All Outputs (40)

The effect of administration of fenbendazole on the microbial hindgut population of the horse. (2018)
Journal Article
CROTCH-HARVEY, L., THOMAS, L.-A., WORGAN, H.J., DOUGLAS, J.-L., GILBY, D.E. and MCEWAN, N.R. 2018. The effect of administration of fenbendazole on the microbial hindgut population of the horse. Journal of equine science [online], 29(2), pages 47-51. Available from: https://doi.org/10.1294/jes.29.47

Anthelmintics are used as anti-worming agents. Although known to affect their target organisms, nothing has been published regarding their effect on other digestive tract organisms, or metabolites produced by them. The current work investigated effec... Read More about The effect of administration of fenbendazole on the microbial hindgut population of the horse..

Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages. (2018)
Journal Article
ALMPANIS, A., SWAIN, M., GATHERER, D. and MCEWAN, N. 2018. Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages. Microbial genomics [online], 4(4), article number 168. Available from: https://doi.org/10.1099/mgen.0.000168

Based on complete bacterial genome sequence data, we demonstrate a correlation between bacterial chromosome length and G+C content of the genome, with longer genomes having higher G+C contents. The correlation value decreases at shorter genome sizes... Read More about Correlation between bacterial G+C content, genome size and the G+C content of associated plasmids and bacteriophages..

Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014-2015. (2017)
Journal Article
ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2017. Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014-2015. Scientific data [online], 4, article No. 170161. Available from: https://doi.org/10.1038/sdata.2017.161

Nasopharyngeal swabs were taken from volunteers attending a general medical practice and a general hospital in Lancaster, UK, and at Lancaster University, in the winter of 2014-2015. 51 swabs were selected based on high RNA yield and allocated to dee... Read More about Nasopharyngeal metagenomic deep sequencing data, Lancaster, UK, 2014-2015..

Seasonal variations of the digestive tract of the Eurasian beaver castor fiber. (2017)
Journal Article
BELZECKI, G., MILTKO, R., KOWALIK, B., DEMIASZKIEWICZ, A.W., LACHOWICZ, J., GIZEJEWSKI, Z., OBIDZINSKI, A., and MCEWAN, N.R. 2018. Seasonal variations of the digestive tract of the Eurasian beaver castor fiber. Mammal research [online], 63(1), pages 21-31. Available from: https://doi.org/10.1007/s13364-017-0337-x

Forage availability for wild rodents varies with season. In turn, the composition of food can affect morphometric parameters of the digestive tract. This study was performed in Eurasian beavers (Castor fiber) whose population was close to extinction... Read More about Seasonal variations of the digestive tract of the Eurasian beaver castor fiber..

Evaluation of the microbiome of decaying alder nodules by next generation sequencing. (2017)
Journal Article
MCEWAN, N.R., WILKINSON T., GIRDWOOD, S.E., SNELLING, T.J., COLLINS, T., DOUGAL, K., JONES, D.L. and GODBOLD, D.L. 2017. Evaluation of the microbiome of decaying alder nodules by next generation sequencing. Endocytobiosis and cell research [online], 28(1), pages 14-19. Available from: http://zs.thulb.uni-jena.de/receive/jportal_jparticle_00501405

This work investigated the microbial content of decaying nodules from alders. The 16S rDNA composition of the microbiome of six senescent alder nodules was investigated by 454 sequencing. All nodules still had some Frankia sequences present, but in e... Read More about Evaluation of the microbiome of decaying alder nodules by next generation sequencing..

Genome sequence of human papillomavirus 23 strain HPV-23/Lancaster/2015. (2017)
Journal Article
ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2017. Genome sequence of human papillomavirus 23 strain HPV-23/Lancaster/2015. Genome announcements [online], 5(20), 00257-17. Available from: https://doi.org/10.1128/genomeA.00257-17

The genome of human papillomavirus type 23 (HPV-23; family Papillomaviridae, genus Betapapillomavirus, species Betapapillomavirus 2, type 23) was assembled by deep sequencing from nasopharyngeal swabs. The assembled genome is 2.7% divergent over its... Read More about Genome sequence of human papillomavirus 23 strain HPV-23/Lancaster/2015..

Influenza C in Lancaster, UK, in the winter of 2014-2015. (2017)
Journal Article
ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2017. Influenza C in Lancaster, UK, in the winter of 2014-2015. Scientific reports [online], 7, article number 46578. Available from: https://doi.org/10.1038/srep46578

Influenza C is not included in the annual seasonal influenza vaccine, and has historically been regarded as a minor respiratory pathogen. However, recent work has highlighted its potential role as a cause of pneumonia in infants. We performed nasopha... Read More about Influenza C in Lancaster, UK, in the winter of 2014-2015..

