Outputs (1431)

Correcting calf girth discriminates the incidence of falling but not bone mass by broadband ultrasound attenuation in elderly female subjects. (2002)
Journal Article
STEWART, A.D., STEWART, A. and REID, D.M. 2002. Correcting calf girth discriminates the incidence of falling but not bone mass by broadband ultrasound attenuation in elderly female subjects. Bone [online], 31(1), pages 195-198. Available from: https://doi.org/10.1016/S8756-3282(02)00811-6

Calf circumference has been cited as an independent risk factor for hip fracture. Correcting this measured girth for subcutaneous adipose tissue or fluid accumulation provides a more valid estimate of lean tissue, but has not been reported in elderly... Read More about Correcting calf girth discriminates the incidence of falling but not bone mass by broadband ultrasound attenuation in elderly female subjects..

Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. (2002)
Presentation / Conference Contribution
ROONEY, P.H., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. Presented at the 184th Meeting of the Pathological Society of Great Britain and Ireland, 2-5 July 2002, Dublin, Ireland.

Detection of gene amplification is a process that is recognised as a means of identifying oncogenes. This presentation discusses a study in which the gene copy number of a putative oncogene (ZNF217) was assessed in 80 colon carcinomas by multiplex qu... Read More about Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR..

Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention. (2002)
Presentation / Conference Contribution
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2002. Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention. Presented at the 2002 British cancer research meeting (BCRM 2002), 30 June - 3 July 2002, Glasgow, UK.

Cytochrome P450 CYP1B1 is a member of a superfamily of haemoproteins that are central to the oxidative metabolism of a wide variety of endogenous and exogenous compounds. Several of these enzymes have an established role in the metabolic bio-transfor... Read More about Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention..

Morphological changes in MCF-7 human breast cancer cells in response to Bis-Naphthalimidopropylspermidine-treatment. (2002)
Journal Article
PAVLOV, V., RODILLA, V. and KONG THOO LIN, P. 2002. Morphological changes in MCF-7 human breast cancer cells in response to Bis-Naphthalimidopropylspermidine-treatment. Biotechnology and biotechnological equipment [online], 16(1), pages 118-123. Available from: https://doi.org/10.1080/13102818.2002.10819165

The effects of bis-naphthalimidopropylspermidine (BNIPSpd), a representative of a novel class of polyamine derivatives with antiproliferative properties on the morphology of MCF-7 human breast cancer cells were studied. BNIPSpd was shown to cause cyt... Read More about Morphological changes in MCF-7 human breast cancer cells in response to Bis-Naphthalimidopropylspermidine-treatment..

Goalsetting as a tool for involving people with learning disabilities in healthcare. (2002)
Thesis
YOUNG, A.F. 2002. Goalsetting as a tool for involving people with learning disabilities in healthcare. Robert Gordon University, PhD thesis.

Background: This research was undertaken during a period of rapid change within the NHS including the deinstitutionalisation of care, and increased emphasis on partnership working. The main aim of the study was to examine collaborative goalsetting as... Read More about Goalsetting as a tool for involving people with learning disabilities in healthcare..

Use of CYP1B1 inhibitors for treating cancer. (2001)
Patent
MURRAY, G.I., MELVIN, W.T. and MCFADYEN, M. 2001. Use of CYP1B1 inhibitors for treating cancer. International patent application PCT/GB2001/000548. International publication number WO/2001/058444 (WO 01/58444 A1), published 16.08.2001. Available from: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2001058444

CYP1B1 proteins and their role in metabolising or inactivating anti-cancer drugs are disclosed, together with compositions for treating cancer comprising a substance capable of inhibiting CYP1B1 protein and an anti-cancer drug (e.g. docetaxel, paclit... Read More about Use of CYP1B1 inhibitors for treating cancer..

Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. (2001)
Journal Article
MCFADYEN, M.C.E., CRUICKSHANK, M.E., MILLER, I.D., MCLEOD, H.L., MELVIN, W.T., HAITES, N.E., PARKIN, D. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. British journal of cancer [online], 85(2), pages 242-246. Available from: https://doi.org/10.1054/bjoc.2001.1907

Ovarian cancer is the most frequent cause of death from gynaecological malignancies world wide. Little improvement has been made in the long-term outcome of this disease, with the 5-year survival of patients only 30%. This poor prognosis is due to th... Read More about Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer..

Cytochrome P450 CYP1B1: a novel mechanism of drug resistance. (2001)
Presentation / Conference Contribution
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1: a novel mechanism of drug resistance. Presented at the 2001 British cancer research meeting (BCRM 2001), 1-4 July 2001, Leeds, UK.

CYP1B1 is a member of the cytochrome P450 enzymes, which are central to the oxidative metabolism of a wide range of substrates, including endogenous compounds involved in cell signaling, environmental carcinogens and anti-cancer drugs. This presentat... Read More about Cytochrome P450 CYP1B1: a novel mechanism of drug resistance..

Nursing perspectives on women, health and work in the socio-cultural context of poor communities in Northeast Thailand. (2001)
Thesis
JONGUDOMKARN, D. 2001. Nursing perspectives on women, health and work in the socio-cultural context of poor communities in Northeast Thailand. Robert Gordon University, PhD thesis.

Women from poor communities in Northeast Thailand can be considered as a disadvantaged group who have struggled against several problems in their daily living and who have worked hard to sustain their lives through unskilled labour. In such a strong... Read More about Nursing perspectives on women, health and work in the socio-cultural context of poor communities in Northeast Thailand..

Development, implementation and evaluation of harm reduction techniques for drug users. (2000)
Thesis
SCOTT, J. 2000. Development, implementation and evaluation of harm reduction techniques for drug users. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Recent strategies within health and social care state policies and interventions should be selected on the basis of evidence available to demonstrate their benefits. The provision of services for drug users is no exception to this. Harm reduction is... Read More about Development, implementation and evaluation of harm reduction techniques for drug users..

A prospective study of the incidence and nature of injuries to adult rugby players. (1990)
Journal Article
CLARK, D.R., ROUX, C. and NOAKES, T.D. 1990. A prospective study of the incidence and nature of injuries to adult rugby players. South African medical journal [online], 77(6), pages 559-562. Available from: http://tinyurl.com/ye295aea

The incidence and nature of injuries occurring in 8 adult club rugby teams was followed prospectively during the 1988 rugby season. The findings were compared with those from two similar studies in schoolboy rugby players. A total of 114 injuries wer... Read More about A prospective study of the incidence and nature of injuries to adult rugby players..