derivative on the consequences of coronary artery occlusion in streptozotocin-... Read More about The effect of NCX4016 [2-acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl ester] on the consequences of ischemia and reperfusion in the streptozotocin diabetic rat..

The emotional well-being of young people: a review of the literature. (2005)
Preprint / Working Paper
SUTTON, P.W., LOVE, J.G., BELL, J., CHRISTIE, E., MAYRHOFER, A., MILLMAN, Y., WILLIAMS, H. and YUILL, C. 2005. The emotional well-being of young people: a review of the literature. Aberdeen: Robert Gordon University [online]. Available from: https://openair.rgu.ac.uk

Suicide is increasingly described by governments and policy-makers as a global public health problem. Between 1950 and 1995 global suicide rates have increased by 60%. In recent years concerns have been expressed in Scotland and the UK about rising s... Read More about The emotional well-being of young people: a review of the literature..

An evaluation of the first year of family health nursing practice in Scotland. (2005)
Journal Article
MACDUFF, C. and WEST, B.J.M. 2005. An evaluation of the first year of family health nursing practice in Scotland. International journal of nursing studies [online], 42(1), pages 47-59. Available from: https://doi.org/10.1016/j.ijnurstu.2004.05.003

Scotland has led enactment of the new World Health Organisation (Europe) Family Health Nurse (FHN) concept. This paper presents research which evaluated the initial operation and impact of the role in remote and rural regions of Scotland. Through use... Read More about An evaluation of the first year of family health nursing practice in Scotland..

An evaluation of an educational programme to prepare family health nurses. (2004)
Journal Article
MACDUFF, C. and WEST, B.J.M. 2004. An evaluation of an educational programme to prepare family health nurses. Nurse education today [online], 24(7), pages 575-583. Available from: https://doi.org/10.1016/j.nedt.2004.08.001

In 1998 the World Health Organisation (WHO) Europe proposed a new type of community based nurse called the family health nurse (FHN). Although it was initially envisaged that 18 European countries would take part in the development of the FHN role th... Read More about An evaluation of an educational programme to prepare family health nurses..

Cytochrome P450 CYP1B1 activity in renal cell carcinoma. (2004)
Journal Article
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2004. Cytochrome P450 CYP1B1 activity in renal cell carcinoma. British journal of cancer [online], 91, pages 966-971. Available from: https://doi.org/10.1038/sj.bjc.6602053

Renal cell carcinoma (RCC) is the most common malignancy of the kidney and has a poor prognosis due to its late presentation and resistance to current anticancer drugs. One mechanism of drug resistance, which is potentially amenable to therapeutic in... Read More about Cytochrome P450 CYP1B1 activity in renal cell carcinoma..

Anti-cancer drug interaction with cytochrome P450 CYP1B1. (2003)
Presentation / Conference Contribution
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2003. Anti-cancer drug interaction with cytochrome P450 CYP1B1. Presented at the 2003 British cancer research meeting (BCRM 2003), 2-5 July 2003, Bournemouth, UK.

One mechanism potentially amenable to chemotherapeutic intervention involves cytochrome P450 CYP1B1. Our research has established the concept of over-expression of individual forms of cytochrome P450 - in particular CYP1B1 - in a range of solid tumou... Read More about Anti-cancer drug interaction with cytochrome P450 CYP1B1..

The managed entry of new drugs into a National Health Service: a case study for Malta. (2003)
Thesis
BONANNO, P.V. 2003. The managed entry of new drugs into a National Health Service: a case study for Malta. Robert Gordon University, PhD thesis.

The research question was to determine if it is possible to develop a systematic approach to the managed entry of new drugs into a National Health Service( NHS), using Malta as a case study. In early 1999, Malta had major problems with the managed en... Read More about The managed entry of new drugs into a National Health Service: a case study for Malta..

Qualitative research in sport sciences: is the biomedical ethics model applicable? (2003)
Journal Article
OLIVIER, S. and FISHWICK, L. 2003. Qualitative research in sport sciences: is the biomedical ethics model applicable? Forum: qualitative social research [online], 4(1), article number 12. Available from: https://doi.org/10.17169/fqs-4.1.754

Research in sports science has historically been grounded in positivist traditions. This means that ethics committees may not be adequately sensitized to the ethical problems posed by qualitative research. Qualitative researchers may thus be disadvan... Read More about Qualitative research in sport sciences: is the biomedical ethics model applicable?.