Factors affecting the development of laryngeal chondritis in sheep. (2017)
Journal Article
EDMUNDS, J.L., RODEN, J.A., FINCH., J.M. and MCEWAN, N.R. 2017. Factors affecting the development of laryngeal chondritis in sheep. Large animal review [online], 23(6), pages 219-222. Available from: https://cms.sivarnet.it/it/lar

Historic data (from 2005 to 2011) were collected and analysed from four flocks of pedigree Texel sheep in Ceredigion, West Wales and were used to investigate a range of factors associated with death due to laryngeal chondritis (n=82) relative to all... Read More about Factors affecting the development of laryngeal chondritis in sheep..

Genome sequence of human rhinovirus A22, strain Lancaster/2015. (2017)
Journal Article
ATKINSON, K.V., BISHOP, L.A., RHODES, G., SALEZ, N., MCEWAN, N.R., HEGARTY, M.J., ROBEY, J., HARDING, N., WETHERELL, S., LAUDER, R.M., PICKUP, R.W., WILKINSON, M. and GATHERER, D. 2017. Genome sequence of human rhinovirus A22, strain Lancaster/2015. Genome announcements [online], 5(12), article number 01713-16. Available from: https://doi.org/10.1128/genomeA.01713-16

The genome of human rhinovirus A22 (HRV-A22) was assembled by deep sequencing RNA samples from nasopharyngeal swabs. The assembled genome is 8.7% divergent from the HRV-A22 reference strain over its full length, and it is only the second full-length... Read More about Genome sequence of human rhinovirus A22, strain Lancaster/2015..

Interbreed variation in craniometrical parameters in sheep. (2017)
Journal Article
OWEN, M.H., DAVIES, R., BEARD, C.E., OLVERA RAMIREZ, A.M. and MCEWAN, N.R. 2017. Interbreed variation in craniometrical parameters in sheep. Large animal review [online], 23(5), pages 177-182. https://cms.sivarnet.it/it/lar

This work is the first investigation to compare craniometrical parameters between different breeds of sheep. Nine breeds or cross-breeds of sheep were studied, with all measurements being carried out on live animals at times of routine animal husband... Read More about Interbreed variation in craniometrical parameters in sheep..

Comparison of the microbial population in rabbits and guinea pigs by next generation sequencing. (2017)
Journal Article
CROWLEY, E.J., KING, J.M., WILKINSON, T., WORGAN, H.J., HUSON, K.M., ROSE, M.T. and MCEWAN, N.R. 2017. Comparison of the microbial population in rabbits and guinea pigs by next generation sequencing. PLOS one [online], 12(2), e0165779. Available from: https://doi.org/10.1371/journal.pone.0165779

This study aimed to determine the microbial composition of faeces from two groups of caecotrophagic animals; rabbits and guinea pigs. In addition the study aimed to determine the community present in the different organs in the rabbit. DNA was extrac... Read More about Comparison of the microbial population in rabbits and guinea pigs by next generation sequencing..

Effect of Entodinium caudatum on starch intake and glycogen formation by Eudiplodinium maggii in the rumen and reticulum. (2016)
Journal Article
BELZECKI, G., MCEWAN, N.R., KOWALIK, B., MICHALOWSKI, T. and MILTKO, R. 2017. Effect of Entodinium caudatum on starch intake and glycogen formation by Eudiplodinium maggii in the rumen and reticulum. European journal of protistology [online], 57, pages 38-49. Available from: https://doi.org/10.1016/j.ejop.2016.09.007

This study aimed to quantify the engulfed starch and reserve α-glucans (glycogen) in the cells of the ciliates Eudiplodinium maggii, as well the α-glucans in defaunated and selectively faunated sheep. The content of starch inside the cell of ciliates... Read More about Effect of Entodinium caudatum on starch intake and glycogen formation by Eudiplodinium maggii in the rumen and reticulum..

In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut. (2016)
Journal Article
EDMUNDS, J.L., WORGAN, H.J., DOUGAL, K., GIRDWOOD, S.E., DOUGLAS, J.-L. and MCEWAN, N.R. 2016. In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut. Journal of equine science [online], 27(2), pages 49-55. Available from: https://doi.org/10.1294/jes.27.49

The present study uses in vitro analytical techniques to investigate the effect of activated charcoal on the microbial community of the equine hindgut and the metabolites they produce. Incubations were performed in Wheaton bottles using a 50 ml incub... Read More about In vitro analysis of the effect of supplementation with activated charcoal on the equine hindgut..

Microbial diversity in the digestive tract of two different breeds of sheep. (2016)
Journal Article
DOUGLAS, J.-L., WORGAN, H.J., EASTON, G.L., PORET, L., WOLF, B.T., EDWARDS, A., DAVIES, E., ROSS, D. and MCEWAN, N.R. 2016. Microbial diversity in the digestive tract of two different breeds of sheep. Journal of applied microbiology [online], 120(5), pages 1382-1389. Available from: https://doi.org/10.1111/jam.13060

Aims: This work aims to determine the factors which play a role in establishing the microbial population throughout the digestive tract in ruminants and is necessary to enhance our understanding of microbial establishment and activity. Methods and Re... Read More about Microbial diversity in the digestive tract of two different breeds of sheep..

