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All Projects (65)

Investigating the impact of adiposity-redox defence interaction on redox homeostasis and inflammatory and cancer-related pathways in human colonocytes Mar 15, 2021 - Mar 14, 2023
Colorectal cancer is the third most common cancer and the second most common cause of cancer-related death.
Increased body fat have been reported as one of the main factors responsible for the rise in colorectal cancer.
For this reaso... Read More about Investigating the impact of adiposity-redox defence interaction on redox homeostasis and inflammatory and cancer-related pathways in human colonocytes.

Dial a wavelength for exploiting the algal cell factory Oct 1, 2021 - Sep 30, 2025
This project aims to develop a new solution for cost effective production of microalgae, using efficient smart lighting that can adapt both intensity and wavelength during a growth cycle to target strains and specific products.

Nationwide surveillance of antimicrobial resistance in the Scottish population by wastewater-based epidemiology Oct 1, 2023 - Sep 30, 2027
Antimicrobial resistance (AMR) is one of the most significant threats to global health we face today. The WHO outlined in their AMR Global Action Plan that surveillance of AMR is essential to strengthen our knowledge and evidence base, and for the de... Read More about Nationwide surveillance of antimicrobial resistance in the Scottish population by wastewater-based epidemiology.

A novel in vitro model of the human intestinal epithelium in co-culture with “gut-like” dendritic cells Feb 1, 2023 - Dec 31, 2024
In the UK, over half a million people have an Inflammatory Bowel Disease, like Crohn’s disease or ulcerative colitis. These diseases cause painful symptoms like severe pain, diarrhoea, and weight loss. This is due to the body's immune system attackin... Read More about A novel in vitro model of the human intestinal epithelium in co-culture with “gut-like” dendritic cells.

Multitargets drug for Sepsis: Mechanistic studies of drug action through mitigating infection and inflammatory responses associated with sepsis. Oct 1, 2023 - Sep 30, 2025
Sepsis is a life-threatening clinical condition caused by an overreacting immune system fighting an infection. It is often treated with broad-spectrum antibiotics together with anti-inflammatory drugs. However, due to the heterogeneous nature of the... Read More about Multitargets drug for Sepsis: Mechanistic studies of drug action through mitigating infection and inflammatory responses associated with sepsis..

One Health Prescribing – New Analytical Methods to Inform Formulary Changes to Chiral Pharmaceuticals for Environmentally Friendlier Medicines Oct 1, 2023 - Sep 30, 2027
There is a need to reduce pollutants at source instead of relying on water treatment for their removal. The One Health Breakthrough Partnership is working to reduce pharmaceutical pollution entering the environment. This includes prescribing medicine... Read More about One Health Prescribing – New Analytical Methods to Inform Formulary Changes to Chiral Pharmaceuticals for Environmentally Friendlier Medicines.

Synthesis of substituted triazines and their investigation as corrosion inhibitors on mild steel and aluminium in corrosive environments Aug 1, 2023 - Dec 1, 2023
The serious consequences of the corrosion process have become a problem of worldwide significance - corrosion is the destructive attack of a material by reacting to its environment. Corrosion causes plant shutdowns, wastes valuable resources, causes... Read More about Synthesis of substituted triazines and their investigation as corrosion inhibitors on mild steel and aluminium in corrosive environments.

The role of Glutathione Peroxidase 4 (GPX4) and the GPX4 single-nucleotide polymorphism (SNP), rs713041, in metabolic syndrome associated vascular dysfunction Sep 1, 2023 - Feb 28, 2025
High blood sugar, high blood pressure, and obesity are all features of the ‘umbrella term’ metabolic syndrome (MetS) which affects 1 in 3 people over 50 years old in the UK. MetS increases the risk of developing heart disease and in particular the co... Read More about The role of Glutathione Peroxidase 4 (GPX4) and the GPX4 single-nucleotide polymorphism (SNP), rs713041, in metabolic syndrome associated vascular dysfunction.