All Outputs (1206)

The destruction of 2-methylisoborneol and geosmin using titanium dioxide photocatalysis. (2003)
Journal Article
LAWTON, L.A., ROBERTSON, P.K.J., ROBERTSON, R.F. and BRUCE, F.G. 2003. The destruction of 2-methylisoborneol and geosmin using titanium dioxide photocatalysis. Applied catalysis B: environmental [online], 44(1), pages 9-13. Available from: https://doi.org/10.1016/S0926-3373(03)00005-5

Geosmin (GSM) and 2-methylisoborneol (MIB) are semi-volatile compounds produced by cyanobacteria in surface waters. These compounds present problems to the drinking water industry and in aquaculture because they can taint water and fish producing an... Read More about The destruction of 2-methylisoborneol and geosmin using titanium dioxide photocatalysis..

Processes influencing surface interaction and photocatalytic destruction of microcystins on titanium dioxide photocatalysts. (2002)
Journal Article
LAWTON, L., ROBERTSON, P., CORNISH, B., MARR, I. and JASPARS, M. 2003. Processes influencing surface interaction and photocatalytic destruction of microcystins on titanium dioxide photocatalysts. Journal of catalysis [online], 213(1), pages 109-113. Available from: https://doi.org/10.1016/S0021-9517(02)00049-0

Microcystins are a family of hepatotoxic peptides produced by freshwater cyanobacteria. Their occurrence in drinking water is of concern since chronic exposure to these toxins causes tumor promotion. It is therefore essential to establish a reliable... Read More about Processes influencing surface interaction and photocatalytic destruction of microcystins on titanium dioxide photocatalysts..

Purification and characterisation of the lipid macroamphiphiles of propionibacterium acnes. (2002)
Thesis
WHALE, G.A. 2002. Purification and characterisation of the lipid macroamphiphiles of propionibacterium acnes. Robert Gordon University, PhD thesis. Hosted on OpenAIR [online]. Available from: https://doi.org/10.48526/rgu-wt-1905093

Lipid macroamphiphiles (LMAPs) are cell envelope components of bacteria that have been extensively associated with the pathogenesis of disease. It has been reported that these components can also influence the in vivo metabolism of lipids in mammals.... Read More about Purification and characterisation of the lipid macroamphiphiles of propionibacterium acnes..

Assessing pharmacist's intervention in supporting the management of Type 2 diabetes in a primary care setting. (2002)
Thesis
SOORAPAN, S. 2002. Assessing pharmacist's intervention in supporting the management of Type 2 diabetes in a primary care setting. Robert Gordon University, PhD thesis.

Type 2 diabetes mellitus is a chronic disease that is associated with substantial morbidity, mortality, and health care cost. All patients with diabetes require a high level of clinical care to prevent the development of diabetic complications. The a... Read More about Assessing pharmacist's intervention in supporting the management of Type 2 diabetes in a primary care setting..

Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. (2002)
Presentation / Conference
ROONEY, P.H., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR. Presented at the 184th Meeting of the Pathological Society of Great Britain and Ireland, 2-5 July 2002, Dublin, Ireland.

Detection of gene amplification is a process that is recognised as a means of identifying oncogenes. This presentation discusses a study in which the gene copy number of a putative oncogene (ZNF217) was assessed in 80 colon carcinomas by multiplex qu... Read More about Assessment of a putative oncogene ZNF217 in colorectal cancer by multiplex quantitative real-time PCR..

Morphological changes in MCF-7 human breast cancer cells in response to Bis-Naphthalimidopropylspermidine-treatment. (2002)
Journal Article
PAVLOV, V., RODILLA, V. and KONG THOO LIN, P. 2002. Morphological changes in MCF-7 human breast cancer cells in response to Bis-Naphthalimidopropylspermidine-treatment. Biotechnology and biotechnological equipment [online], 16(1), pages 118-123. Available from: https://doi.org/10.1080/13102818.2002.10819165

The effects of bis-naphthalimidopropylspermidine (BNIPSpd), a representative of a novel class of polyamine derivatives with antiproliferative properties on the morphology of MCF-7 human breast cancer cells were studied. BNIPSpd was shown to cause cyt... Read More about Morphological changes in MCF-7 human breast cancer cells in response to Bis-Naphthalimidopropylspermidine-treatment..

Quantitative analysis of the Ah receptor signalling pathway. (2002)
Presentation / Conference
MCFADYEN, M.C.E., ROONEY, P.H. and MURRAY, G.I. 2002. Quantitative analysis of the Ah receptor signalling pathway. Presented at the 2002 British cancer research meeting (BCRM 2002), 30 June - 3 July 2002, Glasgow, UK.