Isolation of macro-nuclear DNA from the rumen ciliate Entodinium caudatum. (2015)
Journal Article
YOUNG, K.W., THOMAS, N.A., DUVAL, S.M., NEWBOLD, J., FRIED, J., BROWN, D.S., HACKSTEIN, J.H.P., MICHALOWSKI, T. and MCEWAN, N.R. 2015. Isolation of macro-nuclear DNA from the rumen ciliate Entodinium caudatum. Endocytobiosis and cell research [online], 26, pages 50-55. Available from: https://zs.thulb.uni-jena.de/receive/jportal_jparticle_00355360

A method is described which allows isolation of macronuclear DNA from the rumen ciliate Entodinium caudatum. Ciliate cells were enriched from the total microbial population in the rumen of sheep with a single ciliate species present by sedimentation... Read More about Isolation of macro-nuclear DNA from the rumen ciliate Entodinium caudatum..

Lobes on Alnus glutinosa nodules contain a single major ribo-type of Frankia. (2015)
Journal Article
MCEWAN, N.R., SNELLING, T.J., COLLINS, T., GIRDWOOD, S.E., WILKINSON, T., DOUGAL, K., JONES, D.L. and GODBOLD, D.L. 2015. Lobes on Alnus glutinosa nodules contain a single major ribo-type of Frankia. Endocytobiosis and cell research [online], 26, pages 83-86. Available from: https://zs.thulb.uni-jena.de/receive/jportal_jparticle_00364367

This work investigated the microbial content of nodules from alders to determine how many ribotypes of Frankia were present and which, if any, other bacteria existed within nodes from the nodules. The bacterial content of alder nodules was investigat... Read More about Lobes on Alnus glutinosa nodules contain a single major ribo-type of Frankia..

The role of ciliate protozoa in the rumen. (2015)
Journal Article
NEWBOLD, C.J., DE LA FUENTE, G. BELANCHE, A. RAMOS-MORALES, E. and MCEWAN, N.R. 2015. The role of ciliate protozoa in the rumen. Frontiers in microbiology [online], 6, Article 1313. Available from: https://doi.org/10.3389/fmicb.2015.01313

First described in 1843, Rumen protozoa with their striking appearance were assumed to be important for the welfare of their host. However, despite contributing up to 50% of the bio-mass in the rumen, the role of protozoa in rumen microbial ecosystem... Read More about The role of ciliate protozoa in the rumen..

Comparative genetic diversity in a sample of pony breeds from the U.K. and North America: a case study in the conservation of global genetic resources. (2015)
Journal Article
WINTON, C.L., PLANTE, Y., HIND, P., MCMAHON, R., HEGARTY, M.J., MCEWAN, N.R., DAVIES-MOREL, M.C.G., MORGAN, C.M., POWELL, W. and NASH, D.M. 2015. Comparative genetic diversity in a sample of pony breeds from the U.K. and North America: a case study in the conservation of global genetic resources. Ecology and evolution [online], 5(16), pages 3507-3522. Available from: https://doi.org/10.1002/ece3.1562

Most species exist as subdivided ex situ daughter population(s) derived from a single original group of individuals. Such subdivision occurs for many reasons both natural and manmade. Traditional British and Irish pony breeds were introduced to North... Read More about Comparative genetic diversity in a sample of pony breeds from the U.K. and North America: a case study in the conservation of global genetic resources..

Sweat osmolarity shows intra-animal regional variation in the horse. (2015)
Journal Article
POTTS, S., THATCHER, R., JONES, A.W., WARREN, L.K., TENBROECK, S.H., NOTTAGE, F. and MCEWAN, N.R. 2015. Sweat osmolarity shows intra-animal regional variation in the horse. Veterinary dermatology [online], 26(5), pages 374-e85. Available from: https://doi.org/10.1111/vde.12225

Sweating is important in regulating body temperature, but can cause the loss of both fluids and electrolytes. In terms of studies on horses, the sweating process has been studied, but the variation in sweat osmolarity across the body has not. This wo... Read More about Sweat osmolarity shows intra-animal regional variation in the horse..

Assessment of genetic relationship between six populations of Welsh Mountain sheep using microsatellite markers. (2015)
Journal Article
HUSON, K.M., HARESIGN, W., HEGARTY, M.J., BLACKMORE, T.M., MORGAN, C. and MCEWAN, N.R. 2015. Assessment of genetic relationship between six populations of Welsh Mountain sheep using microsatellite markers. Czech journal of animal science [online], 60(5), pages 216-223. Available from: https://doi.org/10.17221/8171-CJAS

This study investigated the genetic relationship between 6 populations of Welsh Mountain sheep: 5 phenotypic breed-types within the Welsh Mountain (WM) sheep breed, which have each been bred in specific geographic areas of Wales, and the Black Welsh... Read More about Assessment of genetic relationship between six populations of Welsh Mountain sheep using microsatellite markers..