Projects (39)

Development of Fast Field MRI as a novel method to monitor liver regeneration in non-alcoholic fatty liver disease (NAFLD) Mar 1, 2018 - Feb 28, 2019

Models of care in integrated joint boards Oct 1, 2017 - Sep 30, 2021
The project proposed seeks to explore the models of community nursing care within three integrated joint boards in NHS Grampian. With the introduction of Health and Social Care Integration, community services for patients and their families who have... Read More about Models of care in integrated joint boards.

sFRPs as a novel modulator of diastolic heart failure Oct 1, 2017 - Dec 31, 2021
Following a heart attack, or because of persistently high blood pressure the heart is damaged and has to work harder to circulate blood around the body. This condition is known as heart failure. In the UK alone, 500,000 people have heart failure re... Read More about sFRPs as a novel modulator of diastolic heart failure.

A human Glutathione Peroxidase 4 3 untranslated region knock-in mouse model to study susceptibility to colon cancer in obesity Apr 1, 2017 - Dec 31, 2021
Colorectal cancer (CRC) incidence is rising steadily and in parallel with increasing prevalence of obesity in Scotland. Recent data indicate that the highest incidence rates are in the North East. The increasing prevalence of obes... Read More about A human Glutathione Peroxidase 4 3 untranslated region knock-in mouse model to study susceptibility to colon cancer in obesity.

The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2 Jul 1, 2017 - Dec 31, 2019
Medicinal use of natural products, such as, extracts from plants have existed for many years particularly in China and are now widely available around the world. Several different types of cancer including breast cancer are becoming insensitive and r... Read More about The in vitro effect of natural products and anti-cancer agents: targeting the efflux transporter ABCG2.

Defining the emerging roles of GPR55 Oct 1, 2019 - Feb 4, 2023
The G-protein coupled receptor (GPCR) superfamily play crucial roles in cell communication. Given their involvement in neurological disorders, inflammatory and metabolic diseases, diabetes and cardiac dysfunction they represent the largest and most s... Read More about Defining the emerging roles of GPR55.

Extracting added value from the Seaweed Industry - a search for novel anti-obesity agents Oct 1, 2018 - Dec 31, 2022
Seaweed farming is a growing industry in the UK, with the majority of the biomass being used for the extraction of high yield products such as aliginates, or for use as biofuels.

However, a significant amount of the biomass remains un-used and t... Read More about Extracting added value from the Seaweed Industry - a search for novel anti-obesity agents.

Exploring the relationship between age-related zinc deficiency and obesity and the extent of myocardial damage following acute myocardial infarction Oct 1, 2018 - Jan 1, 2021
Zinc (Zn 2+) is a metal found in trace amounts in the body and plays an essential role in maintaining the healthy functioning of most organs, including the heart. The body does not store zinc in large quantities and so replenishment of Zn 2+ through... Read More about Exploring the relationship between age-related zinc deficiency and obesity and the extent of myocardial damage following acute myocardial infarction.

Protective effects of cannabidiol in doxorubicin induced cardiotoxicity Oct 1, 2018 - Dec 31, 2019

Acceptability of a wearable real-time neonatal device to enable home monitoring and treatment of jaundice for new born babies from a rural setting Oct 1, 2018 - Jul 31, 2024
Qualitative study exploring the acceptability of a neonatal jaundice home treatment and monitoring wearable device.

Protective effects of cannabidiol in combined chemotherapy induced cardiotoxicity Jul 8, 2019 - Sep 1, 2019
Doxorubicin, an anthracycline, is one of the most effective and commonly used drugs for the treatment of cancer. This anthracycline is used both alone and in combination with other chemotherapeutic agents such as taxanes e.g. paclitaxel. Despite its... Read More about Protective effects of cannabidiol in combined chemotherapy induced cardiotoxicity.

Investigating value as perceived and experienced by service users (2) Jan 1, 2019 - Dec 31, 2019
Community Pharmacy Scotland has commissioned Robert Gordon University and the University of Strathclyde to research the value of community pharmacy in Scotland as perceived and experienced by service users. The two universities will collaborate throu... Read More about Investigating value as perceived and experienced by service users (2).

'Microcystin Toolbox' - monitoring the impact of harmful algal blooms (HABs) in Indonesia by HPLC May 31, 2019 - May 31, 2020
Water is a precious resource subject to a host of extreme environmental pressures which can effect water quality and pose a hazard to human and animal health. Many water quality issues are due to hazardous microbes present in drinking water including... Read More about 'Microcystin Toolbox' - monitoring the impact of harmful algal blooms (HABs) in Indonesia by HPLC.

Exploration of family carers' experiences of support for rapid discharge arrangements for end of life care at home Jul 1, 2020 - Jun 30, 2023
Many patients and their families would prefer home-based end of life care, however, without appropriate support this can be a frightening experience. We aim to explore family carers experiences of support in preparation for rapid discharge for end of... Read More about Exploration of family carers' experiences of support for rapid discharge arrangements for end of life care at home.

Natural Products from Scottish Non-Food Crops as Multi-Drug Resistance Effectors in Cancer Cells Nov 1, 2020 - Jul 31, 2022
Cultivation of non-food crops for high value chemicals’ production for the pharmaceutical, nutraceutical, food and cosmeceutical industries is a growing area of industrial biotechnology. Plants have been used as a source of traditional medicines and... Read More about Natural Products from Scottish Non-Food Crops as Multi-Drug Resistance Effectors in Cancer Cells.

Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways. Sep 1, 2020 - Dec 31, 2022

The aim of this project is to synthesise a small discrete library of novel compounds based on our lead compound, by applying the methodology developed in our laboratory, and to study the mechanism of action of active one and confirm the multi targe... Read More about Multi-targets drug against Alzheimer (AD) disease: Mechanistic studies of drug action through amyloid and associated signalling pathways..

Building resilience in Health and Social Care students entering the workforce using digital networks to support their mental health and wellbeing during the Covid-19 pandemic May 1, 2020 - Nov 30, 2020
Due to the Covid-19 pandemic professional regulators are facilitating the inclusion of health and social care students in the workforce prior to satisfying previously essential criteria pre-registration and as new graduates. Around 1000 Robert Gordon... Read More about Building resilience in Health and Social Care students entering the workforce using digital networks to support their mental health and wellbeing during the Covid-19 pandemic.

A novel G protein-coupled receptor target for metabolic syndrome Sep 1, 2020 - Feb 28, 2022
Metabolic syndrome is the medical term for a group of risk factors that increase the likelihood of developing heart disease, diabetes, and stroke. The risk factors for metabolic syndrome include high blood pressure, high blood sugar (insulin resistan... Read More about A novel G protein-coupled receptor target for metabolic syndrome.

Primary care research priorities in Scotland after the coronavirus pandemic Jul 1, 2020 - Jun 30, 2021
The aim of this project is to reach a consensus for primary care research priorities in Scotland where uncertainties remain and set a research direction that will be relevant for patients, carers and generalist healthcare professionals in the afterma... Read More about Primary care research priorities in Scotland after the coronavirus pandemic.

Bioactivity of compounds derived from Amaryllicaea (Daffodil) Feb 1, 2021 - Jul 31, 2022
Heart Failure (HF) is a long-term complication of cardiovascular (high blood pressure and heart attack) and cardiovascular-related (obesity and metabolic syndrome) disorders and of drug-induced cardiotoxicity. HF is characterised by thickening (hype... Read More about Bioactivity of compounds derived from Amaryllicaea (Daffodil).