The aryl hydrocarbon receptor (AhR) is a ligand activated receptor. On dimerisation with the aryl hydrocarbon nuclear translocator (ARNT), AhR binds to xenobiotic responsive elements (XREs) that promote the activation of a battery of genes, including... Read More about Quantitative analysis of the Ah receptor signalling pathway..

Assessment of a putative oncogene ZNF217 within amplicon 20q by multiplex quantitative real-time PCR. (2002)
Presentation / Conference
ROONEY, P., BOONSONG, A., MCFADYEN, M., MCLEOD, H.L., CASSIDY, J. and MURRAY, G.I. 2002. Assessment of a putative oncogene ZNF217 within amplicon 20q by multiplex quantitative real-time PCR. Presented at the 2002 British cancer research meeting (BCRM 2002), 30 June - 3 July 2002, Glasgow, UK.

Detection of gene amplification is a recognised process through which oncogenes can be identified. In this study, we have coupled two powerful techniques - laser capture-microdissection and multiplex quantitative real-time PCR - to quickly and accura... Read More about Assessment of a putative oncogene ZNF217 within amplicon 20q by multiplex quantitative real-time PCR..

Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention. (2002)
Presentation / Conference
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2002. Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention. Presented at the 2002 British cancer research meeting (BCRM 2002), 30 June - 3 July 2002, Glasgow, UK.

Cytochrome P450 CYP1B1 is a member of a superfamily of haemoproteins that are central to the oxidative metabolism of a wide variety of endogenous and exogenous compounds. Several of these enzymes have an established role in the metabolic bio-transfor... Read More about Metabolically active cytochrome P450 CYP1B1 in solid tumours: a novel target for chemotherapeutic intervention..

Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR. (2002)
Journal Article
LIU, I., LAWTON, L.A., CORNISH, B. and ROBERTSON, P., 2002. Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR. Journal of photochemistry and photobiology A: chemistry [online], 148(1-3), pages 349-354. Available from: https://doi.org/10.1016/S1010-6030(02)00062-X

Cyanobacterial toxins present in drinking water sources pose a considerable threat to human health. Conventional water treatment systems have proven unreliable for the removal of these toxins and hence new techniques have been investigated. Previous... Read More about Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR..

Rerefinement of (μ-1,7,11,17-tetraoxa-2,6,12,16-tetraazacycloeicosane-κ4N1,N17:N7,N11)bis[dichlorozinc(II)]. [Dataset] (2002)
Dataset
KUKSA, V.A., WARDELL, S.M.S.V. , KONG THOO LIN, P. and HOWIE, R.A. 2002. Rerefinement of ([mu]-1,7,11,17-tetraoxa-2,6,12,16-tetra­aza­cyclo­ei­cosane-[kappa]4N1,N17:N7,N11)­bis­[di­chlorozinc(II)]. [Dataset]. Acta crystallographica section E: crystallographic communications [online], 58(2), pages m68-m69. Available from: https://doi.org/10.1107/S1600536802001654

This rerefinement of the title compound, [Zn2Cl4(C12H28­N4O4)], based on the original intensity data, differs from the original only in the exchange of the NH and O moieties of the oxa­aza-macrocycle, resulting in a dramatic improvement in the R fact... Read More about Rerefinement of (μ-1,7,11,17-tetraoxa-2,6,12,16-tetraazacycloeicosane-κ4N1,N17:N7,N11)bis[dichlorozinc(II)]. [Dataset].

Use of CYP1B1 inhibitors for treating cancer. (2001)
Patent
MURRAY, G.I., MELVIN, W.T. and MCFADYEN, M. 2001. Use of CYP1B1 inhibitors for treating cancer. International patent application PCT/GB2001/000548. International publication number WO/2001/058444 (WO 01/58444 A1), published 16.08.2001. Available from: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2001058444

CYP1B1 proteins and their role in metabolising or inactivating anti-cancer drugs are disclosed, together with compositions for treating cancer comprising a substance capable of inhibiting CYP1B1 protein and an anti-cancer drug (e.g. docetaxel, paclit... Read More about Use of CYP1B1 inhibitors for treating cancer..

Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. (2001)
Journal Article
MCFADYEN, M.C.E., CRUICKSHANK, M.E., MILLER, I.D., MCLEOD, H.L., MELVIN, W.T., HAITES, N.E., PARKIN, D. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. British journal of cancer [online], 85(2), pages 242-246. Available from: https://doi.org/10.1054/bjoc.2001.1907

Ovarian cancer is the most frequent cause of death from gynaecological malignancies world wide. Little improvement has been made in the long-term outcome of this disease, with the 5-year survival of patients only 30%. This poor prognosis is due to th... Read More about Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer..

Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. (2001)
Presentation / Conference
MCFADYEN, M.C.E., CRUICKSHANK, M.E., MILLER, I.D., MELVIN, W.T. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer. Presented at the 183rd Meeting of the Pathological Society of Great Britain and Ireland, 3-6 July 2001, Liverpool, UK.

Ovarian cancer is the leading cause of death from gynaecological malignances worldwide. This paper discusses a study in which the presence of CYP1B1 in primary and metastatic ovarian cancer was investigated through immunohistochemistry. The aim of th... Read More about Cytochrome P450 CYP1B1 over-expression in primary and metastatic ovarian cancer..

Cytochrome P450 CYP1B1: a novel mechanism of drug resistance. (2001)
Presentation / Conference
MCFADYEN, M.C.E., MELVIN, W.T. and MURRAY, G.I. 2001. Cytochrome P450 CYP1B1: a novel mechanism of drug resistance. Presented at the 2001 British cancer research meeting (BCRM 2001), 1-4 July 2001, Leeds, UK.

CYP1B1 is a member of the cytochrome P450 enzymes, which are central to the oxidative metabolism of a wide range of substrates, including endogenous compounds involved in cell signaling, environmental carcinogens and anti-cancer drugs. This presentat... Read More about Cytochrome P450 CYP1B1: a novel mechanism of drug resistance..

Digestive metabolism of glucosinolates: a novel approach using urinary markers for estimating the release of glucosinolate breakdown products in the gastro-intestinal tract of mammals. (2001)
Thesis
ROUZAUD, G.C.M. 2001. Digestive metabolism of glucosinolates: a novel approach using urinary markers for estimating the release of glucosinolate breakdown products in the gastro-intestinal tract of mammals. Robert Gordon University, PhD thesis.

Glucosinolates have been implicated as a mediator of the cancer-protective properties of cruciferous vegetables. Enzymatic hydrolysis of glucosinolates by plant or microbial myrosinase yields a range of metabolites including beneficial isothiocyanate... Read More about Digestive metabolism of glucosinolates: a novel approach using urinary markers for estimating the release of glucosinolate breakdown products in the gastro-intestinal tract of mammals..

The application of the Kelvin probe in materials science. (2000)
Thesis
LÄGEL, B. 2000. The application of the Kelvin probe in materials science. Robert Gordon University, PhD thesis.

This thesis reports on the application of the Kelvin probe in materials science and in particular on the study of metal and semiconductor surfaces in both ambient and UHV environments. The concept of the work function φ and its importance as a param... Read More about The application of the Kelvin probe in materials science..

Use of stable isotopes to assess phytoremediation of soils contaminated with cadmium and zinc. (2000)
Thesis
AYOUB, A.S. 2000. Use of stable isotopes to assess phytoremediation of soils contaminated with cadmium and zinc. Robert Gordon University, PhD thesis.

Land contaminated with heavy metals such as Cd and Zn can be remediated using a number of different approaches. Many of these strategies are very expensive (e. g. removal and disposal of the soil, covering the soil with uncontaminated soil, extractio... Read More about Use of stable isotopes to assess phytoremediation of soils contaminated with cadmium and zinc..

Development, implementation and evaluation of harm reduction techniques for drug users. (2000)
Thesis
SCOTT, J. 2000. Development, implementation and evaluation of harm reduction techniques for drug users. Robert Gordon University [online], PhD thesis. Available from: https://openair.rgu.ac.uk

Recent strategies within health and social care state policies and interventions should be selected on the basis of evidence available to demonstrate their benefits. The provision of services for drug users is no exception to this. Harm reduction is... Read More about Development, implementation and evaluation of harm reduction techniques for drug users..

The destruction of the cyanobacterial toxin microcystin-LR by semiconductor photocatalysis. (2000)
Thesis
CORNISH, B.J.P.A. 2000. The destruction of the cyanobacterial toxin microcystin-LR by semiconductor photocatalysis. Robert Gordon University, PhD thesis.

In fresh waters where cyanobacteria (blue-green algae) flourish, dense growths known as blooms occur. Such blooms present a threat to human and animal health as many of these cyanobacteria produce toxins. One such group of toxins are the microcystins... Read More about The destruction of the cyanobacterial toxin microcystin-LR by semiconductor photocatalysis..